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251.

Induction of Heme Oxygenase-1 by Traditional Herb Mix Extract Improves MKN-74 Cell Survival and Reduces Stomach Bleeding in Rats by Ethanol and Aspirin in vivo

YoungJinKang, HyungSukMoon, HyeJungKim, HanGeukSeo, JaeHeunLee, KiChurlChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.2 4 65-70 (6 pages)

YoungJinKang, HyungSukMoon, HyeJungKim, HanGeukSeo, JaeHeunLee, KiChurlChang 저
...
- 3,000원
Chinese herb medicines have traditionally been used to treat or alleviate the symptom of various diseases. The rationale for use of certain herbs to certain disorder is now getting unveiled by modern technology. In the present study, we investigated whether herb mix extract (HMX), which is alleged to be useful for gastric ulcer, protects stomach from oxidative stress. Rats were allowed to normal diet with and without HMX (1, 5, 10 mg/kg) for 30 days. To induce gastric ulcer, ethanol (75%, 1.5...
252.

Glycyrrhizin and Morroniside Stimulate Mucin Secretion from Cultured Airway Epithelial Cells

HoJinHeo, HyunJaeLee, CheolsuKim, KunHoSon, YoungChoongKim, YoungSikKim, SamSikKang, YangChunPark, YunHeeKim, UnKyoSeo, JeongHoSeok, Choong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.6 4 317-322 (6 pages)

HoJinHeo, HyunJaeLee, CheolsuKim, KunHoSon, YoungChoongKim, YoungSikKim, SamSikKang, YangChunPark, YunHeeKim, UnKyoSeo, JeongHoSeok, Choong 저
...
- 3,000원
In this study, we investigated whether glycyrrhizin, prunetin and morroniside affect mucin secretion from cultured airway epithelial cells and compared the possible activities of these agents with the inhibitory action on mucin secretion by poly-L-lysine (PLL) and the stimulatory action by adenosine triphosphate (ATP). Confluent primary hamster tracheal surface epithelial (HTSE) cells were metabolically radiolabeled using 3H-glucosamine for 24 h and chased for 30 min in the presence of varying...
253.

Inhibition of Adenosine Triphosphate-stimulated Mucin Secretion from Airway Epithelial Cells by Schizandrin

HoJinHeo, HyunJaeLee, CheolsuKim, KiHwanBae, YoungSikKim, SamSikKang, YangChunPark, YunHeeKim, UnKyoSeo, JeongHoSeok, ChoongJaeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.5 5 251-254 (4 pages)

HoJinHeo, HyunJaeLee, CheolsuKim, KiHwanBae, YoungSikKim, SamSikKang, YangChunPark, YunHeeKim, UnKyoSeo, JeongHoSeok, ChoongJaeLee 저
...
- 1,500원
Schizandrae Fructus has been used for controlling respiratory allergic or inflammatory diseases in folk medicine and their components, schizandrin, schizandrin-A and gomisin-A were reported to have diverse biological effects. In this study, we investigated whether schizandrin, schizandrin-A and gomisin-A affect adenosine triphosphate (ATP)-induced mucin secretion from cultured airway epithelial cells. Confluent primary hamster tracheal surface epithelial (HTSE) cells were metabolically...
254.

Gene Expression Profile in Microglia following Ischemia- Reperfusion Injury

JuHyeonOh, HyungSooHan, JaeSikPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.4 2 173-180 (8 pages)

JuHyeonOh, HyungSooHan, JaeSikPark 저
...
- 3,000원
Microglial activation is thought to play a role in the pathogenesis of many brain disorders. Therefore, understanding the response of microglia to noxious stimuli may provide insights into their role in disorders such as stroke and neurodegeneration. Many genes involved in this response have been identified individually, but not systematically. In this regards, the microarray system permitted to screen a large number of genes in biological or pathological processes. Therefore, we used microarray...
255.

p66shc Adaptor Protein Suppresses the Activation of Endothelial Nitric Oxide Synthase in Mouse Embryonic Fibroblasts

SangKiLee, YoungShinKim, CukSeongKim, SookJinSon, DaeGoonYoo, KwonHoLee, SangDoLee, JinBongPark, ByeongHwaJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.3 7 155-160 (6 pages)

SangKiLee, YoungShinKim, CukSeongKim, SookJinSon, DaeGoonYoo, KwonHoLee, SangDoLee, JinBongPark, ByeongHwaJeon 저
...
- 3,000원
Among the Shc proteins, p66shc is known to be related to oxidative stress responses and regulation of the production of reactive oxygen species (ROS). The present study was undertaken to investigate the role of p66shc on endothelial nitric oxide synthase (eNOS) activity in the mouse embryonic fibroblasts (MEFs). When wild type (WT) or p66shc (⁣/⁣) MEFs were transfected with full length of eNOS cDNA, the expression and activity of eNOS protein were higher in the p66shc...
256.

