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331.

Temporal Changes in Neuronal Activity of the Bilateral Medial Vestibular Nuclei Following Unilateral Labyrinthectomy in Rats

ByungRimPark, MoonYoungLee, MinSunKim, SungHoLee, HanJoNa, NamYongDoh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 4 481-490 (10 pages)

ByungRimPark, MoonYoungLee, MinSunKim, SungHoLee, HanJoNa, NamYongDoh 저
...
- 3,000원
To investigate the changes in the responses of vestibular neurons with time during vestibular compensation, the resting activity and dynamic responses of type I and II neurons in the medial vestibular nuclei to sinusoidal angular acceleration were recorded following unilateral labyrinthectomy (ULX) in Sprague-Dawley rats. The unitary extracellular neuronal activity was recorded from the bilateral medial vestibular nuclei with stainless steel microelectrodes of 3∼5 MΩ before ULX, and 6, 24,...
332.

The Role of Somatostatin in Nociceptive Processing of the Spinal Cord in Anesthetized Cats

SungJunJung, JooMinPark, JunHoLee, JihyeLee, SangJeongKim, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 1 365-373 (9 pages)

SungJunJung, JooMinPark, JunHoLee, JihyeLee, SangJeongKim, JunKim 저
...
- 3,000원
Somatostatin (SOM) is one of the major neuropeptides in dorsal root ganglion cells, but its role in spinal nociceptive process has not been well known. In present study we aimed to investigate the effect of SOM on the response of dorsal horn neurons to the various types of peripheral nociceptive stimuli in anesthetized cats. Using carbon-filament microelectrode, the single cell activities of wide dynamic range neurons were recorded from the lumbosacral enlargement after noxious mechanical...
333.

Effect of the Inhibition of Phospholipase A2 in Generation of Free Radicals in Intestinal Ischemia/Reperfusion Induced Acute Lung Injury

YoungManLee, Yoon-yubPark, TeoanKim, HyunG.Cho, YoonJeongLee, JohnE.Repine 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 4 263-273 (11 pages)

YoungManLee, Yoon-yubPark, TeoanKim, HyunG.Cho, YoonJeongLee, JohnE.Repine 저
...
- 4,000원
The role of phospholipase A2 (PLA2) in acute lung leak induced by intestinal ischemia was investigated in association with neutrophilic respiratory burst. To induce lung leak, we generated intestinal ischemia for 60 min prior to the 120 min reperfusion by clamping superior mesenteric artery in Sprague-Dawley rats. Acute lung leak was confirmed by the increased lung leak index and protein content in bronchoalveolar fluid. These changes were inhibited by mepacrine, the non-specific PLA2...
334.

Magnesium Suppresses the Responses of Dorsal Horn Cell to Noxious Stimuli in the Rat

HongKeeShin, JinHyukKim, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 1 237-244 (8 pages)

HongKeeShin, JinHyukKim, KeeSoonKim 저
...
- 3,000원
Magnesium ion is known to selectively block the N-methyl-D-aspartate (NMDA)-induced responses and to have anticonvulsive action, neuroprotective effect and antinociceptive action in the behavioral test. In this study, we investigated the effect of Mg2⁢ on the responses of dorsal horn neurons to cutaneous thermal stimulation and graded electrical stimulation of afferent nerves as well as to excitatory amino acids and also elucidated whether the actions of Ca2⁢ and Mg2⁢ are...
335.

Calcium Modulates Excitatory Amino Acid (EAA)- and Substance P-induced Rat Dorsal Horn Cell Responses

HongKeeShin, SokHanKang, InDukChung, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 5 35-45 (11 pages)

HongKeeShin, SokHanKang, InDukChung, KeeSoonKim 저
...
- 4,000원
Excitatory amino acid (EAA) and substance P (SP) have been known to be primary candidates for nociceptive neurotransmitter in the spinal cord, and calcium ions are implicated in processing of the sensory informations mediated by EAA and SP in the spinal cord. In this study, we examined how Ca2⁢ modified the responses of dorsal horn neurons to single or combined iontophoretical application of EAA and SP in the rat. All the LT cells tested responded to kainate, whereas about 55% of low...
336.

