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401.

Reoxygenation Stimulates EDRF(s) Release from Endothelial Cells of Rabbit Aorta

SukHyoSuh, JaeJinHan, SungJinPark, JaiYoungChoi, JaeHoonSim, YoungChulKim, KiWhanKim* 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 4 393-404 (12 pages)

SukHyoSuh, JaeJinHan, SungJinPark, JaiYoungChoi, JaeHoonSim, YoungChulKim, KiWhanKim* 저
...
- 4,100원
We have reported that hypoxia stimulates EDRF(s) release from endothelial cells and the release may be augmented by previous hypoxia. As a mechanism, it was hypothesized that reoxygenation can stimulate EDRF(s) release from endothelial cells and we tested the hypothesis via bioassay experiment. In the bioassay experiment, rabbit aorta with endothelium was used as EDRF donor vessel and rabbit carotid artery without endothelium as a bioassay test ring. The test ring was contracted by...
402.

The Role of Somatostatin in Nociceptive Processing of the Spinal Cord in Anesthetized Cats

SungJunJung, JooMinPark, JunHoLee, JihyeLee, SangJeongKim, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 1 365-373 (9 pages)

SungJunJung, JooMinPark, JunHoLee, JihyeLee, SangJeongKim, JunKim 저
...
- 3,000원
Somatostatin (SOM) is one of the major neuropeptides in dorsal root ganglion cells, but its role in spinal nociceptive process has not been well known. In present study we aimed to investigate the effect of SOM on the response of dorsal horn neurons to the various types of peripheral nociceptive stimuli in anesthetized cats. Using carbon-filament microelectrode, the single cell activities of wide dynamic range neurons were recorded from the lumbosacral enlargement after noxious mechanical...
403.

Characteristics of Hypoxic Pulmonary Vasoconstriction of the Rat Study by the Vessel Size and Location in the Lung

Sang-JinLeeKiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 10 321-328 (8 pages)

Sang-JinLeeKiWhanKim 저
...
- 3,000원
Pulmonary blood vessels with diameters of 200∼400 μm produce considerably more force in response to vasoconstrictor drugs than those which are either smaller or larger. We have therefore investigated whether or not hypoxic pulmonary vasoconstriction (HPV) is more powerful in vessels of these diameters. We have also looked at the possibility that vessels from different regions of the lung respond differently. To do this we have grouped vessels according to their location within the lung as...
404.

Effect of the Inhibition of Phospholipase A2 in Generation of Free Radicals in Intestinal Ischemia/Reperfusion Induced Acute Lung Injury

YoungManLee, Yoon-yubPark, TeoanKim, HyunG.Cho, YoonJeongLee, JohnE.Repine 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 4 263-273 (11 pages)

YoungManLee, Yoon-yubPark, TeoanKim, HyunG.Cho, YoonJeongLee, JohnE.Repine 저
...
- 4,000원
The role of phospholipase A2 (PLA2) in acute lung leak induced by intestinal ischemia was investigated in association with neutrophilic respiratory burst. To induce lung leak, we generated intestinal ischemia for 60 min prior to the 120 min reperfusion by clamping superior mesenteric artery in Sprague-Dawley rats. Acute lung leak was confirmed by the increased lung leak index and protein content in bronchoalveolar fluid. These changes were inhibited by mepacrine, the non-specific PLA2...
405.

Magnesium Suppresses the Responses of Dorsal Horn Cell to Noxious Stimuli in the Rat

HongKeeShin, JinHyukKim, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 1 237-244 (8 pages)

HongKeeShin, JinHyukKim, KeeSoonKim 저
...
- 3,000원
Magnesium ion is known to selectively block the N-methyl-D-aspartate (NMDA)-induced responses and to have anticonvulsive action, neuroprotective effect and antinociceptive action in the behavioral test. In this study, we investigated the effect of Mg2⁢ on the responses of dorsal horn neurons to cutaneous thermal stimulation and graded electrical stimulation of afferent nerves as well as to excitatory amino acids and also elucidated whether the actions of Ca2⁢ and Mg2⁢ are...
406.

