자료유형
발행기관
- 대한신경정신의학회(72)
- 대한생리학회-대한약리학회(30)
- 대한약리학회(25)
- 우리말학회(18)
- 대한생리학회(13)
- 한국탄소학회(10)
- 대한소아치과학회(6)
- 대한수의학회(4)
- 대한치과보존학회(4)
- 한국기초간호학회(4)
- 대한신경계작업치료학회(3)
- 한국식물병리학회(3)
- 대한전기학회(2)
- 대한화학회(2)
- 한국복합재료학회(2)
- 대한고령친화산업학회(1)
- 대한기계학회(1)
- 대한치과이식임플란트학회(1)
- 생화학분자생물학회(1)
- 선박안전기술공단(1)
- 한국경호경비학회(1)
- 한국광고PR실학회(1)
- 한국구비문학회(1)
- 한국발달지원학회(1)
- 한국보훈학회(1)
- 한국센서학회(1)
- 한국습지학회(1)
- 한국어업기술학회(1)
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- 한국화재소방학회(1)
간행물
- 신경정신의학(72)
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(30)
- 대한약리학잡지(25)
- 우리말연구(18)
- 대한생리학회지(13)
- CARBON LETTERS(10)
- 대한소아치과학회지(6)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(4)
- 대한치과보존학회지(4)
- THE PLANT PATHOLOGY JOURNAL (3)
- 재활치료과학(3)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(2)
- 대한수의학회 학술대회발표집(2)
- 복합재료 : 한국복합재료학회지(2)
- BMB REPORTS(1)
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY(1)
- JOURNAL OF DENTAL IMPLANT RESEARCH(1)
- 광고PR실학연구(1)
- 구비문학연구(1)
- 대한고령친화산업학회지(1)
- 대한기계학회론문집. TRANSACTIONS OF THE KOREAN SOCIETY OF MECHANICAL ENGINEERS. A. A(1)
- 대한화학회지(1)
- 발달지원연구(1)
- 선박안전(1)
- 센서학회지(1)
- 시큐리티연구(1)
- 열환경공학(1)
- 전기학회논문지. THE TRANSACTIONS OF THE KOREAN INSTITUTE OF ELECTRICAL ENGINEERS. B, 전기기기 및 에너지변환시스템부문(1)
- 전기학회논문지= THE TRANSACTIONS OF THE KOREAN INSTITUTE OF ELECTRICAL ENGINEERS(1)
- 조형교육(1)
- 중국학논총(1)
- 한국보훈논총(1)
- 한국습지학회지(1)
- 한국어업기술학회지(1)
- 한국통신학회논문지(1)
- 한국항공우주학회지(1)
- 한국화재-소방학회지(1)
전체 선택해제
총 217건 검색
본문검색 결과만 보기
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Suppression of Autophagy and Activation of Glycogen Synthase Kinase 3beta Facilitate the Aggregate Formation of Tau
Song-InKim, Won-KiLee, Sang-SooKang, Sue-YoungLee, Myeong-JaJeong, HeeJaeLee, Sung-SooKim, GallV.W.Johnson, WanjooChun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.2 6 107-114 (8 pages)
Neurofibrillary tangle (NFT) is a characteristic hallmark of Alzheimer's disease. GSK3Ղ has been reported to play a major role in the NFT formation of tau. Dysfunction of autophagy might facilitate the aggregate formation of tau. The present study examined the role of GSK3Ղ-mediated phosphorylation of tau species on their autophagic degradation. We transfected wild type tau (T4), caspase-3-cleaved tau at Asp421 (T4C3), or pseudophosphorylated tau at Ser396/Ser404 (T4-2EC) in the... -
Antinociception Effect and Mechanisms of Campanula Punctata Extract in the Mouse
Soo-HyunPark, Yun-BeomSim, Soon-SungLim, Jin-KyuKim, Jin-KooLee, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 6 285-289 (5 pages)
In the present study, the antinociceptive profiles of Campanula punctata extract were examined in ICR mice. The Campanula punctata contain a large dose of saponin. Campanula punctata extract administered orally (200 mg/kg) showed an antinociceptive effect as measured by the tail-flick and hot-plate tests. In addition, Campanula punctata extract attenuated the writhing numbers in the acetic acid-induced writhing test. Furthermore, the cumulative nociceptive response time for intrathecal (i.t.)... -
Modulation of Presynaptic GABA Release by Oxidative Stress in Mechanically-isolated Rat Cerebral Cortical Neurons
Eu-TeumHahm, Jung-WooSeo, JinyoungHur, Young-WukCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 2 127-132 (6 pages)
Reactive oxygen species (ROS), which include hydrogen peroxide (H2O2), the superoxide anion (O2−·), and the hydroxyl radical (OH·), are generated as by-products of oxidative metabolism in cells. The cerebral cortex has been found to be particularly vulnerable to production of ROS associated with conditions such as ischemia-reperfusion, Parkinson's disease, and aging. To investigate the effect of ROS on inhibitory GABAergic synaptic transmission, we examined the electrophysiological... -
Influence of SKF81297 on Catecholamine Release from the Perfused Rat Adrenal Medulla
Deok-HoChoi, Jong-HeeCha, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.5 6 197-206 (10 pages)
The aim of the present study was to investigate the effects of 6-chloro-7,8-dihydroxy-1-phenyl-2,3, 4,5-tetrahydro-1H-3-benzazepine (SKF81297), a selective agonist of dopaminergic D1 receptor, on the secretion of catecholamines (CA) evoked by cholinergic stimulation and membrane-depolarization in the isolated perfused rat adrenal gland, and also to elucidate the mechanism involved. SKF81297 (10∼100μM) perfused into an adrenal vein for 60 min produced dose- and time-dependent inhibition of CA... -