Effects of Pharmacological Modulators of Ca2+-activated K+ Channels on Proliferation of Human Dermal Fibroblast

JihyunYun, TaehoKim, SoonchulMyung, HyoweonBang, InjaLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.2 6 95-100 (6 pages)

JihyunYun, TaehoKim, SoonchulMyung, HyoweonBang, InjaLim 저
...
- 3,000원
Employing electrophysiological and cell proliferation assay techniques, we studied the effects of Ca2⁢- activated K⁢ channel modulators on the proliferation of human dermal fibroblasts, which is important in wound healing. Macroscopic voltage-dependent outward K⁢ currents were found at about ⁣40 mV stepped from a holding potential of ⁣70 mV. The amplitude of K⁢ current was increased by NS1619, a specific large-conductance Ca2⁢-activated K⁢ (BK)...
257.

Effects of Ambroxol, S-carboxymethylcysteine, Dextromethorphan and Noscapine on Mucin Release from Airway Goblet Cells

HoJinHeo, HyunJaeLee, ChiSoonYoon, SeungPyongLim, JeongHoSeok, UnKyoSeo, ChoongJaeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.6 2 323-326 (4 pages)

HoJinHeo, HyunJaeLee, ChiSoonYoon, SeungPyongLim, JeongHoSeok, UnKyoSeo, ChoongJaeLee 저
...
- 1,500원
In the present study, we investigated whether ambroxol, S-carboxymethyl-L-cysteine, dextromethorphan and noscapine affect mucin release from airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled and chased for 30 min in the presence of varying concentrations of the above agents to assess the effects on 3H-mucin release. Noscapine stimulated mucin release during 30 min of treatment period in a dose-dependent manner. However, ambroxol,...
258.

Differential Activation of Ras/Raf/MAPK Pathway between Heart and Cerebral Artery in Isoproterenol-induced Cardiac Hypertrophy

HyunjuKim, NariKim, HyunJoo, JaeBoumYoum, WonSunPark, MohamedWarda, SunghyunKang, VuThiThu, TranMinhKhoa, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.5 7 299-304 (6 pages)

HyunjuKim, NariKim, HyunJoo, JaeBoumYoum, WonSunPark, MohamedWarda, SunghyunKang, VuThiThu, TranMinhKhoa, JinHan 저
...
- 3,000원
Cardiac hypertrophy contributes an increased risk to major cerebrovascular events. However, the molecular mechanisms underlying cerebrovascular dysfunction during cardiac hypertrophy have not yet been characterized. In the present study, we examined the molecular mechanism of isoproterenol (ISO)-evoked activation of Ras/Raf/MAPK pathways as well as PKA activity in cerebral artery of rabbits, and we also studied whether the activations of these signaling pathways were altered in cerebral artery,...
259.

Effects ofSphingosine-1-phosphate, Furosemide and Indomethacin on Mucin Release from Airway Goblet Cells

Ju-OckKim, HyungSooKim, Sun-YoungKim, Seong-SooJeong, HoJinHeo, JeongHoSeok, ChoongJaeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 4 155-158 (4 pages)

Ju-OckKim, HyungSooKim, Sun-YoungKim, Seong-SooJeong, HoJinHeo, JeongHoSeok, ChoongJaeLee 저
...
- 1,500원
In this study, we investigated whether sphingosine-1-phosphate, furosemide, and indomethacin affect mucin release from airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled and chased for 30 min or 24 hr in the presence of varying concentrations of the above agents to assess the effects on 3H-mucin release. Sphingosine-1-phosphate stimulated mucin release during 30 min of treatment period in a dose-dependent manner. However, furosemide...
260.

Effects of PCB Congeners in Rodent Neuronal Cells in Culture

Sun-YoungKimJae-HoYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 2 9-16 (8 pages)

Sun-YoungKimJae-HoYang 저
...
- 3,000원
We attempted to analyze the mechanism of polychlorinated biphenyl (PCB)-induced neurotoxicity and identify the target molecules in the neuronal cells for PCBs.Since the developing neuron is particularly sensitive to PCB-induced neurotoxicity, we isolated cerebellar granule cells derived from 7-day old Sprague Dawley (SD) rats and grew cells in culture for additional 7 days to mimic PND-14 conditions. Only non-coplanar PCBs at a high dose showed a significant increase of total protein kinase C...

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