Evidence for Adenosine Triphosphate (ATP) as an Excitatory Neurotransmitter in Guinea-Pig Gastric Antrum

TongMookKang, WenxieXu, SungJoonKim, SeungCheolAhn, YoungChulKim, InsukSo, MyoungKyuPark, Dae-YongUhm, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 6 165-174 (10 pages)

TongMookKang, WenxieXu, SungJoonKim, SeungCheolAhn, YoungChulKim, InsukSo, MyoungKyuPark, Dae-YongUhm, KiWhanKim 저
...
- 3,000원
We explore the question of whether adenosine 5'-triphosphate (ATP) acts as an excitatory neurotransmitter in guinea-pig gastric smooth muscle. In an organ bath system, isometric force of the circular smooth muscle of guinea-pig gastric antrum was measured in the presence of atropine and guanethidine. Under electrical field stimulation (EFS) at high frequencies (＞20 Hz), NO-mediated relaxation during EFS was followed by a strong contraction after the cessation of EFS (a...
407.

The Effects of Sera from Amyotrophic Lateral Sclerosis Patients on Neuromuscular Transmission and Calcium Channels in Mice

HaiDunYan, JimokKim, SungJunJung, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 17 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 13 101-117 (17 pages)

HaiDunYan, JimokKim, SungJunJung, JunKim 저
...
- 4,600원
Amyotrophic lateral sclerosis (ALS) is a degenerative neuromuscular disease of unknown etiology in which the upper and lower motor neurons are progressively destroyed. Recent evidences support the role of autoimmune mechanisms in the pathogenesis of ALS. This study investigated the effects of sera from ALS patients on neuromuscular transmission in phrenic nerve-hemidiaphragm preparations and on calcium currents of single isolated dorsal root ganglion (DRG) cells in mice. Mice were injected with...
408.

The Roles of Arachidonic Acid and Calcium in the Angiotensin II-induced Inhibition of Na+ Uptake in Renal Proximal Tubule Cells

SooHyunPark, HyunJooKoh, YeunHeeLee, ChangHoSon, MinKyoungPark, YoungJaeLee, HoJaeHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 11 83-91 (9 pages)

SooHyunPark, HyunJooKoh, YeunHeeLee, ChangHoSon, MinKyoungPark, YoungJaeLee, HoJaeHan 저
...
- 3,000원
Angiotensin II (ANG II) has a biphasic effect on Na⁢ transport in proximal tubule: low doses of ANG II increase the Na⁢ transport, whereas high doses of ANG II inhibit it. However, the mechanisms of high dose ANG II-induced inhibition on Na⁢ uptake are poorly understood. Thus the aim of the present study was to investigate signal transduction pathways involved in the ANG II-induced inhibition of Na⁢ uptake in the primary cultured rabbit renal proximal tubule cells (PTCs)...
409.

Regulation of Magnesium Release by cAMP during Chemical Hypoxia in the Rat Heart and Isolated Ventricular Myocytes

JinShangKimAntonioScarpa 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 8 59-68 (10 pages)

JinShangKimAntonioScarpa 저
...
- 3,000원
Chemically induced hypoxia has been shown to induce a depletion of ATP. Since intracellular free Mg2⁢ ([Mg2⁢]i) appears to be tightly regulated following cellular energy depletion, we hypothesized that the increase in [Mg2⁢]i would result in Mg2⁢ extrusion following hormonal stimulation. To determine the relation between Mg2⁢ efflux and cellular energy state in a hypoxic rat heart and isolated myocytes, [Mg2⁢]i, ATP and Mg2⁢ content were measured by...
410.

Role of Adenosine in the Activation of Myocardial Catalase Induced by Brief Regional Ischemia

Young-hoonKim, Chan-hyungKim, Gi-taeKim, HongChoi, Jong-wanPark, Myung-sukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 7 53-57 (5 pages)

Young-hoonKim, Chan-hyungKim, Gi-taeKim, HongChoi, Jong-wanPark, Myung-sukKim 저
...
- 1,500원
The activities of myocardial antioxidant enzymes are known to increase in the hearts preconditioned with the brief episodes of ischemia. This study was undertaken to elucidate the possible involvement of adenosine in the stimulation of myocardial catalase induced by the brief regional ischemia in rabbit hearts. Coronary artery descending the middle anterior wall of left ventricle was occluded for 15 min, followed by 1 hr of reperfusion. Upon reperfusion after the brief ischemia, the activity of...

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