Effects of Zinc on Spontaneous Miniature GABA Release in Rat Hippocampal CA3 Pyramidal Neurons
Byung-JuChoi, Il-SungJang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.2 1 59-64 (6 pages)
The effects of Zn2 on spontaneous glutamate and GABA release were tested in mechanically dissociated rat CA3 pyramidal neurons which retained functional presynaptic nerve terminals. The spontaneous miniature excitatory and inhibitory postsynaptic currents (mEPSCs and mIPSCs, respectively) were pharmacologically isolated and recorded using whole-cell patch clamp technique under voltage-clamp conditions. Zn2 at a lower concentration (30μM) increased GABAergic mIPSC frequency without... -
Dopamine Modulates Corticostriatal Synaptic Transmission through Both D1 and D2 Receptor Subtypes in Rat Brain
HyunHoLee, SeJoonChoi, Ki-JungKim, HyeongSeokCho, SeongYunKim, Ki-WugSung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.5 2 263-268 (6 pages)
Striatum has important roles in motor control, habitual learning and memory. It receives glutamatergic inputs from neocortex and thalamus, and dopaminergic inputs from substantia nigra. We examined effects of dopamine (DA) on the corticostriatal synaptic transmission using in vitro extracellular recording technique in rat brain corticostriatal slices. Synaptic responses were elicited by stimulation of cortical glutamatergic inputs on the corpus callosum and recorded in the dorsal striatum.... -
Mechanism of Leptin-Induced Potentiation of Catecholamine Secretion Evoked by Cholinergic Stimulation in the Rat Adrenal Medulla
Dong-YoonLim, Deok-HoChoi, Moo-JinKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.4 9 227-235 (9 pages)
The aim of the present study was to examine the effect of leptin on CA release from the isolated perfused model of the rat adrenal gland, and to establish its mechanism of action. Leptin (1∼100 ng/ml), when perfused into an adrenal vein of the rat adrenal gland for 60 min, enhanced a dose-dependently the secretory responses of CA evoked by ACh (5.32⁓103 M), DMPP (104 M) and McN-A-343 (104 M), although it alone has weak effect on CA secretion. However, it did not... -
Influence of Bradykinin on Catecholamine Release from the Rat Adrenal Medulla
Dong-YoonLim, Il-HwanKim, Gwang-MoonNa, Moo-JinKang, Ok-MinKim, Deok-HoChoi, Young-WooKi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 7 231-238 (8 pages)
The present study was undertaken to investigate the effect of bradykinin on secretion of catecholamines (CA) evoked by stimulation of cholinergic receptors and membrane depolarization from the isolated perfused model of the rat adrenal glands, and to elucidate its mechanism of action. Bradykinin (3⁓108 M) alone produced a weak secretory response of the CA. however, the perfusion with bradykinin (3⁓108 M) into an adrenal vein of the rat adrenal gland for 90 min enhanced... -
Effects of γ-Aminobutyric Acid on Intrinsic Cholinergic Action in Exocrine Secretion of Isolated, Perfused Rat Pancreas
YongDeukPark, HyungSeoPark, ZhengYunCui, HyoungJinPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 8 169-174 (6 pages)
γ-Aminobutyric acid (GABA) has been reported to enhance exocrine secretion evoked not only by secretagogues but also by intrinsic neuronal excitation in the pancreas. The pancreas contains cholinergic neurons abundantly that exert a stimulatory role in exocrine secretion. This study was undertaken to examine effects of GABA on an action of cholinergic neurons in exocrine secretion of the pancreas. Intrinsic neurons were excited by electrical field stimulation (EFS; 15 V, 2 msec, 8 Hz, 45 min)... -
Mechanism of L-NAME-Resistant Endothelium-Dependent Relaxation Induced by Acetylcholine in Rabbit Renal Artery
DongSooYeon, DuckSunAhn, Young-HoLee, SeongChunKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 5 463-469 (7 pages)
In the rabbit renal artery, acetylcholine (ACh, 1 nM∼10μM) induced endothelium-dependent relaxation of arterial rings precontracted with norepinephrine (NE, 1μM) in a dose-dependent manner. NG-nitro- L-arginine (L-NAME, 0.1 mM), an inhibitor of NO synthase, or ODQ (1μM), a soluble guanylate cyclase inhibitor, partially inhibited the ACh-induced endothelium-dependent relaxation. The ACh-induced relaxation was abolished in the presence of 25 mM KCl and L-NAME. The cytochrome P450 inhibitors,...
