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281.

Phenotype of peroxisome proliferator-activated receptor-α(PPARα)deficient mice on mixed background fed high fat diet

Bang Hyun Kim, Young Suk Won, Eun-Young Kim, Mijung Yoon, Ki-Taek Nam, Goo Taeg Oh, Dae-Yong Kim 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2003, 제 4권 제 3호 7 239-244 (6 pages)

Bang Hyun Kim, Young Suk Won, Eun-Young Kim, Mijung Yoon, Ki-Taek Nam, Goo Taeg Oh, Dae-Yong Kim 저
...
- 3,000원
Considerable controversy exists in determining the role of peroxisome proliferator-activated receptor-α (PPARα) on obesity. Previous reports demonstrated that PPARα is a critical modulator of lipid homeostasis, but the overt, obese phenotypic characterization in the strain of PPAR deficient (PPARα-/-) mice is influenced by other factors, including diet and genetics. Therefore, it is necessary to establish the phenotypic characterization of PPARα-/- mice prior to the obesity-related study....
282.

Determination of Roxithromycin by Liquid Chromatography/ Mass Spectrometry after Multiple-Dose Oral Administration in Broilers

Jong-hwan Lim, Byung-kwon Park, Hyo-in Yun 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2003, 제 4권 제 1호 6 35-39 (5 pages)

Jong-hwan Lim, Byung-kwon Park, Hyo-in Yun 저
...
- 1,500원
A highly sensitive and specific method for the determination of roxithromycin in broiler tissues by LC/MS was developed and validated. A dichloromethane extract of the sample was separated on C18 reversed-phase column with acetonitrile-50 mM ammonium acetate (80:20, v/v) as the mobile phase and analyzed by LC/MS via atmospheric pressure ionization/electrospray ionization interface. The limit of detection and limit of quantitation were 1 ng/g and 5 ng/g. The method has been successfully applied...
283.

The Antinociceptive and Anti-inflammatory Effect of Ethylacetate Extracts from Bang-Poong (Radix ledebouriellae) on the Freund’s Adjuvant-Induced Arthritis in Rats

Hyun-Woo Kim, Young-Bae Kwon, Tae-Won Ham, Dae-Hyun Roh, Seo-Yeon Yoon, Ho-Jae Han, Sung-Keel Kang, Hye-Jung Lee, Woung-Chon Mar 대한수의학회 Journal of Veterinary Science 7 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 4호 13 343-349 (7 pages)

Hyun-Woo Kim, Young-Bae Kwon, Tae-Won Ham, Dae-Hyun Roh, Seo-Yeon Yoon, Ho-Jae Han, Sung-Keel Kang, Hye-Jung Lee, Woung-Chon Mar 저
...
- 3,000원
In this study, we aimed to determine the antinociceptive and/or anti-inflammatory effect of Bang-Poong (BP, Radix Ledebouriellae) on Freund's adjuvant-induced arthritis in rats. Traditionally, BP has been used to treat several inflammatory diseases such as arthritis. Whole BP is extracted into two fractions that were ethylacetate and hexane-soluble fractions. Adult Sprague-Dawley rats (n=30, 130-150 g) were subcutaneously administered by the Freund's complete adjuvant (FCA) into the plantar...
284.

Simultaneous Determination of Various Macrolides by Liquid Chromatography/Mass Spectrometry

Youn-Hwan Hwang, Jong-Hwan Lim, Byung-Kwon Park and Hyo-In Yun 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 2호 7 103-108 (6 pages)

Youn-Hwan Hwang, Jong-Hwan Lim, Byung-Kwon Park and Hyo-In Yun 저
...
- 3,000원
Macrolides are frequently used in veterinary medicine as therapeutic and preventive agents for various diseases. It is difficult to determine macrolides simultaneously with conventional methods due to their similar structures. A simultaneous analysis for erythromycin, roxithromycin, tiamulin and tylosin with LC/MS has been developed. Separation was performed on C18 reversed phase column. Mobile phase was gradiently flowed with 10 mM ammonium acetate and methanol. The mass spectrometer was run in...
285.

