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초등학교 과학 교과서의 편집 디자인에 대한 시선 이동 분석
양일호, 김성운 한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 16 Pages
한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 2015, 제 5권 제 3호 3 19-34 (16 pages)
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구순구개열 환자에서 급속 구개 확장술에 대한 고찰
김민진, 안장훈, 조영석, 안소미, 김주원 대한구순구개열학회 대한구순구개열학회지 9 Pages
대한구순구개열학회 대한구순구개열학회지 2014, 제 17권 1호 6 45-53 (9 pages)
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Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth
Dong Ho Bak, Mi Ji Choi, Soon Re Kim, Byung Chul Lee, Jae Min Kim, Eun Su Jeon, Wonil Oh, Ee Seok Lim, Byung Cheol Park, Moo Joong Kim, Ju 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 9 555-566 (12 pages)
Human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) are used in tissue repair and regeneration; however, the mechanisms involved are not well understood. We investigated the hair growth-promoting effects of hUCB-MSCs treatment to determine whether hUCB-MSCs enhance the promotion of hair growth. Furthermore, we attempted to identify the factors responsible for hair growth. The effects of hUCB-MSCs on hair growth were investigated in vivo, and hUCB-MSCs advanced anagen onset and hair... -
Functional identification of protein phosphatase 1-binding consensus residues in NBCe1-B
KyuPilLee, HyunJinKim, DongkiYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 10 91-99 (9 pages)
Protein phosphatase 1 (PP1) is involved in various signal transduction mechanisms as an extensive regulator. The PP1 catalytic subunit (PP1c) recognizes and binds to PP1-binding consensus residues (FxxR/KxR/K) in NBCe1-B. Consequently, we focused on identifying the function of the PP1-binding consensus residue, 922FMDRLK927, in NBCe1-B. Using site-directed mutagenesis and co-immunoprecipitation assays, we revealed that in cases where the residues were substituted (F922A, R925A, and K927A) or... -
Ardipusilloside-I stimulates gastrointestinal motility and phosphorylation of smooth muscle myosin by myosin light chain kinase
ZhiliXu, HanyeLiang, MingboZhang, XiaojunTao, DeqiangDou, LipingHu, TingguoKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 5 609-616 (8 pages)
Ardipusilloside-I is a natural triterpenoid saponin, which was isolated from Ardisia pusilla A. DC. The aim of the study was to evaluate the stimulation of ardipusilloside-I on gastrointestinal motility in vitro and in vivo. The experiment of smooth muscle contraction directly monitored the contractions of the isolated jejunal segment (IJS) in different contractile states, and the effects of ardipusilloside-I on myosin were measured in the presence of Ca2+-calmodulin using the activities of 20... -
Seasonal acclimation in sudomotor function evaluated by QSART in healthy humans
YoungOhShin, Jeong-BeomLee, Jeong-HoKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.5 7 499-505 (7 pages)
The quantitative sudomotor axon reflex testing (QSART) is a classic test of routine postganglionic sudomotor function. We investigated sudomotor function by QSART after summer (July 2012) and winter (January 2013) seasonal acclimation (SA) in the Republic of Korea. QSART with acetylcholine (ACh) iontophoresis were performed to determine directly activated (DIR) and axon reflex-mediated (AXR1, 2) sweating rate. Onset time of axon reflex, activated sweat gland density (ASGD), activated sweat gland... -
Seasonal Acclimatization in Summer versus Winter to Changes in the Sweating Response during Passive Heating in Korean Young Adult Men
Jeong-BeomLee, Tae-WookKim, Young-KiMin, Hun-MoYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 2 9-14 (6 pages)
We investigated the sweating response during passive heating (partial submersion up to the umbilical line in 42±0.5oC water, 30 min) after summer and winter seasonal acclimatization (SA). Testing was performed in July during the summer, 2011 [summer-SA; temp, 25.6±1.8oC; relative humidity (RH), 82.1±8.2%] and in January during the winter, 2012 (winter-SA; temp, −2.7±2.9oC; RH, 65.0±13.1%) in Cheonan (126o52'N, 33.38'E), Republic of Korea. All experiments were carried out in an... -
Effect of Vestibulosympathetic Reflex and Baroreflex on Expression of pERK in the Nucleus Tractus Solitarius following Acute Hypotension in Conscious Rats
XianJiang, YanLan, Yuan-ZheJin, JooYoungPark, ByungGeonPark, AbdulNasirAmeer, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.4 11 353-358 (6 pages)
Control of blood pressure is maintained by the interaction between the arterial baroreflex and vestibulosympathetic reflex during postural changes. In this study, the contributions of vestibular receptors and baroreceptors to the maintenance of blood pressure following acute hypotension were compared in terms of phosphorylated extracellular regulated protein kinase (pERK) expression in the nucleus tractus solitaries (NTS). Expression of pERK in the NTS was measured in conscious rats that had... -
Characteristics of Diprophylline-Induced Bidirectional Modulation on Rat Jejunal Contractility
Fang-FeiLiu, Da-PengChen, Yong-JianXiong, Bo-ChaoLv, YuanLin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.1 6 47-53 (7 pages)
In this study, we propose that diprophylline exerts bidirectional modulation (BM) on the isolated rat jejunal segment depending on its contractile state. The results supported the hypothesis. Dipro-phylline (20 μM) exerted stimulatory effects on the contractility of jejunal segment in six low contractile states while inhibitory effects in six high contractile states, showing the characteristics of BM. Diprophylline-induced stimulatory effect was significantly blocked by atropine, indicating the... -
A Simple Dosing Scheme for Intravenous Busulfan Based on Retrospective Population Pharmacokinetic Analysis in Korean Patients
SangminChoe, GayeongKim, Hyeong-SeokLim, Sang-HeonCho, Jong-LyulGhim, JinAhJung, Un-JibKim, GyujeongNoh, Kyun-SeopBae, DonghoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 7 273-280 (8 pages)
9%. Based on a CL estimate from the final PK model, a simple dosage scheme to achieve the target AUC0-inf (defined as median AUC0-inf with a once-daily dosage) of 26.18 mg/lㆍhr, was proposed: 24.79ㆍABW0.5 mg q24h, where ABW represents the actual body weight in kilograms. The dosing scheme reduced the unexplained interindividual variabilities of CL and Vd of iBu with ABW being a significant covariate affecting clearance of iBU. We propose a new simple dosing scheme for iBu based only on ABW.


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