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431.

산소유리라디칼이 뇌조직 미크로좀분획의 Na+-K+-ATPase 활성도에 미치는 영향

오세문(Sae Moon Oh)손영숙(Young Sook Son), 최길수(Kil Soo Choi), 임정규(Jung Kyoo Lim), 정명희(Myung Hee Chung) 대한약리학회 대한약리학잡지 14 Pages

대한약리학회 대한약리학잡지 1982, 제 18권 제 2호 1 1-14 (14 pages)

오세문(Sae Moon Oh)손영숙(Young Sook Son), 최길수(Kil Soo Choi), 임정규(Jung Kyoo Lim), 정명희(Myung Hee Chung) 저
...
- 4,300원
중추신경계의 혈관폐쇄 또는 충격손상에 의한 허혈병소에서 진행되는 병리적 변화에 산소유리라디칼이 중요한 역할을 할 것으로 시사되고 있다. 저자는 산소유리라디칼이 뇌조직에 미치는 영향 중 특히 신경세포 정지막전위 유지에 중요한 Na+-K+-ATPase의 활성도에 미치는 영향을 관찰하기 위하여 산틴산화효소 반응계와 뇌조직미크로좀을 이용하여 본 연구를 시행하였다. 미크로좀분획(microsomal fraction)을 산틴과 산틴산화효소와 함께 반응시켰을 때, 분획의 Na+-K+-ATPase의 활성도는 현저한 불활성화를 보인 반면, Mg++-ATPase의...
432.

Pyrantel pamoate 및 Oxantel pamoate 합제(合劑)의 장내선충류(腸內線蟲類)에 대(對)한 구충효과(驅蟲效果)

조승열(Seung-Yull Cho) 대한약리학회 대한약리학잡지 5 Pages

대한약리학회 대한약리학잡지 1976, 제 12권 제 1호 8 69-73 (5 pages)

조승열(Seung-Yull Cho) 저
...
- 1,500원
433.

Functional Changes of Spinal Sensory Neurons Following Gray Matter Degeneration

Park, Sah-Hoon, Park, Jong-Seong, Jeong, Han-Seong 대한생리학회 대한생리학회지 9 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 11 289-297 (9 pages)

Park, Sah-Hoon, Park, Jong-Seong, Jeong, Han-Seong 저
...
- 3,000원
Excitatory amino acids (EAA) are thought to play an important role in producing cell death associated with ischemic and traumatic spinal cord injury. The present study was carried out to determine if the response characteristics of spinal sensory neurons in segments adjacent to degeneration sites induced by EAA are altered following these morphological changes. Intraspinal injections of quisqualic acid (QA) produced neuronal degeneration and spinal cavitation of gray matter. The severity of...
434.

Effects of High Glucose Levels on the Protein Kinase C Signal Transduction Pathway in Primary Cultured Renal Proximal Tubule Cells

Han, Ho-Jae, Kang, Ju-Won, Park, Kwon-Moo 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 8 257-268 (12 pages)

Han, Ho-Jae, Kang, Ju-Won, Park, Kwon-Moo 저
...
- 4,100원
Diabetes mellitus is associated with a wide range of pathophysiologic changes in the kidney. This study was designed to examine the mechanisms by which glucose modulates the expression of polarized membrane transport functions in primary cultured rabbit renal proximal tubule cells. Results are as follows: The rate of 30 minute Rb+ uptake was significantly higher(137.76±5.40%) in primary renal tubular cell cultures treated with 20 mM glucose than that of 5 mM glucose. Not the level of mRNA for...
435.

Cholinergic Role on Insulin Action in Exocrine Secretion of the Isolated Rat Pancreas

Lee, Yun-Lyul, Park, Hyung-Seo, Kim, Myoung-Sub, Kwon, Hyeok-Yil, Park, Hyoung-Jin 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 4 219-230 (12 pages)

Lee, Yun-Lyul, Park, Hyung-Seo, Kim, Myoung-Sub, Kwon, Hyeok-Yil, Park, Hyoung-Jin 저
...
- 4,100원
In order to investigate intra-pancreatic cholinergic roles on insulin action in exocrine secretion, the pancreas was isolated from rats and continuously perfused with modified Krebs-Henseleit solution. Intra-arterial infusion of insulin (100 nM) or cholecystokinin (CCK, 14 pM) alone resulted in stimulation of the volume flow and amylase output. Also insulin potentiated the action of CCK in the exocrine secretion. Tetrodotoxin and atropine completely abolished the potentiating action of insulin...
436.