Effects of Angiotensin Converting Enzyme Inhibition on Gene Expression of the Renin-Angiotensin System in Rats

YoungRaeLee, MiYoungLee, WoonJungKim, WonJungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 14 771-778 (8 pages)

YoungRaeLee, MiYoungLee, WoonJungKim, WonJungLee 저
...
- 3,000원
To investigate interaction of angiotensin converting enzyme (ACE) inhibitor with local tissue renin- angiotensin system (RAS), changes in gene expression of the RAS components in various tissues in response to chronic administration of an ACE inhibitor, enalapril, were examined in Sprague-Dawley male rats. Enalapril was administered in their drinking water (3∼4 mg/day) over 8 wk. Plasma and renal ACE activity increased significantly after 4 and 8 wk of enalapril treatment. Renin levels of the...
337.

Modulation of ATP-Induced Activation of the Muscarinic K+ Channel Activity by Protein Kinase C

Yang-MiKim, Hong-KiPark, Jae-HeeHan, Choon-OkPark, Seong-GeunHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 11 743-753 (11 pages)

Yang-MiKim, Hong-KiPark, Jae-HeeHan, Choon-OkPark, Seong-GeunHong 저
...
- 4,000원
The atrial acetylcholine-activated K⁢ (KACh) channel is gated by the pertussis toxin-sensitive inhibitory G (GK) protein. Earlier studies revealed that ATP alone can activate the KACh channel via transphosphorylation mediated by nucleoside-diphosphate kinase (NDPK) in atrial cells of rabbit and guinea pig. This channel can be activated by various agonists and also modulated its function by phosphorylation. ATP-induced KACh channel activation (AIKA) was maintained in the presence of the...
338.

Dopaminergic Inhibition of Dorsal Horn Cell Activity in the Cat

KyungChulKim, HongKeeShin, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 2 661-670 (10 pages)

KyungChulKim, HongKeeShin, KeeSoonKim 저
...
- 3,000원
Dopamine has been generally known to exert antinociceptive action in behavioral pain test, such as tail flick and hot plate test, but there appears to be a great variance in the reports on the antinociceptive effect of dopamine depending on the dosage and route of drug administration and type of animal preparation. In the present study, the effects of dopamine on the responses of wide dynamic range (WDR) cells to mechanical, thermal and graded electrical stimuli were investigated, and the...
339.

Angiotensin-Converting Enzyme Gene Polymorphism is not Associated with Myocardial Infarction in Koreans

SeokChaiDong-RyulSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 13 645-650 (6 pages)

SeokChaiDong-RyulSohn 저
...
- 3,000원
typed by polymerase chain reaction. The I allelic frequency of ACE gene in Korean subjects was irrelavant to myocardial infarction (patients, 65%; control subjects 66%), as was true with the D allele. When compared with other populations, the frequency of D allele in Koreans (0.34) was lower than that in Caucasians, and was close to that of other Oriental populations. The data suggest that the ACE gene polymorphism is not an independent genetic risk factor for myocardial infarction in Koreans.
340.

Effect of the Inhibition of PLA2 on Oxidative Lung Injury Induced by Interleukin-1㄁

YoungManLee, HyunGugCho, Yoon-YubPark, Jong-KiKim, YoonJeongLee, Won-HarkPark, TeoanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 10 617-628 (12 pages)

YoungManLee, HyunGugCho, Yoon-YubPark, Jong-KiKim, YoonJeongLee, Won-HarkPark, TeoanKim 저
...
- 4,100원
gamma glutamyltransferase (GGT), and ultrastructural changes were examined. IL-1 increased the level of phospholipid in the bronchoalveolar lavage (BAL) fluid, which seemed to be caused by abnormal, pathological release of lamellar bodies into the alveolar lumen. Mepacrine recovered the amount of surfactant up to control level. IL-1 decreased GGT activity, while mepacrine restored it. In ultrastructural study, when treated with IL-1, marked necroses of endothelial cells and type II pneumocytes...

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