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Spectral Analysis of Heart Rate Variability during Passive Standing after Ethanol Ingestion
HyeongJinKim, ChunDukHan, EunKyoungYang, WonJungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 9 605-613 (9 pages)
in F, in normalized units) and LF/HF (3.10⁑0.57 in NF, 3.00⁑1.08 in F) and decreased HFn powers. Ethanol ingestion increased LFn and LF/HF and decreased HFn. PS after ethanol resulted in higher LFn and LF/HF and lower HFn than the prior PS. F showed a greater and more sustained HRV change than NF after ethanol. In conclusion, PS or ethanol ingestion increased LFn and LF/HF and decreased HFn. Flushed subjects showed an accentuated HRV response to ethanol. -
Effects of Protein Kinase C Modulation on Hepatic Hemodynamics and Glucoregulation
JoongWooLee, InDeokKong, KyuSangPark, HaeSookChung, JamesPFilkins 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 5 571-578 (8 pages)
This study evaluated the effects of PKC activation using phorbol 12-myristate 13-acetate (PMA) and PKC inhibition using the isoquinoline sulfomide derivative H-7 on hemodynamics and glucoregulation in the isolated perfused rat liver. Livers were isolated from fed male Holtzman rats and perfused with Krebs Ringer bicarbonate solution under a constant flow of 50 ml/min at 35oC. Portal vein pressure, glucose and lactate concentrations in the medium and oxygen consumption rates were continuously... -
Altered Cerebral Vasomotion with Decreased CGRP Level in Pial Arteries of Spontaneously Hypertensive Rats
KwangHoLee, JaeMoonChoi, KiWhanHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 5 573-580 (8 pages)
(3⁓10-7 M) was suffused over the cortical surface, a transient increase in pial arterial diameter was observed in the SHR with high or normotensive BP. In contrast, SDR and WR showed a large increase in diameter, and the increase was sustained for over 10 minutes. In line with these results, the basal releases of CGRP-like immunoreactivity (CGRP-LI) in the isolated pial arteries from SHR with high and normotensive BP were 12.5⁑1.4 and 9.8⁑2.8 fmole/mm2/60 min (P<0.05), while... -
Ca2+ Signalling in Endothelial Cells Role of Ion Channels
BerndNilius, FelixViana, MasahiroKamouchi, CristinaFasolato, JanEggermont, GuyDroogmans 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 1 133-145 (13 pages)
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Effect of UV Irradiation and Rebamipide on the Blood Flow and Viability of Rabbit Skin Flap
Eung-JooSuh, Hyoung-ChulChoi, Uy-DongSohn, Jeoung-HeeHa, Kwang-YounLee, Won-JoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 14 581-589 (9 pages)
free radical scavenger, gradually increase the BFF. The rebamipide-induced increase in BFF was sustained at the level of the SNP-induced increase in BFF during the late period of experiment. Rebamipide increased the WMS of skin flaps and prevented the tissue necrosis in comparison with L-NAME. Based on these results, it is concluded that in rabbit skin, UVL irradiation increases the BFF by NO release, and rebamipide exerts a protective effect on the viability of ischemic skin flaps by either or... -
Effect of pH on the ATP-sensitive K+ Channel in Aortic Smooth Muscle Cells from Rats
SeHoonKim, IlSuKim, HoeSukKim, ByeongHwaJeon, SeokJongChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 11 555-563 (9 pages)
The effects of pH on K currents were investigated in single smooth muscle cells isolated from the thoracic aorta of Wistar-Kyoto rats. Whole-cell K currents were recorded in the conventional configuration of the voltage-clamp technique. Pinacidil (10uM) activated the whole-cell current and the pinacidil-activated current was completely inhibited by glibenclamide (10uM) , an inhibitor of ATP-sensitive K channel (KATP channel). Pinacidil-activated current was reversed at near... -
Two Types of Voltage-dependent Outward Potassium Currents in Smooth Muscle Cells of Rabbit Basilar Atery
TongMookKang, InsukSo, DaeYongUhm, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 15 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 7 169-183 (15 pages)
We have investigated the two types of voltage-dependent outward potassium (K) currents, i.e. delayed rectifier K current (IK(V)) and 'A-like' transient outward K current (Ito) with patch-clamp technique in single smooth muscle cells (SMCs) isolated from rabbit basilar artery, and investigated the characteristics of them. The time-courses of activation were well fitted by exponential function raised to second power (n2) in IK(v) and fourth power (n4) in Ito. The activation, inactivation and... -
한국 성인 인지기능 평가를 위한 전산화 검사도구의 개발과 표준화 과정 및 요인분석
하규섭, 권준수, 류인균, 공석원, 이동우, 윤탁 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 2002, 제 41권 제 3호 16 551-562 (12 pages)
연구목적: 인지기능의 정확한 평가가 정신과 임상에서 더욱 중요해지고 있다. 아직 한국에는 한글로 제작되고, 한국인을 대상으로 표준화된 인지기능 평가 검사집이 마련되어 있지 않다. 검사자극을 일정하게 유지 하고, 검사자에 의한 변인을 통제할 수 있으며, 전문가의 시간과 비용을 절감해 줄 수 있는 전산화 인 지기능평가 도구집을 개발하고, 개발된 인지기능평가 도구집이 인지영역의 어느 부분을 평가하는지 확인하기 위하여 본 연구를 수행하였다. 방 법: 수차례의 예비연구와 신뢰도, 타당도 검증의 과정을 거쳐 전산화... -
학령기 전 정상발달의 임상적 평가와 전반적 발달장애
대한신경정신의학회 신경정신의학 2008, 제 47권 제 5호 1 397-408 (12 pages)
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신성 고혈압쥐의 전신성 동맥계와 폐동맥계에 대한 EDRF 기능의 차이
이병호(Byung-Ho Lee), 신화섭(Hwa-Sup Shin), 허인회(In-Hoe Huh) 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 1993, 제 29권 제 2호 7 213-224 (12 pages)
급성 신성 고혈압쥐 (2-kidney, 1-ligation type)의 전신성 동맥계와 폐 동맥계에 대한 내피 의존적 혈관반응성을 규명하기 위하여, 적출 혈관 및 마취상태의 흰쥐에 대한 acetylcholine (ACh)의 혈관이완작용 및 혈압강하 작용을 측정하였다. 혈장 renin 활성(PRA)은 신동맥 결찰전 7.31 ± 0.63 ng/ml/hr A I에 비해 결찰 6 ~ 8일후에는 19 ~ 22 ng/ml/hr A I으로 유의성있게 증가하였으며, 이는 수축기혈압의 상승과 (154 ± 1.83{\rightarrow}190 ~ 215 mmHg) 일정한 상관성을 유지하였다. 신성 고혈압쥐 및 정상 혈압쥐의 흉곽...


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