Effects of Insulin and IGFs on Phosphate Uptake in Primary Cultured Rabbit Renal Proximal Tubule Cells

Han, Ho-Jae, Park, Kwon-Moo 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 7 63-76 (14 pages)

Han, Ho-Jae, Park, Kwon-Moo 저
...
- 4,300원
The aim of present study was to characterize phosphate uptake and to investigate the mechanism for the insulin and insulin-like growth factor(IGF) stimulation of phosphate uptake in primary cultured rabbit renal proximal tubule cells. Results were as follows : 1. The primary cultured proximal tubule cells had accumulated 6.68±0.70 nmole phosphate/mg protein in the presence of 140 mM NaCl and 2.07±0.17 nmole phosphate/mg protein in the presence of 140 mM KCl during a 60 minute uptake period....
437.

Enhanced Expression of Angiotensinogen mRNA in Rat Central and Peripheral Tissues Following Hemorrhage

Do, Eun-Ju, Yang, Eun-Kyoung, Kim, Kyung-Soon, Kim, Suk-Hee, Park, Yoon-Yub, Ahn, Dong-Kuk, Park, Jae-Sik, Lee, Won-Jung 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 8 259-268 (10 pages)

Do, Eun-Ju, Yang, Eun-Kyoung, Kim, Kyung-Soon, Kim, Suk-Hee, Park, Yoon-Yub, Ahn, Dong-Kuk, Park, Jae-Sik, Lee, Won-Jung 저
...
- 3,000원
The renin-angiotensin system plays an important role in the regulation of blood pressure and in body fluid homeostasis. There is increasing evidence for generation of endogenous angiotensin II in many organs and for its role in paracrine functions. Studies were designed to investigate whether hemorrhage produces rapid changes in the gene expression of angiotensinogen in peripheral and brain tissues. Wistar rats received saline drinking water for 7 days, were bled at a rate of 3mlkg-1 min-1 for...
438.

Phorbol Ester-Induced Periodic Contraction in Isolated Rabbit Jugular Vein

Ryu, Jae-Cheol, Jung, Dong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 4 225-232 (8 pages)

Ryu, Jae-Cheol, Jung, Dong-Keun, Lee, Sang-Ho 저
...
- 3,000원
The present study was conducted to evaluate the effect of phorbol 12,13-dibutyrate (PDBu) on the contraction of rabbit jugular vein in vitro. PDBu concentrations of greater than 10 nM induced a periodic contraction which was composed of rapid contraction, plateau and slow relaxation. The frequency of periodic contraction increased as PDBu concentration increased. The PDBu-induced contraction was inhibited by staurosporine (100 nM), it was not changed by tetrodotoxin (1 μM). In Ca2+-free...
439.

Identification of Adenosine 5 -Tetraphosphate in Rabbit Platelets and its Metabolism in Blood

Lee, Joong-Woo, Jeon, Sang-Jun, Kong, In-Deok, Jeong, Seong-Woo 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 3 217-224 (8 pages)

Lee, Joong-Woo, Jeon, Sang-Jun, Kong, In-Deok, Jeong, Seong-Woo 저
...
- 3,000원
Adenosine 5 -tetraphosphate (ATPP) was identified and quantified in extracts of rabbit platelets by elution of extracts containing authentic adenosine 5 -tetraphosphate and comparison of retention time with nucleotide standards using high-performance liquid chromatography technique. The amount of adenosine 5 -tetraphosphate was 0.62 nmoles/109 cells which was 62-fold lower than that of ATP but only 10-fold lower than that of ADP. During platelet aggregation induced by thrombin, adenosine 5...
440.

Effects of Insulin and IGFS on Growth and Functional Differentiation in Primary Cultured Rabbit Kidney Proximal Tubule Cells -Growth and membrane transport-

Han, Ho-Jae, Park, Kwon-Moo, 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 1 191-202 (12 pages)

Han, Ho-Jae, Park, Kwon-Moo, 저
...
- 4,100원
The purpose of this study was to compare effects of insulin and IGFs on growth, apical membrane enzyme activities and membrane transport systems of primary cultured rabbit kidney proximal tubule cells. Results were as follows: 1. Insulin and IGF-I produced significant growth stimulatory effects at 5 X 10-10M. IGF-II(5 X 10 -10 M) did not stimulate significant cell growth. 2. Insulin stimulated the phosphorylation of a 97 KD protein. It was difficult to determine whether this band represents...

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