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381.

Effects ofSphingosine-1-phosphate, Furosemide and Indomethacin on Mucin Release from Airway Goblet Cells

Ju-OckKim, HyungSooKim, Sun-YoungKim, Seong-SooJeong, HoJinHeo, JeongHoSeok, ChoongJaeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 4 155-158 (4 pages)

Ju-OckKim, HyungSooKim, Sun-YoungKim, Seong-SooJeong, HoJinHeo, JeongHoSeok, ChoongJaeLee 저
...
- 1,500원
In this study, we investigated whether sphingosine-1-phosphate, furosemide, and indomethacin affect mucin release from airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled and chased for 30 min or 24 hr in the presence of varying concentrations of the above agents to assess the effects on 3H-mucin release. Sphingosine-1-phosphate stimulated mucin release during 30 min of treatment period in a dose-dependent manner. However, furosemide...
382.

Insulin Resistance of Skeletal Muscle was Recovered by Leptin Injection in vivo, but not in vitro, in High-fat Diet Fed Rats

Kyung-OhDoh, Jeong-OakPark, Jeong-RyaeJeon, Jong-YeonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 8 125-130 (6 pages)

Kyung-OhDoh, Jeong-OakPark, Jeong-RyaeJeon, Jong-YeonKim 저
...
- 3,000원
We examined the effect of leptin on the insulin resistance in skeletal muscles by measuring the glucose transport. Male Wistar rats were fed with chow or high-fat diets for 30 days. Three days before sacrifice, high-fat fed rats were subcutaneously injected with leptin (1 mg/kg body weight) for 3 days. The glucose transports in the epitrochlearis and soleus muscle were not different among the experimental groups under basal state, however these were decreased significantly in the high fat-diet...
383.

Regulation of L-type Calcium Channel Current by Somatostatin in Guinea-Pig Gastric Myocytes

YoungChulKim, JaeHoonSim, SangJinLee, TongMookKang, SungJoonKim, SeungRyulKim, SeiJinYoun, SangJeonLee, Wen-XieXu6, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 5 103-108 (6 pages)

YoungChulKim, JaeHoonSim, SangJinLee, TongMookKang, SungJoonKim, SeungRyulKim, SeiJinYoun, SangJeonLee, Wen-XieXu6, InsukSo, KiWhanKim 저
...
- 3,000원
To study the direct effect of somatostatin (SS) on calcium channel current (IBa) in guinea-pig gastric myocytes, IBa was recorded by using whole-cell patch clamp technique in single smooth muscle cells. Nicardipine (1μM), a L-type Ca2+ channel blocker, inhibited IBa by 98⁑1.9% (n=5), however IBa was decreased in a reversible manner by application of SS. The peak IBa at 0 mV were decreased to 95⁑1.1, 92⁑1.9, 82⁑4.0, 66⁑5.8, 10⁑2.9% at 10⁣10, 10⁣9,...
384.

Ca2+-induced Ca2+ Release from Sarcoplasmic Reticulum Negatively Regulates Myocytic ANP Release in Beating Rabbit Atria

DanLi, HeXiuQuan, JinFuWen, JingYuJin, SungHunPark, SunYoungKim, SungZooKim, KyungWooCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 3 87-94 (8 pages)

DanLi, HeXiuQuan, JinFuWen, JingYuJin, SungHunPark, SunYoungKim, SungZooKim, KyungWooCho 저
...
- 3,000원
It is not clear whether Ca2⁢-induced Ca2⁢ release from the sarcoplasmic reticulum (SR) is involved in the regulation of atrial natriuretic peptide (ANP) release. Previously, we have shown that nifedipine increased ANP release, indicating that Ca2⁢ entry via voltage-gated L-type Ca2⁢ channel activation decreases ANP release. The purpose of the present study was two-fold: to define the role of SR Ca2⁢ release in the regulation of ANP release and whether Ca2⁢...
385.

D-Amphetamine Causes Dual Actions on Catecholamine Release from the Rat Adrenal Medulla

Geon-HanLim, Gwang-MoonNa, Seon-YoungMin, Yoo-SeokSeo, Chan-WonPark, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 7 45-54 (10 pages)

Geon-HanLim, Gwang-MoonNa, Seon-YoungMin, Yoo-SeokSeo, Chan-WonPark, Dong-YoonLim 저
...
- 3,000원
of the dihydropyridine L-type Ca2⁢ channels, and cyclopiazonic acid, an inhibitor of cytoplasmic Ca2⁢ ATPase only for the first period (4 min). However, in the presence of high concentration (500μM), d-amphetamine rather inhibited the CA secretory responses evoked by the above all of secretagogues. Collectively, these experimental results suggest that d-amphetamine at low concentrations enhances the CA secretion from the rat adrenal medulla evoked by cholinergic stimulation (both...
386.

