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Effect of Stimulus Waveform of Biphasic Current Pulse on Retinal Ganglion Cell Responses in Retinal Degeneration (rd1) mice
KunNoAhn, JeongYeolAhn, Jae-hyungKim, KyoungrokCho, Kyo-inKoo, SolomonS.Senok, YongSookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 12 167-175 (9 pages)
A retinal prosthesis is being developed for the restoration of vision in patients with retinitis pigmentosa (RP) and age-related macular degeneration (AMD). Determining optimal electrical stimulation parameters for the prosthesis is one of the most important elements for the development of a viable retinal prosthesis. Here, we investigated the effects of different charge-balanced biphasic pulses with regard to their effectiveness in evoking retinal ganglion cell (RGC) responses. Retinal... -
The Effects of Eupatilin (Stillen�) on Motility of Human Lower Gastrointestinal Tracts
Seung-BumRyoo, Heung-KwonOh, SungAYu, , SangHuiMoon, EunKyungChoe, , TaeYoungOh, KyuJooPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 5 383-390 (8 pages)
of eupatilin. The amplitude, AUC, and frequency of tension recordings from circular and longitudinal smooth muscle strips and bowel segments of the ileum and colon were significantly decreased after admission of eupatilin. Eupatilin elicited dose-dependent decreases during segmental tension recordings. In conclusion, eupatilin (StillenⓇ) showed inhibitory effects on the human ileum and colon. We propose that this drug may be useful for treating diseases that increase bowel motility, but... -
The Downregulation of Somatic A-Type K+ Channels Requires the Activation of Synaptic NMDA Receptors in Young Hippocampal Neurons of Rats
Moon-SeokKang, Yoon-SilYang, Seon-HeeKim, Joo-MinPark, Su-YongEun, Sung-CherlJung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 7 135-141 (7 pages)
The downregulation of A-type K+ channels (IA channels) accompanying enhanced somatic excitability can mediate epileptogenic conditions in mammalian central nervous system. As IA channels are domi-nantly targeted by dendritic and postsynaptic processings during synaptic plasticity, it is presumable that they may act as cellular linkers between synaptic responses and somatic processings under various excitable conditions. In the present study, we electrophysiologically tested if the downregulation... -
Effects of Serotonin on the Induction of Long-term Depression in the Rat Visual Cortex
Hyun-JongJang, Kwang-HyunCho, , Sung-WonPark, Myung-JunKim, ShinHeeYoon, Duck-JooRhie 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 14 337-343 (7 pages)
Long-term potentiation (LTP) and long-term depression (LTD) have both been studied as mechanisms of ocular dominance plasticity in the rat visual cortex. In a previous study, we suggested that a developmental increase in serotonin [5-hydroxytryptamine (5-HT)] might be involved in the decline of LTP, since 5-HT inhibited its induction. In the present study, to further understand the role of 5-HT in a developmental decrease in plasticity, we investigated the effect of 5-HT on the induction of LTD... -
Magnesium Suppresses the Responses of Dorsal Horn Cell to Noxious Stimuli in the Rat
HongKeeShin, JinHyukKim, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 1 237-244 (8 pages)
Magnesium ion is known to selectively block the N-methyl-D-aspartate (NMDA)-induced responses and to have anticonvulsive action, neuroprotective effect and antinociceptive action in the behavioral test. In this study, we investigated the effect of Mg2 on the responses of dorsal horn neurons to cutaneous thermal stimulation and graded electrical stimulation of afferent nerves as well as to excitatory amino acids and also elucidated whether the actions of Ca2 and Mg2 are... -
Blockade of Intrinsic Oscillatory Activity of Cerebellar Purkinje Cells by Apamin and Nickel
WhasookSeo, JeanC.Strahlendorf, HowardK.Strahlendorf 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 2 477-484 (8 pages)
Intracellular recordings of oscillatory firing (bursting activity) were obtained from Purkinje cells (PCs) in rat cerebellar slices. Apamin inhibited post-burst hyperpolarizations (PBHs) progressively and finally terminated oscillatory firing activity of PCs. Apamin did not affect the amplitude or duration of the after-hyperpolarization (AHP) between spikes within the burst. In the voltage clamp mode, apamin shifted the whole-cell, quasi-steady state I/V relationship in an inward direction and... -
Neuroendocrine Control of Gonadotropin Secretion during the Menstrual Cycle
Ryu Kyung-Za 대한약리학회 대한약리학잡지 20 Pages
대한약리학회 대한약리학잡지 1987, 제 23권 제 2호 1 57-76 (20 pages)
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Synapse VS. Function: A Central Theme in Physiology
Ito, Masao 대한생리학회 대한생리학회지 18 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 1호 1 1-18 (18 pages)
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An Integrated Modeling Approach for Predicting Potential Epidemics of Bacterial Blossom Blight in Kiwifruit under Climate Change
Kwang-Hyung Kim, Young Jin Koh 한국식물병리학회 The Plant Pathology Journal 14 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 5호 7 459-472 (14 pages)
The increasing variation in climatic conditions under climate change directly influences plant-microbe interactions. To account for as many variables as possible that may play critical roles in such interactions, the use of an integrated modeling approach is necessary. Here, we report for the first time a local impact assessment and adaptation study of future epidemics of kiwifruit bacterial blossom blight (KBB) in Jeonnam province, Korea, using an integrated modeling approach. This study... -
웹 서비스에 환경에서 빅데이터 기반 이상행위 탐지 기술
신동진(Dongjin Shin), 이호근(Hogeun Lee), 은종민(Jongmin Eun), 김정준(Jeongjoon Kim), 박정민(JeongMin Park) 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 20 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2018, 제 8권 제 4호 21 231-250 (20 pages)
본 논문은 웹 서비스의 로그와 게시판 데이터베이스 정보를 수집하고 이상행위에 대한 분석을 위한 빅데이터 기반의 웹 서비스 로그와 게시판 분석 연구에 관해 소개한다. 기존의 웹 서비스의 필터링 방식은 관리자가 직접 수 많은 데이터들을 모니터링 후 특정 키워드를 등록하고, 악성 사용자를 직접 등록해서 필터링하는 방식으로 진행되었다. 하지만 이 방식은 사람이 직접 키워드 업데이트를 해주어야 하고, 스팸 키워드에 일치해야만 필터링이 되어 조금만 다른 키워드로 글을 등록하면 필터링이 되지 않았다. 따라서 본 논문에서는...


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