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전체 선택해제
총 448건 검색
본문검색 결과만 보기
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Acyclovir저항성 Herpes Simplex Virus의 복제, DNA합성 및 형질 발현에 미치는 Ganciclovir 및 Vidarabine의 병용효과에 관한 연구
양영태(Young Tai Yang), 정동균(Dong-Kyun Cheong), 모리 마사가즈(Masakazu Mori) 대한약리학회 대한약리학잡지 20 Pages
대한약리학회 대한약리학잡지 1989, 제 25권 제 1호 14 115-134 (20 pages)
Ganciclovir(GCV)와 Vidarabine(ara-A)을 단독으로 또는 동시에 HSV-1에 작용시켰을때 HSV-1의 복제, DNA합성 및 단백질 합성에 미치는 영향을 관찰할 목적으로 본 연구를 시행하였다. 본 실험에서는 4가지의 다른 HSV-1(Wild type KOS, VCVr, IUdRr, 및 PAAr5)를 사용하였다. Virus복제에 미치는 항 virus약의 효과는 Vero 세포단층 배양에서 Yield reduction assay에 의해서 관찰하였다. 항 virus약의 virus DNA 합성에 미치는 영향은 NaI 밀도 구배초원심침전후 H3-표지 virus DNA의 방사능에 의해서 관찰하였다. Virus 단백질의... -
The Effects of Bombesin on the Afferent Sensory Transmission in the Spinal Trigeminal Nucleus of Anesthetized Rats
Shin, Hyung-Cheul, Won, Chung-Kil, Kim, Jun, Park, Hyoung-Jin 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 1호 11 105-112 (8 pages)
The present study was carried out to determine the effects of intracisternal administration of three doses of bombesin (0.001, 0.01 and 0.1 μg) on afferent somatosensory transmission in single neurons of the spinal trigeminal nucleus of anesthetized rats. Lower doses (0.001 μg) of bombegin did not change the afferent sensory transmission. Medium doses (0.01 μg) of bombesin significantly (p p<0.01) facilitated afferent sensory transmission in the 6 to 30 min post-drug period, but higher doses... -
Inhibition of Dicarboxylate Transport by p-chloromercuribenzoic Acid (PCMB) in Plasma Membrane Vesicles of Rabbit Proximal Tubule
Kim, Yong-Keun, Kim, Tae-In, Jung, Jin-Sup, Lee, Sang-Ho 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 2호 8 179-188 (10 pages)
a dose-dependent manner with IC50 of 55 and 65 μM in BBMV and BLMV, respectively. The inhibitory effect of PCMB was prevented by a pretreatment of vesicles with dithiothreitol. PCMB did not increase Na+ permeability at concentrations inhibiting succinate uptake. The PCMB inhibition of succinate uptake was due to a change in Vmax, but not in Km. When membrane vesicles were pretreated with PCMB in the presence of unlabelled succinate, the inhibitory effect was significantly reduced. In both BBMV... -
체위변화가 두부 및 하지의 분시혈류량에 미치는 영향
박원균(Park, Won-Kyun), 채의업(Chae, E-Up) 대한생리학회 대한생리학회지 16 Pages
대한생리학회 대한생리학회지 1985, 제 19권 제 2호 4 139-154 (16 pages)
기립 및 도립의 체위면화가 두부 및 하지의 혈액순환계에 미치는 영향을 관찰하고, atropine의 정주에 의한 부교감신경의 차단이 체위변화에 대한 심맥관계의 내성을 증가시키는 지를 보기위하여 개를 경사대에 수평위로 고정하여 수동적으로 기립 및 도립위로 체위를 변화시키고, 각 체위에서 10분간 유지시켜 경동맥, 외경정맥, 고동맥 및 고정맥의 분시 혈류량, 분시 심박수 및 분시 호흡수, 그리고 혈액의 pH, PCO2, PO2 및 Hct를 측정하였다. 다시 수평위에서 atropine 0.5mg을 1회 정주한 후 위의 실험과정을 반복하여 시행하고... -
Bone inducing effect by recombinant human bone morphogenetic protein-2 and collagen carrier in maxillary sinus of the rabbit
Hyo-Jeong Son, Yeong-Wook Kim, Hong-Jun Hwang, Hyoun-Chull Kim, Sang-Chull Lee, Seung-Hwan O, Jingo Kusukawa, Rhuichiro Tanoue 대한치과이식임플란트학회 Journal of Dental Implant Research 8 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2011, 제 30권 2호 2 115-122 (8 pages)
was able to induce bone regeneration when combined to the carriers. BMPs have potency as alternatives to bone graft and accelators of the new bone formation. Concerned with this study, we thought further investigation are needed about the effective dose and comparative study of the effect of rhBMP-2 on autogenous bone graft, allograft, xenograft, and artificial bone graft or additional study of application of stem cells. (JOURNAL OF THE KOREAN ACADEMY OF IMPLANT DENTISTRY 2011;30(2):115-122) -
Role of Trehalose Synthesis in Ralstonia syzygii subsp. indonesiensis PW1001 in Inducing Hypersensitive Response on Eggplant (Solanum melongena cv. Senryo-nigou)