Ca2+-activated K+ Currents of Pancreatic Duct Cells in Guinea-pig

Han-WookLee, JingchaoLi, Na-YounKoo, ZhengGenPiao, SungMinHwang, Jae-WoongHan, Han-SaemChoi, Jong-HeunLee, JoongSooKim, KyungpyoPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 7 335-338 (4 pages)

Han-WookLee, JingchaoLi, Na-YounKoo, ZhengGenPiao, SungMinHwang, Jae-WoongHan, Han-SaemChoi, Jong-HeunLee, JoongSooKim, KyungpyoPark 저
...
- 1,500원
were inhibited by 40.4⁑% (n=3), 87.0⁑% (n=5) and 82.5⁑% (n=9) by 1 mM Ba2⁢, 5 mM TEA and 100 nM iberiotoxin, respectively. Particularly, an almost complete inhibition of the current by 100 nM iberiotoxin further confirmed that this current was activated by intracellular Ca2⁢. The K⁢ current may play a role in secretory process, since recycling of K⁢ is critical for the initiation and sustaining of Cl⁣ or HCO3⁣ secretion in these cells.
387.

Effects of Proinflammatory Cytokines and Natural Products on Mucin Release from Cultured Hamster Tracheal Surface Epithelial Cells

JiSunPark, HyoungSooKim, JeongHoSeok, GangMinHur, JongSunPark, UnKyoSeo, ChoongJaeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 6 329-334 (6 pages)

JiSunPark, HyoungSooKim, JeongHoSeok, GangMinHur, JongSunPark, UnKyoSeo, ChoongJaeLee 저
...
- 3,000원
In this study, we investigated whether TNF-alpha, IL-1beta, CTMA (carboxymethyl trimethylammonium) and LPD (Lup-20[29]-ene-3beta,28-diol) affect mucin release from airway goblet cells and compared the activities of these agents with the inhibitory action of PLL and the stimulatory action of ATP on mucin release. Confluent primary hamster tracheal surface epithelial (HTSE) cells were metabolically radiolabeled with 3H-glucosamine for 24 h and chased for 30 min in the presence of varying...
388.

Effect of Defibrotide on Rat Reflux Esophagitis

HyoungKiKim, SooRanChoi, SangJinChoi, MyungSupChio, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 5 319-328 (10 pages)

HyoungKiKim, SooRanChoi, SangJinChoi, MyungSupChio, YongKyooShin 저
...
- 3,000원
gastric secretion, lipid peroxidation, polymorphonuclear leukocytes (PMNs) accumulation, polymorphonuclear leukocytes adherence, superoxide anion and hydrogen peroxide production in PMNs, scavenge of hydroxyl radical and hydrogen peroxide, cytokine (interleukin-1β, tumor necrosis factor-α) production in blood, and intracellular calcium mobilization in PMNs. Defibrotide did not inhibit the gastric secretion and not change the gastric pH. Treatment of esophagitis rats with defibrotide inhibited...
389.

Influence of Cilnidipine on Catecholamine Release in the Perfused Rat Adrenal Medulla

Seong-ChangWoo, Young-JooBaek, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.5 5 265-272 (8 pages)

Seong-ChangWoo, Young-JooBaek, Dong-YoonLim 저
...
- 3,000원
L-type Ca2⁢ channels and cyclopiazonic acid (10μM), an inhibitor of cytoplasmic Ca2⁢-ATPase were also inhibited. Moreover, ω-conotoxin GVIA (1μM), a selective blocker of the N-type Ca2⁢ channels, given into the adrenal gland for 60 min, also inhibited time-dependently CA secretory responses evoked by Ach, high K⁢, DMPP, McN-A-343, Bay-K-8644 and cyclopiazonic acid. Taken together, these results demostrate that cilnidipine inhibits CA secretion evoked by stimulation of...
390.

Double-stranded RNA Induces Inflammatory Gene Expression in Schwann Cells: Implication in the Wallerian Degeneration

HyunkyoungLee, ChanheePark, Se-YoungChoi, SeogBaeOh, KyungpyoPark, Joong-SooKim, SungJoongLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.5 3 253-258 (6 pages)

HyunkyoungLee, ChanheePark, Se-YoungChoi, SeogBaeOh, KyungpyoPark, Joong-SooKim, SungJoongLee 저
...
- 3,000원
The transcripts of TLR2, 3, 4, and 9 were detected on the primary Schwann cells as well as on iSC. The stimulation of iSC with poly (I：C), a synthetic ligand for the TLR3, induced the expression of TNF-α and RANTES. In addition, poly (I：C) stimulation induced the iNOS expression and nitric oxide secretion in iSC. These results suggest that the TLRs may be involved in the inflammatory activation of Schwann cells, which is observed during Wallerian degeneration after a peripheral nerve injury.

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