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카드뮴중독(中毒) 가토(家兎)의 동정맥(動靜脈)에 관하여
홍기환(Ki Hwan Hong) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 제 15권 제 1,2호 5 29-38 (10 pages)
Cd 중독(中毒)으로 가토(家兎)에 고혈압(高血壓)을 일으키고 이를 중독(中毒) 가토(家兎)와 대조(對照) 비중독(非中毒) 가토(家兎)의 간문맥(肝門脈), 흉부(胸部) 대정맥(大動脈) 및 폐정맥(肺動脈)을 적출하여 in vitro에서 장력(張力)-길이의 관계를 관찰하고 NE, K+-depolariration 및 angiotensin의 수축(收縮) 효과(效果)를 비교(比較)하였다. 1. 비중독(非中毒) 대조군의 평균 동맥압은 87.0 ± 4.7mmHg이었고 Cd 중독군(中毒群)에서는 109.0 ± 2.8mmHg로 Cd 중독(中毒)에 의하여 의의(意義)있는 증가(增加)를 나타내었다. 2.... -
고장수액의 위내 주입으로 인한 취외분비의 변동
조태순(T.S. Cho), 김원준(W.J. Kim), 홍사석(S.S. Hong) 대한약리학회 대한약리학잡지 5 Pages
대한약리학회 대한약리학잡지 1977, 제 13권 제 1호 5 29-33 (5 pages)
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Endothelium-dependent Contraction of Aorta in One-kidney, One-clip Goldblatt Hypertensive Rat
Jeon, Byeong-Hwa, Lee, Kug-Hee, Kim, Hoe-Suk, Kim, Se-Hoon, Chang, Seok-Jong 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 2호 9 269-278 (10 pages)
The mechanism of impaired endothelium-dependent relaxation in the aorta of one-kidney, one clip Goldblatt hypertensive (1K,1C-GBH) rats was investigated. 8 week-old Wistar-Kyoto (WKY) rats were made hypertensive by left renal artery stenosis with contralateral nephrectomy. Endothelium-dependent relaxation was significantly reduced in 1K,1C-GBH rats as compared with WKY rats. However, the relaxation by sodium nitroprusside in 1K,1C-GBH rats was not reduced as compared with WKY rats. The... -
Effects of Systemic and Focal Hypoxia on the Activities of Rostral Ventrolateral Medullary Neurons in Cats
Yan, Hai-Dun, Kim, Charn, Kim, Ji-Mok, Lim, Won-Il, Kim, Sang-Jeong, Kim, Jun 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 11 105-116 (12 pages)
of normal cardiopulmonary activity, during the cerebral ischemic reflex some cardiac related cells should be excited and respiration related cells inhibited. In this context, the responses of RVLM neurons to systemie and focal hypoxia were analyzed in the present study. Twenty-five adult cats of either sex were anesthetized with α-chloralose and the single neuronal activities were identified from RVLM area. For the induction of focal hypoxia in the recording site, sodium cyanide was applied... -
Effects of Anticonvulsants on Acute and Tonic Pains in the Rat
Shin, Hong-Kee 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 10 97-104 (8 pages)
Different neural substrates have been reported to be implicated in analgesic mechanisms in the acute phasic and the sustained tonic pains. To explore the differential antinociceptive action of diphenylhydantoin (DPH) and carbamazepine (CBZ) on the acute phasic and the tonic pains, changes in tail flick latency, hot plate latency and the formalin-induced nociceptive score were assessed prior to and after intraperitoneal administration of DPH (20 & 40 mg/Kg) and CBZ (20 mg/Kg). In 11 rats, CBZ was... -
Effects of Platelet-Activating Factor on Tumor Necrosis Factor-α Production by Muramyl Dipeptide- or Silica-Stimulated Alveolar Macrophages
Lee, Ji-Hee, Hah, Jong-Sik 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 8 77-84 (8 pages)
10-16 M) alone was added to AM culture, (TNF-α) production was not significantly increased above the resting level. In contrast, the combined addition of PAF (10-6 M) and muramyl dipeptide(MDP) (1.0 μg\ml) to AM cultures markedly enhanced (TNF-α) production with 8.2 fold increase compared with AM culture in resting state. This potentiative effect was 313% above the sum of the separate effects of PAF and MDP. To characterize MDP effects on (TNF-α) production, the dose-response of AM cultured... -
Enhanced Vasorelaxation Response to Cromakalim in Spontaneously Hypertensive Rats
Kim, Se-Hoon, Oh, Yeong-Seon, Kim, Hoe-Suk, Jeon, Byeong-Hwa, Chang, Seok-Jong 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 2 11-20 (10 pages)
relaxant response to cromakalim was decreased by raising the K+ concentration. 3. SHR aorta exhibited myogenic tone in resting state which was inhibited by cromakalim, verapamil or Ca2+-free PSS. Whereas, WKY aorta did not exhibit any myogenic tone in resting state. 4. When aortic rings from both strains were contracted by 20 mM K+ or NE, relaxant responses to low concentration of cromakalim (below 10-7 M) were not different between WKY and SHR, but maximum relaxant response to cromakalim (above... -
Effects of Adenosine on the Ionic Channel Activated by Metabolic Inhibition in Rabbit Ventricular Myocytes
Han, Jin, Kim, Eui-Yong, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 1 1-10 (10 pages)
The objective of the present study was to characterize the role of adenosine in regulation of ATP-sensitive K+ channel (KATP channel) activity in isolated rabbit ventricular myocytes using the patch clamp technique. Internal adenosine had little effects on KaTr channel activity. In an outside-out patch with intrapipette GTP and ATP, external adenosine stimulated KATP channel activity. In an inside-out Patch with intrapipette adenosine, ATP reduced KATP channel activity, and GTP stimulated KATP... -
Effects of Morphine on Somatosyrnpathetic Reflex and Arterial Blood Pressure Response Evoked by Stimulation of Peripheral Nerves
Huh, Min-Gang, Yan, Hai-Dun, Lim, Won-Il, Kim, Jun 대한생리학회 대한생리학회지 13 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 13 309-321 (13 pages)
In the present study, the relationship between the somatosympathetic reflexes and arterial blood pressure responses to electrical stimulation of the peripheral nerve was investigated in cats anesthetized with α-chloralose. Single sympathetic postganglionic fiber activities were recorded from the hindlimb muscle and skin nerves and also from the cervical and abdominal sympathetic chains. Effects of the morphine on responses of the sympathetic nerve and arterial blood pressure to activation of... -
Effect of Blood Pressure on Contractility of Vascular Smooth Muscle and Endothelium-Dependent Relaxation
Suh, Suk-Hyo, Park, Yee-Tae, Lee, Dong-Chul, Seo, Pil-Won, Kim, Ki-Whan 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 10 279-290 (12 pages)
This study was designed 1) to develop a hypertensive animal model in which the blood pressures (BPs) of symmetric regions (right and left upper extremities) are significantly different and 2) to test the effect of BP per se on the contractility and endothelium-dependent relaxation of vascular smooth muscle. Rabbits were anesthetized with sodium pentobarbital and ventilated with room air via animal respirator. The transverse aorta was exposed through the left second intercostal space and the...


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