학지사 뉴논문

총 435건 검색

본문검색 결과만 보기

정확도순

최신순

등재순

발행기간

전체
최근 1년
최근 3년
직접입력

적용하기

본문검색

포함

제외

10개씩

391.

Cisplatin-induced Alterations of Na+-dependent Phosphate Uptake in Renal Epithelial Cells

SungJuLee, ChaeHwaKwon, YongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.2 5 71-77 (7 pages)

SungJuLee, ChaeHwaKwon, YongKeunKim 저
...
- 3,000원
Cisplatin treatment increases the excretion of inorganic phosphate in vivo. However, the mechanism by which cisplatin reduces phosphate uptake through renal proximal tubular cells has not yet been elucidated. We examined the effect of cisplatin on Na⁢-dependent phosphate uptake in opossum kidney (OK) cells, an established proximal tubular cell line. Cells were exposed to cisplatin for an appropriate time period and phosphate uptake was measured using [32P]-phosphate. Changes in the number...
392.

Modulation of Large Conductance Ca2+-activated K+ Channel of Skin Fibroblast (CRL-1474) by Cyclic Nucleotides

JihyunYun, SeungtaeKim, HyoweonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 9 131-134 (4 pages)

JihyunYun, SeungtaeKim, HyoweonBang 저
...
- 1,500원
Potassium channels in human skin fibroblast have been studied as a possible site of Alzheimer disease pathogenesis. Fibroblasts in Alzheimer disease show alterations in signal transduction pathway such as changes in Ca2⁢ homeostasis and/or Ca2⁢-activated kinases, phosphatidylinositol cascade, protein kinase C activity, cAMP levels and absence of specific K⁢ channel. However, little is known so far about electrophysiological and pharmacological characteristics of...
393.

Effects of Prostaglandin F2α on Membrane Potentials and K+ Currents in Rabbit Middle Cerebral Arterial Cells

NariKim, JinHan, WonGueKim, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.4 5 301-309 (9 pages)

NariKim, JinHan, WonGueKim, EuiyongKim 저
...
- 3,000원
The purpose of our investigation was to examine the effects of prostaglandin F2α (PGF2α) on membrane potentials, Ca2⁢-activated K⁢ (KCa) channels, and delayed rectifier K⁢ (KV) channels using the patch-clamp technique in single rabbit middle cerebral arterial smooth muscle cells. PGF2α significantly hyperpolarized membrane potentials and increased outward whole-cell K⁢ currents. PGF2α increased open-state probability of KCa channels without the change of the open and...
394.

Depression of L-type Ca2+ and Transient Outward K+ Currents in Endotoxin-treated Rat Cardiac Myocytes

KyuSangPark, BooSooLee, InDeokKongJoongWooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 11 623-630 (8 pages)

KyuSangPark, BooSooLee, InDeokKongJoongWooLee 저
...
- 3,000원
Decreased cardiac contractility occurs in endotoxicosis, but little is known about the ionic mechanism responsible for myocardial dysfunction. In this study, we examined the changes in Ca2⁢ and K⁢ currents in cardiac myocytes from endotoxin-treated rat. Ventricular myocytes were isolated from normal and endotoxemic rats (ex vivo), that were treated for 10 hours with Salmonella enteritidis lipopolysaccharides (LPS; 1.5 mg/kg) intravenously. Normal cardiac myocytes were also incubated...
395.

Sensitivity of Rabbit Cerebral Artery to Serotonin is Increased with the Moderate Increase of Extracellular K+

SukHyoSuh, SungJinPark, JaiYoungChoi, JaeHoonSim, YoungChulKim, SungJoonKim, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 6 695-703 (9 pages)

SukHyoSuh, SungJinPark, JaiYoungChoi, JaeHoonSim, YoungChulKim, SungJoonKim, InsukSo, KiWhanKim 저
...
- 3,000원
[K⁢]O can be increased under a variety of conditions including subarachnoid hemorrhage. The increase of [K⁢]O in the range of 5∼15 mM may affect tensions of blood vessels and can change their sensitivity to various vasoactive substances. Therefore, it was examined in the present study whether the sensitivity of cerebral arteries to vasoactive substances can be changed with the moderate increase of [K⁢]O, using Mulvany-type myograph and [Ca2⁢]c measurement. The...
396.

