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Role of Na+Ca2+ Exchange in the Control of Contractility in Rabbit Basilar Arterial Smooth Muscle
Kim Eui-Yong, Han Jin 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 6 159-168 (10 pages)
The contraction of rabbit basilar artery was examined as a function of changes in the Na+ electrochemical gradient in order to determine the contribution of Na+/Ca2+ exchange to the modulation of contractility. Ouabain (10-5 M) or K+-free Tyrode solution caused an increase in tonic tension even in the presence of a Ca2+ channel blocker (10-6 M verapamil) and an α-receptor blocker (10-5 M phentolamine). After treatment with ouabain (10-5 M), contractions were augmented by reduction of external... -
Discharge Patterns and Peripheral Nerve Inputs to Cardiovascular Neurons in the Medulla of Cats: Comparison between the lateral and medial medulla
Kim, Sang-Jeong, Lim, Won-Il, Park, Myoung-Kyu, Lee, Jin, Kim, Jun 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 3 133-142 (10 pages)
45 ms after the systolic peak of arterial blood pressure. Thirteen cells could be activated antidromically by stimulation of the the T2 intermediolateral nucleus. Forty-three raphe neurons were identified as cardiovascular neurons whose mean discharge rate during one cardiac cycle was 1.02±0.12. None of these cells could be activated antidromically. Study of the interval time histogram of RVLM neurons revealed that the time to the first peak was 128±20.0 ms, being shorter than the period of a... -
The Excitatory Mechanism of Substance P in the Antral Circular Muscle of Guinea Pig Stomach
Jun, Jae-Yeoul, Kim, Sung-Joon, Choi, Youn-Baik, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 1호 5 51-60 (10 pages)
This study was carried out to elucidate the excitatory mechanisms of Substance P in the antral circular muscle, using isometric contraction recording, conventional microelectrode method and whole-cell patch clamp technique. Substance P produced tonic and phasic contractions in a dose-dependent manner and depolarized membrane potential with increased amplitude of slow waves in muscle strips. Voltage-dependent Ca2+ currents were increased by the application of Substance P from a holding potential... -
Regulatory Action of ß-adrenergic Agonist and 8-bromocyclic AMP on Calcium Currents in the Unfertilized Mouse Eggs
Haan, Jae-Hee, Cheong, Seung-Jin, Kim, Yang-Mi, Park, Choon-Ok, Hong, Seong-Geun 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 2호 6 175-184 (10 pages)
a holding potential of -80 mV, were recorded. The current-voltage (I-V) relation of calcium currents was shown to be bell-shaped; the current began to activate at -50 mV and reached its maximum (-1.33±0.16 nA: mean±S.E., n=7) at -10 mV, then decayed at around 50 mV. Calcium currents were fully activated within 7 ms ~ 20 ms and completely inactivated 200 ms after onset of the step pulse. ISP within the concentration ranges of 10-8 M ~ 10-4 M dose-dependently increased the amplitude calcium... -
Voltage-Dependent Ionic Currents and Their Regulation by GTP and Phorbol Ester in the Unfertilized Eggs of Mouse and Hamster
Kim, Ik-Hyun, Kim, Yang-Mi, Haan, Jae-Hee, Park, Choon-Ok, Hong, Seong-Geun 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 9 93-106 (14 pages)
to Ca2+ current (ica)). The current voltage relations of these currents in hamster egg were analogous to those in mouse eggs. The amplitude of ica in the hamster egg was larger than that in the mouse egg (-3.12±1.07 nA vs. -1.71±0.71 nA, mean± SD). These results suggest that the Ca2+ channels in both kinds of eggs have similar channel properties but their density, and/or conduct ance per unit area is higher in hamster eggs than in mouse eggs. Outward currents in eggs of both mouse and hamster... -
Effects of pH, PCO2, and Adenosine on the Contractility of Pig Coronary Artery
Chang, Seok-Jong, Kim, Il-Seon, Jeon, Byeong-Hwa, Kim, Se-Hoon 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 1호 5 45-54 (10 pages)
Effects of pH, PCO2, and adenosine on the vascular contractility were investigated in the pig coronary arteries. The helical strips of isolated coronary arteries were immersed in the HEPES or HCO3-/CO2-buffered Tyrode s solution equilibrated with 100% O2 or 95% O2-5% CO2 at 35℃. The contraction was recorded isometrically using a force transducer. The amplitudes of contraction induced by ACh, high K+, and electrical Held stimulation (EFS) were decreased by elevating extracellular pH (pHo) and... -
Voltage-Dependent Inactivation of Calcium Currents in the Mouse Eggs
Park, Young-Geun, Yang, Young-Seon, Yum, Myung-Kul, Hong, Seong-Geun 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 2호 3 125-132 (8 pages)
eggs of mouse were studied by using the whole cell voltage clamp technique and single microelectrode voltage clamp technique. Membrane potential was held at -80 mV and step depolarization was applied from -50 mV to 50 mV for 200 ~ 500 ms. Peak of inward Ca currents was -2 ~ -4 nA at a membrane Potentials from -20 mV to 0 mV and outward currents were not observed within the membrane voltage range studied (-50 ~ 50 mV). Inward currents were fully inactivated within 200 ms after the onset of step... -
Central Projections of Sensory Information Produced by Topical Application of Capsaicin to the Tongue in the Cat
Hong, Seung-Kil, Nahm, Sook-Hyun, Han, Hee-Chul, Suh, Young-Suk, Won, Ran, Lee, Bae-Hwan 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 1호 9 87-100 (14 pages)
In order to elucidate whether capsaicin applied topically acts as a pain-producing subastance or as a tastant, neuronal activities of the chorda tympani nerve(CN), lingual nerve(LN), solitary tract nucleus(STN), and trigeminal nucleus(TGN) were recorded while thermal and taste stimuli, and capsaicin were being applied topically, and algesics intra-arterially to the tongue of cats anesthetized with α-chloralsoe. In addition, the STN neurons were examined after wheat germ agglutinin-horseradish... -
Calcium Balance in the Heart -Annual Review Lecture, October 13, 1990-
Noble, Denis 대한생리학회 대한생리학회지 16 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 1호 1 1-16 (16 pages)


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