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321.

Changes in Vestibular Nerve Activity Following Acute Hypotension in Rats

ByungRimPark, MinSunKim, GueHyunYee, MyoungJinMoon, JaeHyoKim, YuanZheJin, YoSikKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 6 85-89 (5 pages)

ByungRimPark, MinSunKim, GueHyunYee, MyoungJinMoon, JaeHyoKim, YuanZheJin, YoSikKim 저
...
- 1,500원
The basic mechanism for the excitation of the peripheral vestibular receptors following acute hypotension induced by sodium nitroprusside (SNP) or hemorrhage was investigated in anesthetized rats. Electrical activity of the afferent vestibular nerve was measured after pretreatment with kynurenic acid, an NMDA receptor antagonist. The activity of the vestibular nerve at rest following acute hypotension induced by SNP or simulating hemorrhage was a greater increase than in control animals. The...
322.

Inhibition of NF-κB Activation Increases Oxygen-Glucose Deprivation-Induced Cerebral Endothelial Cell Death

JinuLee, ChulHoonKim, KyuDaeShim, YoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 3 65-71 (7 pages)

JinuLee, ChulHoonKim, KyuDaeShim, YoungSooAhn 저
...
- 3,000원
Increasing evidences suggest that ischemia-induced vascular damage is an integral step in the cascade of the cellular and molecular events initiated by cerebral ischemia. In the present study, employing a mouse brain endothelioma-derived cell line, bEnd.3, and oxygen-glucose deprivation (OGD) as an in vitro stroke model, the role of nuclear factor kappa B (NF-κB) activation during ischemic injury was investigated. OGD was found to activate NF-κB and to induce bEnd.3 cell death in a...
323.

Dietary Ascorbate Supplementation Reduces Oxidative Tissue Damage and Expression of iNOS in the Kidney of Streptozotocin Induced Diabetic Rats

MyungSeoupChoi, YoonYoungJang, WooSeungLee, JinHoSong, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.1 8 39-45 (7 pages)

MyungSeoupChoi, YoonYoungJang, WooSeungLee, JinHoSong, YongKyooShin 저
...
- 3,000원
Reactive oxygen species (ROS) have been suggested to be contributory factors in complications of diabetes mellitus. In the present study, we investigated the generation of superoxide, the lipid peroxide level measured as thiobarbituric acid reactive substances, the vasorelaxation of isolated thoracic aorta and the iNOS expression in kidney of streptozotocin induced diabetic rats. Sprague Dawley rats were divided into four groups: control, ascorbate (400 mg/kg rat weight daily in drinking water),...
324.

Characterization of Intermediate Conductance K+ Channels in Submandibular Gland Acinar Cells

Sung-ManCho, ZhengGenPiao, YoonBaeKim, Joong-SooKim, KyungpyoPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.6 5 305-309 (5 pages)

Sung-ManCho, ZhengGenPiao, YoonBaeKim, Joong-SooKim, KyungpyoPark 저
...
- 1,500원
There are some evidences that K⁢ efflux evoked by muscarinic stimulation is not mainly mediated by large conductance K⁢ (BK) channels in salivary gland. In this experiment, we therefore characterised non BK channels in rat submandibular gland acinar cells and examined the possibility of agonist effect on this channel using a patch clamp technique. Two types of K⁢ channels were observed in these cells. BK channels were observed in 3 cells from total 6 cells and its average...
325.

Effects of Kanagawa Hemolysin on Blood Pressure and Arterial Tone in Rats

YoungMoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.4 8 225-233 (9 pages)

YoungMoonKim 저
...
- 3,000원
Kanagawa hemolysin (KH), an exotoxin produced from Kanagawa phenomenon-positive Vibrio parahemolyticus, has been shown to possess various biological activities including hemolysis, enterotoxicity, cytotoxicity, and cardiotoxicity. The aim of this study was to investigate the effect of KH on the cardiovascular system and its mechanism, employing in vivo and in vitro experiments of the rat. Intracerebroventricular (icv) administration of 100 mHU KH produced a marked and continuous pressor effect...
326.