Alterations in Serum BDNF and GDNF Levels after 12 Weeks of Antidepressant Treatment in Female Outpatients with Major Depressive Disorder

Young-Min Park, Bun-Hee Lee 대한신경정신의학회 Psychiatry Investigation 6 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 11 818-823 (6 pages)

Young-Min Park, Bun-Hee Lee 저
...
- 3,000원
Objective_Some clinical studies have found alterations in the levels of serum brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) after applying antidepressant treatment in patients with major depressive disorder (MDD). We evaluated the serum BDNF and GDNF levels before and after 12 weeks of antidepressant treatment in MDD outpatients. Methods_Serum BDNF and GDNF levels were measured in 23 female MDD outpatients at baseline and after 12 weeks of...
397.

양전자방출단층촬영을 이용한 초점주의와 작동기억의 뇌 활성화 양상 비교

김재진, 조상수, 김명선, 손정우, 이재성, 이동수, 이명철, 권준수 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 2001, 제 40권 제 2호 9 270-278 (9 pages)

김재진, 조상수, 김명선, 손정우, 이재성, 이동수, 이명철, 권준수 저
...
- 3,000원
연구목적： 단순 초점주의 과제와 보다 고도의 집중을 요하는 작동기억 과제를 수행하는 동안의 뇌 활성화 양상을 비 교하여, 두 인지기능 과정을 매개하는 정상적 신경회로의 특성과 차이를 알아보는 것을 목적으로 하였다. 방 법： 정상인 14명을 대상으로 시각처리 대조 과제, 단순 초점주의 과제, 작동기억 과제 등 세 가지 인지과제를 주고, 과제 수행 동안 [15O]H2O를 추적자로 한 양전자방출단층촬영을 실시한 후 감산분석을 통해 초점주의 와 작동기억의 신경회로 지도를 작성하여 비교분석하였다. 결 과： 초점주의 동안...
398.

대학생에서의 해리경험, 대처방식, 최면감수성의 관계

이정식, 이우경, 이상백, 박상준, 오홍석 대한신경정신의학회 신경정신의학 8 Pages

대한신경정신의학회 신경정신의학 2009, 제 48권 제 4호 8 247-254 (8 pages)

이정식, 이우경, 이상백, 박상준, 오홍석 저
...
- 3,000원
399.

Cu++-Catalyzed Peroxidation이 Collagen Gelation에 미치는 영향

정명희(Myung Hee Chung), 김명석(Myung Suk Kim), 이정수(Chung Soo Lee) 대한약리학회 대한약리학잡지 10 Pages

대한약리학회 대한약리학잡지 1983, 제 19권 제 2호 5 35-44 (10 pages)

정명희(Myung Hee Chung), 김명석(Myung Suk Kim), 이정수(Chung Soo Lee) 저
...
- 3,000원
있어서 metal ions이 관여함이 시사되고 있다. 이미 알려진 reactive oxygen species와 metal ions의 상호작용 이외에 특히 Cu++과 H2O2가 강력한 peroxidative action을 나타낸다는 사실이 알려져 있으며 Cu++-H2O2가 biological system 에서의 조직파괴에 관여할 가능성이 저자들에 의해서 효소 및 조직치 구조 단백질의 gradation 효과를 관찰함으로써 시사되었다. 본 연구는 H2O2 혹은 H2O2를 생성하는 효소계(xanthine과 xanthine oxidase 및 glucose과 glucose oxidase)에 Cu++을 첨가하여 Cu++-H2O2에 의한 peroxidation의 효과를...
400.

Ca2+-activated Cl- Current in Gastric Antral Myocytes

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 4 143-150 (8 pages)

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 저
...
- 3,000원
the Nernst equation. Extracellular addition of N-phenylanthranilic acid and niflumic acid which are known anion channel blockers abolished the caffeine induced current. Intracellular application of a high concentration of EGTA also abolished this current. Application of c-AMP, c-GMP, heparin, or AIF-4 made no remarkable changes to this current. Sodium replacement with the impermeable cation N-methylglucamine or with Cd2+ rarely affected this current. From the above results it is suggested that...

한주간 이슈검색어