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331.

Electrophysiological and Morphological Classification of Inhibitory Interneurons in Layer II/III of the Rat Visual Cortex

Duck-JooRhie, HoYoungKang, GyeongRyulRyu, Myung-JunKim, ShinHeeYoon, SangJuneHahn, DoSikMin, Yang-HyeokJo, Myung-SukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 5 317-323 (7 pages)

Duck-JooRhie, HoYoungKang, GyeongRyulRyu, Myung-JunKim, ShinHeeYoon, SangJuneHahn, DoSikMin, Yang-HyeokJo, Myung-SukKim 저
...
- 3,000원
Interneuron diversity is one of the key factors to hinder understanding the mechanism of cortical neural network functions even with their important roles. We characterized inhibitory interneurons in layer II/III of the rat primary visual cortex, using patch-clamp recording and confocal reconstruction, and classified inhibitory interneurons into fast spiking (FS), late spiking (LS), burst spiking (BS), and regular spiking non-pyramidal (RSNP) neurons according to their electrophysiological...
332.

SM709, Ingredient of Antimelanogenic Bamboo Extract, Blocks Endothelin-1-induced [Ca2+]i Increase in Human Melanocytes

Shin-HeeKim, Ki-MuLee, HyoShinKim, GyuSeungLee, ByeongHwaJeon, KwangJinKimJinBongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 4 311-316 (6 pages)

Shin-HeeKim, Ki-MuLee, HyoShinKim, GyuSeungLee, ByeongHwaJeon, KwangJinKimJinBongPark 저
...
- 3,000원
Endothelins secreted from keratinocytes are intrinsic mitogens and melanogens of human melanocytes in UVB-induced hyperpigmentation. To elucidate the cellular mechanism of antimelanogenic activity of bamboo extract, the effects of three ingredients of bamboo extract on endothelin 1 (ET-1)-induced Ca2⁢ mobilization were investigated in cultured human melanocytes. ET-1 receptors in human melanocytes were characterized by using specific antagonist, and ET-1 was found to increase intracellular...
333.

Inhibitory Modulation of 5-Hydroxytryptamine on Corticostriatal Synaptic Transmission in Rat Brain Slice

SeJoonChoi, WonSoonChung, Ki-JungKim, Ki-WugSung, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 1 295-301 (7 pages)

SeJoonChoi, WonSoonChung, Ki-JungKim, Ki-WugSung, 저
...
- 3,000원
Striatum plays a crucial role in the movement control and habitual learning. It receives an information from wide area of cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT) input from raphe nuclei. In the present study, the effects of 5-HT to modulate synaptic transmission were studied in the rat corticostriatal brain slice using in vitro extracellular recording technique. Synaptic responses were evoked by stimulation of cortical glutamatergic inputs on the corpus...
334.

Inhibitory Effect of Esculetin on the Inducuble Nitric Oxide Synthase Expression in TNF-stimulated 3T3-L1 Adipocytes

Jeong-YehYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.5 7 283-287 (5 pages)

Jeong-YehYang 저
...
- 1,500원
While nitric oxide (NO) produced by inducible nitric oxide synthase (iNOS) is beneficial for host survival, it is also detrimental to the host. Thus, regulation of iNOS gene expression may be an effective therapeutic strategy for the prevention of unwanted reactions at various pathologic conditions. During the screening process for the possible iNOS regulators, we observed that esculetin is a potent inhibitor of cytokine-induced iNOS expression. The treatment of 3T3-L1 adipocytes with the tumor...
335.

CD40 Activation Protects Dendritic Cells from Anticancer Drug-Induced Apoptosis

Jae-YeonJunHong-GuJoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.5 2 255-259 (5 pages)

Jae-YeonJunHong-GuJoo 저
...
- 1,500원
Dendritic cells (DCs) play a critical role in various immune responses involving CD4⁢ T cells and have been used to generate anti-tumor immunity. Chemotherapy induces severe side effects including immunosuppression in patients with cancer. Although immunosuppression has been studied, the effects of anticancer drugs on DCs are not fully determined. In this study, we demonstrated that CD40 activation strongly protected DCs from 5-fluorouracil (5-FU) or mitomycin C-induced apoptosis. DC-...
336.

