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쥐 척수후각세포의 유해자극 반응에 대한 칼슘이온통로 차단제의 억제작용 Calcium Channel Blockers Suppress the Responses of Rat Dorsal Horn Cell to Nociceptive Input
신홍기, 강석한, 김기순, HongKeeShin, SokHanKang, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 3 625-637 (13 pages)
Calcium ions are implicated in a variety of physiological functions, including enzyme activity, membrane excitability, neurotransmitter release, and synaptic transmission, etc. Calcium antagonists have been known to be effective for the treatment of exertional angina and essential hypertension. Selective and nonselective voltage-dependent calcium channel blockers also have inhibitory action on the acute and tonic pain behaviors resulting from thermal stimulation, subcutaneous formalin injection... -
Effect of UV Irradiation and Rebamipide on the Blood Flow and Viability of Rabbit Skin Flap
Eung-JooSuh, Hyoung-ChulChoi, Uy-DongSohn, Jeoung-HeeHa, Kwang-YounLee, Won-JoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 14 581-589 (9 pages)
This study was undertaken to examine the effects of ultraviolet light (UVL) and rebamipide on the cutaneous blood flow and tissue survival on rabbit skin flap. In a random bipedicle flap, Laser Doppler Flowmetry (LDF) was employed to measure the blood flow of flap (BFF). Wound Margin Strength (WMS) measured by force transducer and Light microscophy were used for evaluation of tissue viability. Single exposure to UVL increased the BFF gradually for more than 15 hours, and decreased the... -
Blockade of Intrinsic Oscillatory Activity of Cerebellar Purkinje Cells by Apamin and Nickel
WhasookSeo, JeanC.Strahlendorf, HowardK.Strahlendorf 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 2 477-484 (8 pages)
Intracellular recordings of oscillatory firing (bursting activity) were obtained from Purkinje cells (PCs) in rat cerebellar slices. Apamin inhibited post-burst hyperpolarizations (PBHs) progressively and finally terminated oscillatory firing activity of PCs. Apamin did not affect the amplitude or duration of the after-hyperpolarization (AHP) between spikes within the burst. In the voltage clamp mode, apamin shifted the whole-cell, quasi-steady state I/V relationship in an inward direction and... -
신경세포가 별아교세포의 아교섬유성 산단백질 표현에 미치는 영향 Effect of Glial-neuronal Cell Co-culture on GFAP Expression of Astrocytes
배형미, 박정선, 연동수, HyungmiBae, JungsunPark, DongsooYeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 7 285-296 (12 pages)
brain transforms resting astrocytes to their reactive form, the hallmark of which is an increase in glial fibrillary acidic protein (GFAP), the major intermediate filament protein of their cell type. The overall glial response after brain injury is referred to as reactive gliosis. Glial-neuronal interaction is important for neuronal migration, neurite outgrowth and axonal guidance during ontogenic development. Although much attention has been given to glial regulation of neuronal development and... -
일측 전정기관 손상 흰쥐에서 동측의 내측 전정신경핵 활동성에 대한 전정기관의 전기자극 효과
이문영, 김민선, 박병림 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 5 263-273 (11 pages)
Effects of Electrical Stimulation of the Vestibular System on Neuronal Activity of the Ipsilateral Medial Vestibular Nuclei Following Unilateral Labyrinthectomy in Rats. Moon Yong Lee, Min Sun Kim, and Byung Rim Park Department of Physiology, Wonkwang University School of Medicine, Medicinal Resources Research Center of W onkwang University, Iksan 570 - 749, Korea The purpose of this stu야 was to evaluate t뾰 effects of electrical stimulation on vestibular compensation following ULX in... -
신경병증성 통증 모델 쥐에서 뇌간 핵의 전기자극이 후각세포의 기계자극에 대한 반응도에 미치는 영향 Effects of Electrical Stimulation of Brainstem Nuclei on Dorsal Horn Neuron Responses to Mechanical Stimuli in a Rat Model of Neuropathic Pain
임중우, 최윤, 곽영섭, 남택상, 백광세, JoongWooLeem, YoonChoi, YoungSeobGwak, TaikSangNam, KwangSePaik 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 3 241-249 (9 pages)
The aim of the present study is to examine the brainstem sites where the electrical stimulation produces a suppression of dorsal horn neuron responses of neuropathic rats. An experimental neuropathy was induced by a unilateral ligation of L5-L6 spinal nerves of rats. Ten to 15 days after surgery, the spinal cord was exposed and single-unit recording was made on wide dynamic range (WDR) neurons in the dorsal horn. Neuronal responses to mechanical stimuli applied to somatic receptive fields were... -
Cloning of Mouse AQP-CD Gene
JinSupJung, JooInKim, SaeOkOh, MiYoungPark, HaeRhanBae, SangHoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 9 195-200 (6 pages)
Water transport in highly-permeable membranes is facilitated by some specialized pathways, which are called aquaporins (AQP). AQP1 (AQP-CHIP) is the first recognized aquaporin identified from red cells and renal proximal tubules. Up until now 4 other aquaporin homologs have been reported. Each aquaporin has its unique tissue distribution and regulatory mechanims. To elucidate molecular mechanisms for their transcription regulation and tissue-specific expression isolation of aquaporin genes is... -
Two Types of Voltage-dependent Outward Potassium Currents in Smooth Muscle Cells of Rabbit Basilar Atery
TongMookKang, InsukSo, DaeYongUhm, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 15 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 7 169-183 (15 pages)
We have investigated the two types of voltage-dependent outward potassium (K) currents, i.e. delayed rectifier K current (IK(V)) and 'A-like' transient outward K current (Ito) with patch-clamp technique in single smooth muscle cells (SMCs) isolated from rabbit basilar artery, and investigated the characteristics of them. The time-courses of activation were well fitted by exponential function raised to second power (n2) in IK(v) and fourth power (n4) in Ito. The activation, inactivation and... -
The Influence of N6-cyclopentyladenosine and Magnesium on Norepinephrine Release in the Rat Hippocampus
YeungBongPark, SangDukPark, BongKyuChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 3 135-142 (8 pages)
As it has been reported that the depolarization-induced norepinephrine (NE) release is modulated by activation of presynaptic A1-adenosine heteroreceptor and various lines of evidence indicate that A2-adenosine receptor also presents in hippocampus, and that the adenosine effect is magnesium dependent, the present study was undertaken to delineate the role of adenosine receptors in the modulation of hippocampal NE release. Slices from the rat hippocampus were equilibrated with [3H]-NE and the... -
Pharmacological Evidence that Cromakalim Inhibits Ca2+ Release from Intracellular Stores in Porcine Coronary Artery
ByungYongRhim, SunHwaHong, ChiDaeKim, WonSukLee, KiWhanHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 4 27-34 (8 pages)
In the present study, it was aimed to further indentify the intracellular action mechansm of cromakalim and levcromakalim in the porcine coronary artery. In intact porcine coronary arterial strips loaded with fura-2/AM, acetylcholine caused an increase in intracellular free Ca2 ([Ca2]i) in association with a contraction in a concentration-dependent manner. Cromakalim (1 ㄍM) caused a reduction in acetylcholine-induced increased [Ca2]i not only in the mormal...


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