Neuronal Activity of the Vestibular Nuclei Following Acute Hypotension in Rats

ByungRimPark, MinSunKim, KumHyunBaik, MoonYoungLee, MyungAeChoi, JaeHyoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.4 5 199-206 (8 pages)

ByungRimPark, MinSunKim, KumHyunBaik, MoonYoungLee, MyungAeChoi, JaeHyoLee 저
...
- 3,000원
The role of peripheral vestibular receptors in acute hypotension was investigated in anesthetized rats. Acute hypotension was induced by either intravenous infusion of sodium nitroprusside (SNP) or by experimental hemorrhage, and electrical activity and expression of cFos-like immunoreactive (cFL) protein were measured in the medial vestibular nuclei (MVN). Blood pressure decreased proportionately to the does of intravenous SNP and to the volume of the hemorrhage. Blood pressure decreased 10,...
327.

Upregulation of Renal Renin-Angiotensin System in Rats with Adriamycin-Induced Nephrosis

SooWanKim, JongUnLee, Sang-WoongHan, JunHoRyu, YoonWhaOh, NamHoKim, KiChulChoi, Ho-JungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.2 10 127-130 (4 pages)

SooWanKim, JongUnLee, Sang-WoongHan, JunHoRyu, YoonWhaOh, NamHoKim, KiChulChoi, Ho-JungKim 저
...
- 1,500원
The present study was aimed to investigate whether the adriamycin-induced nephrosis is associated with an altered regulation of local renin-angiotensin system (RAS) in the kidney. Rats were subjected to a single injection of adriamycin (2 mg/kg body weight, IV) and kept for 6 weeks to allow the development of nephrosis. They were then divided into two groups, and supplied with and without cilazapril, an angiotensin converting enzyme (ACE) inhibitor, in drinking water (100 mg/l) for additional 6...
328.

Lipopolysaccharide Inhibits Proliferation of the Cultured Vascular Smooth Muscle Cells by Stimulating Inducible Nitric Oxide Synthase and Subsequent Activation of Guanylate Cyclase

HyoungChulChoi, SangGonLee, JongHoKim, JooYoungKim, UyDongSohn, JeoungHeeHa, KwangYounLee, WonJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.4 7 343-351 (9 pages)

HyoungChulChoi, SangGonLee, JongHoKim, JooYoungKim, UyDongSohn, JeoungHeeHa, KwangYounLee, WonJoonKim 저
...
- 3,000원
This study was undertaken to investigate the mechanism of lipopolysaccharide (LPS) and nitric oxide (NO) as a regulator of vascular smooth muscle cell (VSMC) proliferation. VSMC was primarily cultured from rat aorta and confirmed by the immunocytochemistry with anti-smooth muscle myosin antibody. The number of viable VSMCs were counted, and lactate dehydrogenase (LDH) activity was measured to assess the degree of cell death. Concentrations of nitrite in the culture medium were measured as an...
329.

The Alteration of Ca2+-activated K+ Channels in Coronary Arterial Smooth Muscle Cells Isolated from Isoproterenol-induced Cardiac Hypertrophy in Rabbit

NariKim, JinHan, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 5 147-156 (10 pages)

NariKim, JinHan, EuiyongKim 저
...
- 3,000원
It has been proposed that Ca2⁢-activated K⁢ (KCa) channels play an essential role in vascular tone. The alterations of the properties of coronary KCa channels have not been studied as a possible mechanism for impaired coronary reserve in cardiac hypertrophy. The present studies were carried out to determine the properties of coronary KCa channels in normal and hypertrophied hearts. These channels were measured from rabbit coronary smooth muscle cells using a patch clamp technique....
330.

The Hyperthermic Effect of Nitric Oxide in Central Nervous System

Jae-KyungJung, UyDongSohn, Seok-YongLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.1 13 93-98 (6 pages)

Jae-KyungJung, UyDongSohn, Seok-YongLee 저
...
- 3,000원
The precise mechanism of set-point regulation in hypothalamus was not elucidated. Nitric oxide synthases(NOS) were detected in hypothalamus, however, the roles of NO in hypothalamus was not fully studied. So, we tested the effects of NO on body temperature because preoptic-anterior hypothalamus was known as the presumptive primary fever-producing site. NO donor sodium nitroprusside (SNP, 4 nmol, i.c.v.) elicited marked febrile response, and this febrile response was completely blocked by...

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