Salicylate Regulates Cyclooxygenase-2 Expression through ERK and Subsequent NF-κB Activation in Osteoblasts

Han-JungChae, Jun-KiLee, Joung-OukByun, Soo-WanChae, Hyung-RyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 8 239-246 (8 pages)

Han-JungChae, Jun-KiLee, Joung-OukByun, Soo-WanChae, Hyung-RyongKim 저
...
- 3,000원
The expression of cyclooxygenase-2 (COX-2) is a characteristic response to inflammation and can be inhibited with sodium salicylate. TNF-α plus IFN-γ can induce extracellular signal-regulated kinase (ERK), IKK, IκB degradation and NF-κB activation. The inhibition of the ERK pathway with selective inhibitor, PD098059, blocked cytokine-induced COX-2 expression and PGE2 release. Salicylate treatment inhibited COX-2 expression induced by TNF-α/IFN-γ and regulated the activation of ERK, IKK and...
337.

Enhancement of ATP-induced Currents by Phospholipase D1 Overexpressed in PC12 Cells

JinBongPark, YoungRaeKim, ByeongHwaJeon, Seung-KielPark, Sae-OckOh, YoungGeunKim, SangDoLee, KwangJinKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 6 223-229 (7 pages)

JinBongPark, YoungRaeKim, ByeongHwaJeon, Seung-KielPark, Sae-OckOh, YoungGeunKim, SangDoLee, KwangJinKim 저
...
- 3,000원
Using phospholipase D1 (PLD1)-overexpressing PC12 (PLD1-PC12) cells, the regulatory roles of PLD1 on ATP-induced currents were investigated. In control and PLD1-PC12 cells, ATP increased PLD activity in an external Ca2⁢ dependent manner. PLD activity stimulated by ATP was substantially larger in PLD1-PC12 cells than in control cells. In whole-cell voltage-clamp mode, ATP induced transient inward and outward currents. The outward currents inhibited by TEA or charybdotoxin were significantly...
338.

Roles of Gonadal Steroids on Exocrine Secretion of Isolated Perfused Rat Pancreas

HyungSeoPark, SeHoonKim, HyoungJinPark, MeeYoungLee, YoungHeeHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 5 217-221 (5 pages)

HyungSeoPark, SeHoonKim, HyoungJinPark, MeeYoungLee, YoungHeeHan 저
...
- 1,500원
To clarify the roles of gonadal steroids on pancreatic exocrine secretion, effects of progesterone and estradiol-17β on spontaneous and secretagogue-induced exocrine response of isolated perfused rat pancreas were investigated. Intra-arterial infusion of progesterone resulted in significant increase of the spontaneous pancreatic fluid and amylase secretion dose-dependently. However, estradiol-17β did not exert any influence on spontaneous pancreatic exocrine secretion. Exogenous secretin,...
339.

Fuctional Relationship between Rate of Fatty Acid Oxidation and Carnitine Palmitoyl Transferase I Activity in Various Rat Tissues

Yu-LeeCho, Kyung-OhDo, Tae-DongKwon, Eung-ChanJang, Keun-MiLee, Suck-KangLee, Jong-YeonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 3 207-210 (4 pages)

Yu-LeeCho, Kyung-OhDo, Tae-DongKwon, Eung-ChanJang, Keun-MiLee, Suck-KangLee, Jong-YeonKim 저
...
- 1,500원
Lipids play many structural and metabolic roles, and dietary fat has great impact on metabolism and health. Fatty acid oxidation rate is dependent on tissue types. However there has been no report on the relationship between the rate of fatty acid oxidation and carnitine transport system in outer mitochondrial membrane of many tissues. In this study, the rate of fatty acid oxidation and carnitine palmitoyltransferase(CPT) I activity in the carnitine transport system were measured to understand...
340.

PDTC Inhibits TNF-α-Induced Apoptosis in MC3T3E1 Cells

Han-JungChae, JeehyeonBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 2 199-205 (7 pages)

Han-JungChae, JeehyeonBae 저
...
- 3,000원
Osteoblasts are affected by TNF-α overproduction by immune cells during inflammation. It has been suggested that functional NF-κB sites are involved in TNF-α-induced bone resorption. Thus, we explored the effect of pyrrolidine dithiocarbamate (PDTC), which potently blocks the activation of nuclear factor (NF-κB), on the induction of TNF-α-induced activation of JNK/SAPK, AP-1, cytochrome c, caspase and apoptosis in MC3T3E1 osteoblasts. Pretreatment of the cells with PDTC blocked...

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