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The activation of α2-adrenergic receptor in the spinal cord lowers sepsis-induced mortality
Sung-SuKim, Soo-HyunPark, Jae-RyungLee, Jun-SubJung, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 5 495-507 (13 pages)
The effect of clonidine administered intrathecally (i.t.) on the mortality and the blood glucose level induced by sepsis was examined in mice. To produce sepsis, the mixture of D-galactosamine (GaLN; 0.6 g/10 ml)/lipopolysaccharide (LPS; 27 µg/27 µl) was treated intraperitoneally (i.p.). The i.t. pretreatment with clonidine (5 µg/5 µl) increased the blood glucose level and attenuated mortality induced by sepsis in a dose-dependent manner. The i.t. post-treatment with... -
Effect of D-glucose feeding on mortality induced by sepsis
Sung-SuKim, Yun-BeomSim, , Soo-HyunPark, Jae-RyeongLee, NaveenSharma, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 11 83-89 (7 pages)
Sepsis is the life-threatening response to infection which can lead to tissue damage, organ failure, and death. In the current study, the effect of orally administered D-glucose on the mortality and the blood glucose level induced by D-Galactosamine (GaLN)/lipopolysaccharide (LPS)-induced sepsis was examined in ICR mice. After various amounts of D-glucose (from 1 to 8 g/kg) were orally fed, sepsis was induced by injecting intraperitoneally (i.p.) the mixture of GaLN /LPS. Oral pre-treatment with... -
The Safety and Pharmacokinetics of Cyanidin-3-Glucoside after 2-Week Administration of Black Bean Seed Coat Extract in Healthy Subjects
SangilJeon, SeunghoonHan, JongtaeLee, TaegonHong, Dong-SeokYim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 4 249-253 (5 pages)
We analyzed the pharmacokinetics of C3G on data from twelve subjects, after 2-week multiple dosing of black bean (Phaseolus vulgaris, Cheongjakong-3-ho) seed coat extract, using the mixed effect analysis method (NONMEM, Ver. 6.2), as well as the conventional non-compartmental method. We also examined the safety and tolerability. The PK analysis used plasma concentrations of the C3G on day 1 and 14. There was no observed accumulation of C3G after 2-week multiple dosing of black bean seed coat... -
Helicobacter pylori Vacuolating Toxin Exhibits Polar Activity of Cl- Secretion and Secretory Response to Carbachol in T84 Cells
NanGeJin, YongRiJin, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.5 8 289-293 (5 pages)
To investigate whether VacA (vacuolating toxin) produced by Helicobacter pylori `Korean stain 99 induces intestinal secretion, purified VacA was added to T84 cell monolayers mounted in Ussing chambers, and electrical parameters were monitored. Mucosal addition of low pH-pretreated VacA increased short circuit current (Isc). The effect was time- and dose-dependent and saturable. The time-to-peak Isc was concentration-dependent. Chloride channel inhibitors, niflumic acid or 5-... -
Implant stability, marginal bone change and success rate of DIO� SM submerged internal-type implants placed at the posterior missing area: A prospective single arm clinical trial
Bo-Han Li, Kang-Mi Pang, Jong-Chul Park, Soung-Min Kim, Ji-Eun Moon, Jeong-Yeon Yun, Seung-Ryong Ha, Jae-Bong Lee, Myung-Jin Kim, Jong-Ho 대한치과이식임플란트학회 Journal of Dental Implant Research 8 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2010, 제 29권 1호 10 71-78 (8 pages)
The present clinical study was undertaken to evaluate the implant stability, marginal bone change and the survival rate of DIO� SM submerged internal-type implants placed at the partially edentulous posterior missing area. In this prospective study, 72 patients treated with 111 DIO� SM submerged internal-type implants placed at the posterior maxilla or mandible after loss of single or multiple teeth were included. The ISQ (implant stability quotient) value was measured after the first and second... -
The Current Status and Future Outlook of Quantum Dot-Based Biosensors for Plant Virus Detection
한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2018, 34권 2호 1 85-92 (8 pages)
Enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR), widely used for the detection of plant viruses, are not easily performed, resulting in a demand for an innovative and more efficient diagnostic method. This paper summarizes the characteristics and research trends of biosensors focusing on the physicochemical properties of both interface elements and bioconjugates. In particular, the topological and photophysical properties of quantum dots (QDs) are discussed, along... -
LotG: A Design of Adaptive u-learning System
Yvette E. Gelogo, Hyejin Kim 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 11 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2015, 제 5권 제 3호 25 239-249 (11 pages)
The concept of ubiquitous computing and u-learning goes beyond portable computers. As new technologies evolve and more pervasive forms of technology emerge, computers will become ‘invisible’ and will be embedded in all aspects of our life. Wearable computers and embedded microchips are not as unbelievable or mind boggling. These innovations may have appeared strange and futuristic at first but, over time they blended into our everyday lives. In this age of progress and great change, we tend to... -
A Case Study on Korean Capacity-Building Programs for Climate-Change Experts
김민철, 김지환, 김현민 한국핵심역량교육학회 핵심역량교육연구 19 Pages
한국핵심역량교육학회 핵심역량교육연구 2018, 제 3권 제 1호 (통권 4권) 4 67-85 (19 pages)
The importance of climate technology cooperation has been steadily increasing since the Paris Agreement signed in December 2015. In order to address the demand of the international community and the will of the Korean government, it has become necessary to enhance the understanding about global climate technology cooperation and to build capacities of human resources in the science and technology field. Developing a competency enhancement model, planning for training programs, and building... -
파킨슨병 환자에게 Lee Silverman Voice Treatment-BIG(LSVT-BIG) 프로그램의 적용이 운동기능과 삶의 질에 미치는 효과
박강현, 김재환, 장종식 대한신경계작업치료학회 재활치료과학 12 Pages
대한신경계작업치료학회 재활치료과학 2019, 제 8권 1호 6 73-84 (12 pages)
목적: 파킨슨병 환자를 위해 개발된 표준화된 운동프로그램과 작업기반의 활동으로 구성된 Lee Silverman Voice Treatment (LSVT) BIG 치료 프로그램을 지역사회에 거주하는 파킨슨병 환자에게 제공한 후 파킨슨병 환자의 운동기능과 삶의 질에 어떠한 영향을 미치는 지를 알아보고자 하였다연구방법: 본 연구는 단일군 전후실험설계(one-group pretest and post test design)를 사용하였다. 치료 전·후에는 통합형 파킨슨병 평가척도(Unified Parkinson’s Disease Rating Scale-Ⅲ: UPDRS-Ⅲ), Time up and go(TUG), 파킨슨 질병... -
Supporting Preschool Children’s Early Writing with Self-Regulated Learning Strategies
Siew Kim Siew, Mariani Binti Md Nor 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 25 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2019, Vol.13 No.2 5 69-93 (25 pages)
Research suggests that early writing is crucial in the development of young children’s literacy skills and links to their conventional literacy outcomes in elementary school and beyond. In order to enhance the will and the skills to express thoughts explicitly and effectively in early writing among preschool children, self-regulated learning (SRL) was suggested. This experimental study involved seventy-five preschool children, aged from five to six years old in Malaysia, aimed to investigate...


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