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전체 선택해제
총 329건 검색
본문검색 결과만 보기
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Relative biological effectiveness of fast neutrons for apoptosis in mouse hair follicles
Hae-June Lee, Sung-Ho Kim* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 4 335-340 (6 pages)
This study compared the effects of high linear energy transfer (LET) fast neutrons on the induction of apoptosis in the hair follicles of ICR mice with those of low LET Co ■-rays. The changes that occurred from 0 to 24 h after exposing the mice to either 2 Gy of ■-rays (2 Gy/min) or 0.8 Gy of neutrons (94 mGy/min, 35 MeV) were examined. The maximum frequency was found at 12 h (■- rays) or 8 h (neutrons) after irradiation. The mice that received 0-8 Gy of ■-rays or 0-1.6 Gy of neutrons were... -
The micronucleus frequency in cytokinesis-blocked lymphocytes of cattle in the vicinity of a nuclear power plant
Hae-June Lee, Chang-Mo Kang, Se-Ra Kim, Jong-Choon Kim, Chun-Sik Bae, Ki-Seok Oh, Sung-Kee Jo, Tae-Hwan Kim, Jong-Sik Jang, Sung 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 2호 3 117-120 (4 pages)
Cytogenetic and hematological analyses were performed on the peripheral blood lymphocytes (PBLs) obtained from Korean native cattle bred in the vicinity of three nuclear power plants (Wolsong, Uljin and Yeonggwang) and in a control area. The micronucleus (MN) rates for the cattle from the Wolsong, Uljin and Yeonggwang nuclear power plants and for the control area were 9.87 ± 2.64, 8.90 ± 3.84, 9.20 ± 3.68 and 9.60 ± 3.91 per 1,000 cytokinesis-blocked lymphocytes, respectively. The apparent... -
Radioprotective effects of an acidic polysaccharide of Panax ginseng on bone marrow cells
Hyun-Ji Kim, Mi-Hyoung Kim, Yun-Young Byon, Jae Woo Park, Youngheun Jee, Hong-Gu Joo 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 6 39-44 (6 pages)
An acidic polysaccharide of Panax ginseng (APG), so called ginsan is known to have important immunomodulatory activities. It was recently reported that APG has radioprotective effects in mice but the detailed mechanism was not fully elucidated. This study examined the effects of APG on bone marrow cells (BMs). The phenotypical and functional changes in APG-treated BMs after gamma radiation were studied. The benefit of APG on BMs damaged by gamma radiation was determined by measuring the cell... -
Disposition kinetics and urinary excretion of cefpirome after intravenous injection in buffalo calves
Neetu Rajput, Vinod K. Dumka, Harpal S. Sandhu 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 4 21-25 (5 pages)
We investigated the disposition kinetics and urinary excretion of cefpirome in buffalo calves after a single intravenous administration of 10 mg/kg. Also, an appropriate dosage regimen was calculated. At 1 min after injection, the concentration of cefpirome in the plasma was 57.4 ± 0.72 μg/ml, which declined to 0.22 ± 0.01 μg/ml at 24 h. The cefpirome was rapidly distributed from the blood to the tissue compartment as shown by the high distribution coefficient values (8.67 ± 0.46/h), and by... -
Pharmacokinetics, urinary excretion and dosage regimen of levofloxacin following a single intramuscular administration in cross bred calves
Vinod K. Dumka, Anil K. Srivastava 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 5 333-337 (5 pages)
The pharmacokinetics and urinary excretion following single intramuscular administration of levofloxacin at a dose of 4 mg/kg was investigated in seven male cross bred calves. Appreciable plasma concentration of levofloxacin (0.38 ± 0.06 μg/ml) was detected at 1 min after injection and the peak plasma level of 3.07 ± 0.08 μg/ml was observed at 1 h. The drug level above MIC90 in plasma was detected up to 12 h after administration. Rapid absorption of the drug was also evident by the high... -
Characterization of Chinook head salmon embryo phenotypes of infectious salmon anemia virus by real-time RT-PCR
Khalid Munir 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 13 167-176 (10 pages)
We have previously described the development of a onetube SYBR Green real-time RT-PCR assay for the detection and quantitation of infectious salmon anemia virus (ISAV) in various biological samples. The twofold aim of the present study was to verify that the optimized SYBR Green real-time RT-PCR conditions could detect ISAV isolates of different geographic origins, and to analyze the growth patterns of the selected ISAV isolates in the Chinook head salmon embryo (CHSE) -214 cells by this assay... -
Circadian variations of serum thyroxine, free thyroxine and 3, 5, 3'triiodothyronine concentrations in healthy dogs
Woo-Pil Hoh, Tae-Ho Oh 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 1호 4 25-29 (5 pages)
This study was to determine the daily fluctuation of serum thyroxine (tT 4), free thyroxine (fT 4 ), 3, 5, 3'-triiodo- thyronine (T 3)concentrations in healthy dogs.Thyroid function of these dogs was evaluated on the basis of results of TSH response test.Samples for the measurement of serum tT 4 , fT 4 , and T3 concentrations were obtained at 3- hour intervals from 8 :00 to 20 :00.Serum tT 4 , fT 4 , and T3 concentrations were measured by the enzyme chemilu-minescent immunoassay (ECLIA).Mean T 3... -
Alteration of pharmacokinetics of oxytetracycline following oral administration of Piper longum in hens
M. Singh, C. Varshneya, R. S. Telang, A. K. Srivastava 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 3호 4 197-200 (4 pages)
The pharmacokinetic profile of orally administered oxytetracycline (10 mg/kg body weight)was studied 7 days post oral treatment of Piper longum (15 mg equivalent/kg) in White Leghorn hens (2-2.8 kg). On the day 8, oxytetracycline (OTC)was administered orally and blood samples were collected from the wing vein in heparinised vials for plasma separation at 0 (pre-treatment), 15, 30, 60, 120, 240, 360, 480 and 600 minutes post OTC administration. Plasma OTC concentrations were determined by... -
Role of mucosal mast cells in visceral hypersensitivity in a rat model of irritable bowel syndrome
Jun-Ho La, Tae-Wan Kim, Tae-Sik Sung, Hyun-Ju Kim, Jeom-Yong Kim, Il-Suk Yang 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 6 319-324 (6 pages)
The involvement of mucosal mast cells (MMC) in the pathophysiology of irritable bowel syndrome (IBS) is still controversial. We aimed to re-evaluate the role of MMC in visceral hypersensitivity associated with IBS using a rat IBS model that develops the IBS symptom after a subsidence of acetic acid-induced colitis. No significant difference in the number of MMC was observed between normal rat colon and IBS rat colon. (61.7 ±2.9/mm 2 in normal vs. 88.7 ±13.3/mm 2 in IBS, p > 0.29). However, the... -
The effects of cyclophosphamide treatment on the pathogenesis of subgroup J avian leukosis virus (ALV-J) infection in broiler chickens with Marek's disease virus exposure
Yongbaek Kim, Thomas P. Brown and Mary J. Pantin-Jackwood 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 1호 7 49-58 (10 pages)
real time RT-PCR using SYBR green I dye. The percentage of viremic chickens was significantly higher, and more chickens had high titered viremia, in the CY treated group. No neoplastic foci consistent with ALVJ infection were observed in any of the experimental chickens. The frequency and intensity of viral antigen expression determined by immunohistochemistry was significantly higher in tissues from CY treated birds than those of PBS treated chickens at 3 weeks post-infection. This study showed...