Lack of bioequivalence of two oxytetracycline formulations in the rabbit

Y. J. Kim, W. Chong, S. D. Kim, S. K. Han, P. D. Ryu 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 1호 5 25-30 (6 pages)

Y. J. Kim, W. Chong, S. D. Kim, S. K. Han, P. D. Ryu 저
...
- 3,000원
and C(max) of test product to those of reference product was 65.4% and 60.0%, respectively. The ranges of AUC and C(max) of test drug compared to those of reference drug under 90% confidence limits were 27 104% and 28 91.5%, respectively. The results of statistical analysis indicate that the two pivotal pharmacokinetic parameters, AUC and C(max) of test product are not within the 20% of those of the reference, suggesting that the test OTC is not bioequivalent to the reference OTC.
286.

Therapeutic effect of bee venom in sows with hypogalactia syndrome postpartum

Seok-Hwa Choi, Seong-Soo Kang 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 2호 9 121-124 (4 pages)

Seok-Hwa Choi, Seong-Soo Kang 저
...
- 1,500원
intramuscularly injected with a standard dosage of penicillin G (400,000 IU/head) once a day for 3 consecutive days. At post-treatment, 85.0% of the drug-treated control and 90.9% of the bee venomtreated group recovered from hypogalactia syndrome. The advantages of apitherapy were that the patients did not have stress because they were not restrained for a long period. The result suggested that apitherapy using bee venom is an effective treatment for sows with hypogalactia syndrome postpartum.
287.

Tetracycline residue levels in cattle meat from Nairobi salughter house in Kenya

F. K. Muriuki, W. O. Ogara, F. M. Njeruh, E. S. Mitema 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 2호 5 97-101 (5 pages)

F. K. Muriuki, W. O. Ogara, F. M. Njeruh, E. S. Mitema 저
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- 1,500원
Two hundred and fifty beef samples were collected from five slaughterhouses in and around the city of Nairobi. The beef animals were sourced from various parts of the country. Samples of 50-100 grams were collected randomly from the liver, kidney and muscle of different beef carcasses. The samples collected were processed using multiresidue analytical methods that included liquid-gas partitioning and set-pat C18 cartridges chromatographic clean up. Chlortetracycline and oxytetracycline detection...
288.

Effect of fever on pharmacokinetics and dosage regimen of intramuscularly administered amikacin in goats

A. K. Agrawal, S. D. Singh, C. Jayachandran 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 2호 4 91-96 (6 pages)

A. K. Agrawal, S. D. Singh, C. Jayachandran 저
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- 3,000원
method in normal and experimentally induced febrile goats revealed that the plasma drug concentrations were significantly higher in febrile condition at most of the time intervals. Various pharmacokinetic parameters like t(1/2), AUC, AUMC, MRT and Vd(area) were significantly higher whereas total body clearance (Cl(B)) was significantly lower in febrile goats as compared to normal goats. Absorption half-life (t(1/2) ka) value differed non-significantly. For maintaining mean therapeutic level of 2...
289.

Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis

Woo-song Ha, Chi-kyeong Kim, Seung-hee Song, Chung-boo Kang 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 1호 9 53-58 (6 pages)

Woo-song Ha, Chi-kyeong Kim, Seung-hee Song, Chung-boo Kang 저
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- 3,000원
With the aim of establishing bio-indices for the development of multistep hepatotumorigenesis, rats were fed water containing 0.01% diethylnitrosamine (DEN) ad libitum for 13 weeks. This treatment with DEN only made it possible to induce hepatic tumors in 100%. After the DEN administration, several clinical symptoms were observed including minor behavioral changes, brittleness of hair and a decrease in water and food intake. The concentration of total serum protein and albumin in all treated...
290.

Flow cytometric evaluation on the age-dependent changes of testicular DNA contents in rats

Chang Yong Yoon, Choong Man Hong, Yong-Yeon Cho, Ji Young Song, I Jin Hong, Dae Hyun Cho, Beom Jun Lee, Hee Jong Song, Cheol Kyu 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 1호 7 43-46 (4 pages)

Chang Yong Yoon, Choong Man Hong, Yong-Yeon Cho, Ji Young Song, I Jin Hong, Dae Hyun Cho, Beom Jun Lee, Hee Jong Song, Cheol Kyu 저
...
- 1,500원
An age-dependent cellular change of DNA contents in the testis of Sprague-Dawley rats was investigated by flow-cytometric method. Testicular cell suspensions at the age of 4, 5, 6, 7, 8, 10, 12, 16 and 26 weeks were prepared and stained with propidium iodide. The relative proportions in the number of mature and immature haploid (1n), diploid (2n), S-phase and tetraploid (4n) cells were calculated. The proportion in the number of mature haploid cells was sharply increased to the age of 10 weeks...

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