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Interaction between Renin-Angiotensin and Endothelium-Derived Nitric Oxide Systems in Two-Kidney, One Clip Hypertensive Rats
Ahn, Hyun-Tack, Nah, Kook-Joo, Lee, Jong-Un 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 4 33-42 (10 pages)
and in vitro release, the latter was more rapidly decreased than the former in the contralateral kidney. The renin mRNA levels in the contralateral kidney were almost at their nadir at days 7 and 14 in 2K1C rats. It is suggested that NO does not affect the development of 2K1C hypertension in which the renin-angiotensin system has been activated. The data also confirm that RRC and renin gene expression are increased in the clipped kidney and suppressed in the contralateral kidney in 2K1C rats. -
Inositol 1,4,5-Trisphosphate-induced Increase in Ca2+-ATPase Activity in the Microsomes of Tracheal Epithelial Cells
Cho, Hyoung-Jin, Park, Sung-Shin, Kim, Young-Kee 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 9 269-278 (10 pages)
Membrane vesicles were prepared by differential centrifugation from epithelial cells of porcine trachea. Total activity of microsomal ATPases was measured spectrophotometrically by a coupled enzyme assay. The steady-state activity of the enzyme was 329±10 nmol/min mg protein. Thapsigargin, a specific antagonist of intracellular Ca2+-ATPase, inhibited about 50% of the activity, leaving 178±18 nmol/min .mg protein (n=6), indicating that the Ca2+-ATPase is one of the major microsomal ATPases.... -
Platelet-Activating Factor Potentiates the Activity of Respiratory Burst and Interleukin-1 in Rat Alveolar Macrophages
Lee, Ji-Hee 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 7 251-258 (8 pages)
The objective of the present study was to test the effect of platelet-activating factor (PAF) on rat alveolar macrophages. PAF alone did not stimulate superoxide secretion from alveolar macrophages. However, PAF (10-5 M) significantly enhanced phagocytic activator zymosan-induced superoxide secretion from alveolar macrophages. This enhancement of PAF plus zymosan was 30% above the sum of the separate effects of PAF and zymosan. Similarly, PAF 1.3 X (10-5 M) was not a direct stimulant of alveolar... -
Interaction between Cholecystokinin and Secretin in Isolated Rat Pancreatic Acini
Yoon, Shin-Hee, Hahn, Sang-June, Sim, Sang-Soo, Rhie, Duck-Joo, Song, In-Young, Baek, Hye-Jung, Kim, Myung-Suk, Jo, Yang-Hyeok 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 6 243-250 (8 pages)
possible potentiation between cholecystokinin (CCK) and secretin in amylase secretion from isolated rat pancreatic acini was investigated. Combined treatment of acini with secretin and CCK at low concentrations, which are known to be physiological, resulted in enzyme secretion larger than the arithmetic sum of their separate effects. Such a potentiating effect also occurred between secretin and A23187 (Ca ionophore), between forskolin (adenylate cyclase activator) and CCK, and between forskolin... -
Role of Endogenous Nitric Oxide in the Control of Renin Release
Lee, Je-Jung, Kim, Dong-Ho, Kim, Young-Jae, Kim, Won-Jae, Yoo, Kwang-Jay, Choi, Ki-Chul, Lee, Jong-Eun, 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 13 225-232 (8 pages)
The present study was undertaken to investigate the role of endogenous nitric oxide in renin release under different physiological conditions. In the first series of experiments, renin release was either inhibited by acute volume-expansion (VE) or stimulated by clipping one renal artery in the rat. VE was induced by intravenous infusion of saline (0.9% NaCl) up to 5% of the body weight over 45 min under thiopental (50 mg/kg, IP) anesthesia. VE caused a decrease of plasma renin concentration... -
Effects of Centrally Administered Angiotensin ll Receptor Antagonists on the Cardiovascular and Hormonal Responses to Hemorrhage in Conscious SHR
Seo, Il-Sook, Yang, Eun-Kyoung, Park, Jae-Sik, Kim, Hyeong-Jin, Lee, Won-Jung 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 2호 10 217-226 (10 pages)
The role of endogenous brain angiotensin ll (Ang ll) in mediating the cardiovascular and vasopressin responses to hemorrhage was assessed in conscious spontaneously hypertensive rats (SHR), and normotensive Wistar-Kyoto (WKY) rats. Artificial cerebrospinal fluid (aCSF) with or without losartan (DuP 753), a specific Ang ll receptor subtype I (AT1) antagonist and saralasin, a combined AT1/AT2 antagonist was administered into the cerebral lateral ventricle. Hemorrhage was performed at a rate of 3... -
Ionic Dependence and Modulatory Factors of the Background Current Activated by Isoprenaline in Rabbit Ventricular Cells
Leem, Chae-Hun, Lee, Suk-Ho, So, In-Suk, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 1호 2 15-26 (12 pages)
In order to elucidate the properties of the background current whole cell patch clamp studies were performed in rabbit ventricular cells. Ramp pulses of ±80 mV from holding potential of 40 mV(or 20 mV) at the speed of 0.8 V/sec were given every 30 sec(or 10 sec) and current-voltage diagrams(I-V curve) were obtained. For the activation of the background current isoprenaline, adenosine 3 ,5 -cyclic monophosphate(dBcAMP), guanosine 3 ,5 -cyclic monophosphate(cGMP), and N6-2 -o-dibutyryladenosine 3... -
Effect of pH on Calcium-Activated Potassium Channels in Pulmonary Arterial Smooth Muscle Cells of the Rabbit
Lee, Suk-Ho, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 1호 2 17-26 (10 pages)
Single smooth muscle cells of the rabbit pulmonary artery were isolated by treatment with collagenase and elastase. Using the patch clamp technique, potassium channel activity was recorded from the inside-out membrane patch. The channel had a sin히e channel conductance of about 360 pS in symmetrical concentration of K on both sides of the patch, 150 mM, and had a linear current-voltage relationship. During the application of 10 mM tetraethylammonium (TEA) to the intracellular membrane surface,... -
내측 편도핵의 위산분비 촉진작용에서 미주신경의 역할
김명석(Kim, Myung-Suk), 조양혁(Jo, Yang-Hyeok), 윤신희(Yoon, Shin-Hee), 한상준(Hahn, Sang-June), 이덕주(Rhie, Duck-Joo), 김정진(Kim, Chung-Chin) 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1989, 제 23권 제 2호 14 393-400 (8 pages)
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가토 신피질 Brush Border Membrane과 Basolateral Membrane Vesicle에서 유기이온의 이동에 대한 동력학적 분석
김용근(Kim, Yong-Keun), 우재석(Woo, Jae-Suk), 이상호(Lee, Sang-Ho) 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1987, 제 21권 제 2호 10 273-282 (10 pages)
가토 신피질에서 분리한 brush border membrane (BBM)과 basolateral membrane vesicle (BLM)에서 유기 음이온인 p-aminohippuric acid (PAH)와 유기 양이온인 tetraethylammonium (TEA)의 이동에 대한 동력학적 분석을 하였다. BLM에서 PAH에 대한 Km과 Vmax값은 각각 0.34±0.02 mM과 0.22±0.07 nmol/mg protein/20s였으며 BBM에서 각 값은 8.46±0.57 mM과 4.43±0.40 nmol/mg protein/20s였다. BLM에서 용액내 Na의 제거는 PAH에 대한 Km 값에는 영향없이 Vmax 값을 변화시켰다. BBM에서 TEA이동에 대한 Km과 Vmax 값은 각각...


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