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261.

Cardamonin inhibits agonist-induced vascular contractility via Rho-kinase and MEK inhibition

HyunDongJe, JiHoonJeong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 9 69-74 (6 pages)

HyunDongJe, JiHoonJeong 저
...
- 3,000원
The present study was undertaken to investigate the influence of cardamonin on vascular smooth muscle contractility and to determine the mechanism(s) involved. Denuded aortic rings from male rats were used and isometric contractions were recorded and combined with molecular experiments. Cardamonin significantly relaxed fluoride-, phenylephrine-, and phorbol ester-induced vascular contractions, suggesting that it has an anti-hypertensive effect on agonist-induced vascular contraction regardless...
262.

Effects of CoCl2 on multi-lineage differentiation of C3H/10T1/2 mesenchymal stem cells

HongIlYoo, YeonHeeMoon, MinSeokKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 7 53-62 (10 pages)

HongIlYoo, YeonHeeMoon, MinSeokKim 저
...
- 3,000원
Mesenchymal stem cells (MSCs) in the bone marrow and other somatic tissues reside in an environment with relative low oxygen tension. Cobalt chloride (CoCl2) can mimic hypoxic conditions through transcriptional changes of some genes including hypoxia-inducible factor-1a (HIF-1a) and vascular endothelial growth factor (VEGF). This study evaluated the potential role of CoCl2 preconditioning on multi-lineage differentiation of C3H/10T1/2, a murine MSC line to understand its possible molecular...
263.

Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis

Ju-HyungPark, GeunMookPark, Jin-KyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 5 335-340 (6 pages)

Ju-HyungPark, GeunMookPark, Jin-KyungKim 저
...
- 3,000원
Here, we investigated the role of zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, on angiogenesis using human umbilical vein endothelial cells (HUVECs). Zerumbone inhibited HUVECs proliferation, migration and tubule formation, as well as angiogenic activity by rat aorta explants. In particular, zerumbone inhibited phosphorylation of vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1, which are key regulators of endothelial cell function...
264.

Effects of Local Pancreatic Renin-Angiotensin System on the Microcirculation of Rat with Severe Acute Pancreatitis

ZhijianPan, LingFeng, HaochengLong, HuiWang, JiaruiFeng, FeixiangChen 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 1 299-307 (9 pages)

ZhijianPan, LingFeng, HaochengLong, HuiWang, JiaruiFeng, FeixiangChen 저
...
- 3,000원
Severe acute pancreatitis (SAP) is normally related to multiorgan dysfunction and local complications. Studies have found that local pancreatic renin-angiotensin system (RAS) was significantly upregulated in drug-induced SAP. The present study aimed to investigate the effects of angiotensin II receptors inhibitor valsartan on dual role of RAS in SAP in a rat model and to elucidate the underlying mechanisms. 3.8% sodium taurocholate (1 ml/kg) was injected to the pancreatic capsule in order for...
265.

Effect of Glutamate on the Vestibulo-Solitary Projection after Sodium Nitroprusside-Induced Hypotension in Conscious Rats

Li-WeiLi, Guang-ShiJin, Yan-ZhaoYang, AbdulNasirAmeer, MinSunKim, ByungRimPark, Yuan-ZheJin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 13 275-281 (7 pages)

Li-WeiLi, Guang-ShiJin, Yan-ZhaoYang, AbdulNasirAmeer, MinSunKim, ByungRimPark, Yuan-ZheJin 저
...
- 3,000원
by pretreatment with glutamate receptor antagonists (MK801 or CNQX) in the MVN. Microinjection of glutamate receptor agonists (NMDA or AMPA) into the MVN increased the expression of both pERK and c-Fos protein in the NTS without causing changes in blood pressure. These results indicate that both NMDA and AMPA receptors play a significant role in the vestibulo-solitary projection of the VSR pathway for maintaining blood pressure, and that glutamatergic transmission in this projection might play a...
266.