Nur Laili, Takafumi Mukaihara, Hidenori Matsui, Mikihiro Yamamoto, Yoshiteru Noutoshi, Kazuhiro Toyoda, Yuki Ichinose 한국식물병리학회 The Plant Pathology Journal 14 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 6호 7 566-579 (14 pages)
Ralstonia syzygii subsp. indonesiensis (Rsi, former name: Ralstonia solanacearum phylotype IV) PW1001, a causal agent of potato wilt disease, induces hypersen- sitive response (HR) on its non-host eggplant (Solanum melongena cv. Senryo-nigou). The disaccharide treha- lose is involved in abiotic and biotic stress tolerance in many organisms. We found that trehalose is required for eliciting HR on eggplant by plant pathogen Rsi PW1001. In R. solanacearum, it is known that the OtsA/ OtsB pathway is... -
Suppression of Rice Stripe Virus Replication in Laodelphax striatellus Using Vector Insect-Derived Double-Stranded RNAs
Ying Fang, Jae Young Choi, Dong Hwan Park, Min Gu Park, Jun Young Kim, Minghui Wang, Hyun Ji Kim, Woo Jin Kim, Yeon Ho Je 한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 3호 8 280-288 (9 pages)
RNA interference (RNAi) has attracted attention as a promising approach to control plant viruses in their insect vectors. In the present study, to suppress replication of the rice stripe virus (RSV) in its vector, Laodelphax striatellus, using RNAi, dsRNAs against L. striatellus genes that are strongly upregulated upon RSV infection were delivered through a rice leaf-medi- ated method. RNAi-based silencing of peroxiredoxin, cathepsin B, and cytochrome P450 resulted in significant down regulation... -
Roles of Fungal Volatiles from Perspective of Distinct Lifestyles in Filamentous Fungi
Mohamed El-Agamy Farh, Junhyun Jeon 한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 3호 1 193-203 (11 pages)
Volatile compounds (VOCs) are not only media for communication within a species but also effective tools for sender to manipulate behavior and physiology of receiver species. Although the influence of VOCs on the interactions among organisms is evident, types of VOCs and specific mechanisms through which VOCs work during such interactions are only beginning to become clear. Here, we review the fungal volatile compounds (FVOCs) and their impacts on different recipient or- ganisms from perspective... -
Effect of the Combination Hot Water - Calcium Chloride on the In Vitro Growth of Colletotrichum gloeosporioides and the Postharvest Quality of Infected Papaya
한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 6호 5 572-581 (10 pages)
growth of C. gloesporioides conidia and the quality of infected papaya. In vitro, the HW-Ca treated conidia showed reduced mycelial growth and germination. In vivo, the HW-Ca treatment of infected papaya delayed for 5 days the onset of the anthracnose symptoms and improved the papaya postharvest quality. The combined treatment HW-Ca was better than any of the individual treatments to inhibit the in vitro development of C. gloeosporioides and to reduce the negative effects of papaya anthracnose. -
Selection of Small Synthetic Antimicrobial Peptides Inhibiting Xanthomonas citri subsp. citri Causing Citrus Canker
한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 1호 10 87-94 (8 pages)
Citrus canker disease decreases the fruit quality and yield significantly, furthermore, emerging of streptomycin-resistant pathogens threatens the citrus industry seriously because of a lack of proper control agents. Small synthetic antimicrobial peptides (AMPs) could be a promising alternative. Fourteen hexapeptides were selected by using positional scanning of synthetic peptide combinatorial libraries. Each hexapeptide showed different antimicrobial spectrum against Bacillus, Pseudomonas,...
