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Reoxygenation Stimulates EDRF(s) Release from Endothelial Cells of Rabbit Aorta
SukHyoSuh, JaeJinHan, SungJinPark, JaiYoungChoi, JaeHoonSim, YoungChulKim, KiWhanKim* 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 4 393-404 (12 pages)
the combined treatment with nitro-L-arginine and TEA. Cytochrome P450 blocker, SKF-525A, inhibited the EDRF(s) release reversibly and endothelin antgonists, BQ 123 and BQ 788, had no effect on the release of endothelium-derived vasoactive factors. Superoxide dismutase (SOD) and catalase inhibited the EDRF(s) release from endothelial cells. From these data, it could be concluded that reoxygenation stimulates EDRF(s) release and hypoxia/reoxygenation can release not only NO but also another EDRF... -
The Effects of Sera from Amyotrophic Lateral Sclerosis Patients on Neuromuscular Transmission and Calcium Channels in Mice
HaiDunYan, JimokKim, SungJunJung, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 17 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 13 101-117 (17 pages)
Amyotrophic lateral sclerosis (ALS) is a degenerative neuromuscular disease of unknown etiology in which the upper and lower motor neurons are progressively destroyed. Recent evidences support the role of autoimmune mechanisms in the pathogenesis of ALS. This study investigated the effects of sera from ALS patients on neuromuscular transmission in phrenic nerve-hemidiaphragm preparations and on calcium currents of single isolated dorsal root ganglion (DRG) cells in mice. Mice were injected with... -
Nitric Oxide Impairs the Recovery from Hemorrhagic Hypotension in Conscious Rats
Yoon-yubParkYoung-ManLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 9 345-351 (7 pages)
The role of nitric oxide (NO) in the hemorrhagic hypotension was examined using a NO synthase inhibitor, Nω-nitro-L-arginine methyl ester (L-NAME), in conscious rats. The rats were bled at a constant rate (2 ml/kg/min) through a femoral arterial catheter until the mean arterial pressure (MAP) was reduced by 50 mmHg. We studied the responses to hemorrhage under normal condition (Control) and after the pretreatment with 3 doses of L-NAME (1.6, 8, 40 mg/kg i.v. of NOX1.6, NOX8, and NOX40,... -
Influence of the Central Benzodiazepinergic System on Peripheral Cardiovascular Regulation
Jeong-TaeKoh, Jeong-MinJu, Dong-HoShin, Han-HoCho, Bong-KyuChoi, Jae-HaKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 3 287-295 (9 pages)
Diazepam is known to have cardiovascular depressive effects through a combined action on benzodiazepinergic receptor and the GABA receptor-chloride ion channel complex. Moreover, it is known that barbiturates also have some cardiovascular regulatory effects mediated by the central GABAergic system. Therefore, this study was undertaken to delineate the regulatory actions and interactions of these systems by measuring the responses of the cardiovascular system and renal nerve activity to muscimol,... -
쥐 척수후각세포의 유해자극 반응에 대한 칼슘이온통로 차단제의 억제작용 Calcium Channel Blockers Suppress the Responses of Rat Dorsal Horn Cell to Nociceptive Input
신홍기, 강석한, 김기순, HongKeeShin, SokHanKang, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 3 625-637 (13 pages)
Calcium ions are implicated in a variety of physiological functions, including enzyme activity, membrane excitability, neurotransmitter release, and synaptic transmission, etc. Calcium antagonists have been known to be effective for the treatment of exertional angina and essential hypertension. Selective and nonselective voltage-dependent calcium channel blockers also have inhibitory action on the acute and tonic pain behaviors resulting from thermal stimulation, subcutaneous formalin injection... -
Effect of UV Irradiation and Rebamipide on the Blood Flow and Viability of Rabbit Skin Flap
Eung-JooSuh, Hyoung-ChulChoi, Uy-DongSohn, Jeoung-HeeHa, Kwang-YounLee, Won-JoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 14 581-589 (9 pages)
This study was undertaken to examine the effects of ultraviolet light (UVL) and rebamipide on the cutaneous blood flow and tissue survival on rabbit skin flap. In a random bipedicle flap, Laser Doppler Flowmetry (LDF) was employed to measure the blood flow of flap (BFF). Wound Margin Strength (WMS) measured by force transducer and Light microscophy were used for evaluation of tissue viability. Single exposure to UVL increased the BFF gradually for more than 15 hours, and decreased the... -
Effect of t-butylhydroperoxide on Na+-dependent Glutamate Uptake in Rabbit Brain Synaptosome
HyunJeLeeYongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 3 367-376 (10 pages)
The effect of an organic peroxide, t-butylhydroperoxide (t-BHP), on glutamate uptake was studied in synaptosomes prepared from cerebral cortex. t-BHP inhibited the Na+-dependent glutamate uptake with no change in the Na+-independent uptake. This effect of t-BHP was not altered by addition of Ca2+ channel blockers (verapamil, diltiazem and nifedipine) or PLA2 inhibitors (dibucaine, butacaine and quinacrine). However, the effect was prevented by iron chelators (deferoxamine and phenanthroline)... -
Combination of Electroconvulsive Therapy and Clozapine in Treatment-Resistant Schizophrenia
Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung 대한신경정신의학회 Psychiatry Investigation 7 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 13 829-835 (7 pages)
Objective_This study aimed to investigate the effectiveness and tolerability of the combination of electroconvulsive therapy (ECT) in patients with clozapine-treated schizophrenia. Methods_Patients with clozapine-treated schizophrenia during five years of pre-determined period were recruited from Electronic Medical Record. Clinical effects of acute ECT on psychotic symptoms were investigated. We also tried to identify predictive variables requiring maintenance treatment of ECT. Results_Fourteen... -
A Systematic Review and Meta-Analysis of Applicability of Web-Based Interventions for Individuals with Depression and Quality of Life Impairment
Danbi Yang, Ji-Won Hur, Yoo Bin Kwak, Sung-Won Choi 대한신경정신의학회 Psychiatry Investigation 8 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 3 759-766 (8 pages)
Objective_The purpose of this meta-analysis was to determine the applicability of web-based treatment programs for individuals with depression and quality of life impairments. Methods_We conducted database and manual searches using imprecise search-term strategy and inclusion criteria. Research published from 2005 to December 2015 was included in this study. Upon review, a total of 12 published papers on web-based intervention for individuals with depression were assessed eligible for this...


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