Analysis of the Baroreceptor and Vestibular Receptor Inputs in the Rostral Ventrolateral Medulla following Hypotension in Conscious Rats

YanLan, Huan-JunLu, XianJiang, Li-WeiLi, Yan-ZhaoYang, Guang-ShiJin, JooYoungPark, MinSunKim, ByungRimPark, Yuan-ZheJin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 11 159-165 (7 pages)

YanLan, Huan-JunLu, XianJiang, Li-WeiLi, Yan-ZhaoYang, Guang-ShiJin, JooYoungPark, MinSunKim, ByungRimPark, Yuan-ZheJin 저
...
- 3,000원
to maintain blood pressure during postural movement. The contribution of baroreceptors and vestibular receptors in the maintenance of blood pressure following hypotension were quantitatively analyzed by measuring phosphorylated extracellular regulated protein kinase (pERK) expression and glutamate release in the RVLM. The expression of pERK and glutamate release in the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or sinoaortic denervation (SAD)...
267.

Anti-inflammatory, Antioxidant and Antimicrobial Effects of Artemisinin Extracts from Artemisia annua L.

Wan-SuKim, WooJinChoi, SunwooLee, WooJoongKim, DongChaeLee, , UyDongSohn, Hyoung-ShikShin, WonyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 4 21-28 (8 pages)

Wan-SuKim, WooJinChoi, SunwooLee, WooJoongKim, DongChaeLee, , UyDongSohn, Hyoung-ShikShin, WonyongKim 저
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- 3,000원
The anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of Artemisia annua L. were evaluated. All 4 artemisinin- containing extracts had anti-inflammatory effects. Of these, the acetone extract had the greatest inhibitory effect on lipopolysaccharide-induced nitric oxide (NO), prostaglandin E2 (PGE2), and pro- inflammatory cytokine (IL-1β, IL-6, and IL-10) production. Antioxidant activity evaluations revealed...
268.

Berberine Prevents Intestinal Mucosal Barrier Damage During Early Phase of Sepsis in Rat through the Toll-Like Receptors Signaling Pathway

Guo-xunLi, Xi-moWang, TaoJiang, Jian-fengGong, Ling-yingNiu, NingLi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 1 1-8 (8 pages)

Guo-xunLi, Xi-moWang, TaoJiang, Jian-fengGong, Ling-yingNiu, NingLi 저
...
- 3,000원
Our previous study has shown berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway. In this study, we explored the regulatory effects of berberine on Toll-like receptors during the intestinal mucosal damaging process in rats. Male Sprague-Dawlay (SD) rats were treated with berberine for 5 d before undergoing cecal ligation and puncture (CLP) to induce polymicrobial sepsis. The...
269.

Inhibitory Effects of Ginsenoside-Rb2 on Nicotinic Stimulation-Evoked Catecholamine Secretion

Hyo-JeongLim, Hyun-YoungLee, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 12 431-439 (9 pages)

Hyo-JeongLim, Hyun-YoungLee, Dong-YoonLim 저
...
- 3,000원
The aim of the present study was to investigate whether ginsenoside-Rb2 (Rb2) can affect the secretion of catecholamines (CA) in the perfused model of the rat adrenal medulla. Rb2 (3∼30 μM), perfused into an adrenal vein for 90 min, inhibited ACh (5.32 mM)-evoked CA secretory response in a dose- and time-dependent fashion. Rb2 (10 μM) also time-dependently inhibited the CA secretion evoked by DMPP (100 μM, a selective neuronal nicotinic receptor agonist) and high K+ (56 mM, a direct membrane...
270.

Aortic Remodelling in Chronic Nicotine-Administered Rat

SatirahZainalabidin, SitiBalkisBudin, AnRamalingam, YiChengLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 9 411-418 (8 pages)

SatirahZainalabidin, SitiBalkisBudin, AnRamalingam, YiChengLim 저
...
- 3,000원
Vascular remodelling is an adaptive mechanism, which counteracts pressure changes in blood circulation. Nicotine content in cigarette increases the risk of hypertension. The exact relationship between nicotine and vascular remodelling still remain unknown. Current study was aimed to determine the effect of clinically relevant dosage of nicotine (equivalent to light smoker) on aortic reactivity, oxidative stress markers and histomorphological changes. Twelve age-matched male Sprague-Dawley rats...

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