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The Inhibitory Mechanism of Aloe Glycoprotein (NY945) on the Mediator Release in the Guinea Pig Lung Mast Cell Activated with Antigen-Antibody Complexes
JaiYoulRo, ByungChulLee, MyungHeeChung, SeungKiLee, ChungKiSung, KyungHwanKim, YoungInPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 15 119-131 (13 pages)
mediator re1eases caused by mast cell activation, and a1so aimed to assess the effects of NY945 on the mechanism of mediator re1eases in the mast cell activation. We partially purified mast cell from guinea pig 1ung tissues by using the enzyme digestion, the rough and the discontinuous density percoll gradient method. Mast cells were sensitized with IgG1 (anti-OA) and challenged with ova1bumin. Histamine was assayed by fluorometric ana1yzer, 1eukotrienes by radioimmunoassay. The phospholipase... -
기관근의 수축성에 대한 말초성 Benzodiazepine 수용체의 역할
류한영, 최형철, 최은미, 손의동, 이광윤, 김원준, 하정희 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 18 769-774 (6 pages)
Involvement of Peripheral Benzodiazepine Receptor on the Contractility of Canine Trachealis Muscle. Han Young Rhyu\ Hyung Cheol Choi, Eun Mee Choi, Uy Dong Sohn, Kwang Youn Lee, Won Joon Kim, and Jeoung Hee Ha Department of Phannacology, College of Medicine, Yeungnam University, Taegu 705-035 and lDepartment of Chest Surgery, College of Medicine, Ajou University, Suwon 422- 849, Korea -
α-Adrenergic and Cholinergic Receptor Agonists Modulate Voltage- Gated Ca2+ Channels
Seung-YeolNah, Jae-HaKim, Cheon-HoKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 3 485-493 (9 pages)
We investigated the effect of α-adrenergic and cholinergic receptor agonists on Ca2 current in adult rat trigeminal ganglion neurons using whole-cell patch clamp methods. The application of acetylcholine, carbachol, and oxotremorine (50 ㄍM each) produced a rapid and reversible reduction of the Ca2 current by 17⁑6%, 19⁑3%, and 18⁑4%, respectively. Atropine, a muscarinic antagonist, blocked carbachol- induced Ca2 current inhibition to 3⁑1%.... -
Melatonin Enhances Hepatic Glutathione-peroxidase Activity in Sprague- Dawley Rats
Choong-YongKim, Choong-SoonYun, Dae-HunPark, Woo-SungChoi, JinSukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 12 221-224 (4 pages)
Effects of melatonin on hepatic glutathione-peroxidase (GSH-Px) and glutathione-reductase (GSH-reductase) activities were studied in Sprague-Dawley (SD) rats administered i.p. (10 mg/kg body weight) with melatonin during 15 days. The activity of cytosolic GSH-reductase in the liver was not changed by melatonin. However, melatonin injection increased significantly the activity of liver cytosolic GSH-Px activity compared with those in saline-treated rats. At the same time, plasma GSH-Px was also... -
Platelet-Activating Factor Enhances Interleukin-1 Activity by Alveolar Macrophages Inhibition by PAF Specific Receptor Antagonists
JiheeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 10 201-208 (8 pages)
It is becoming increasingly clear that the inflammatory reaction can be ascribed to a complex array of mediators generated and released from activated phagocytes. In this study, the effect of PAF on interleukin-1(IL-1) activity by rat alveolar macrophages(AM) was examined using thymocyte proliferation assay in the supernate of sample obtained after 24 hr culture. When AM were cultured with PAF alone, no change in IL-1 activity was observed. However, the combined addition of PAF and muramyl... -
Effect of Cisplatin on Sodium-Dependent Hexose Transport in LLC-PK1 Renal Epithelial Cells
SukKyuLee, JeeYeunKim, TaiHyunYu, KyoungRyongKim, KwangHyukKim, YangSaengPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 5 35-43 (9 pages)
Cis-dichlorodiammine platinum II (Cisplatin), an effective chemotherapeutic agent, induces acute renal failure by unknown mechanisms. To investigate direct toxic effects of cisplatin on the renal proximal tubular transport system, LLC-PK1 cell line was selected as a cell model and the sugar transport activity was evaluated during a course of cisplatin treatment. Cells grown to confluence were treated with cisplatin for 60 min, washed, and then incubated for up to 5 days. At appropriate... -
흰쥐 뇌에서 전기경련 충격에 의한 CREB 인산화의 발달단계에 따른 변화
강웅구, 정희연, 안용민, 정선주, 전송희, 박주배, 조수철, 김용식 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 1999, 제 38권 제 3호 16 622-629 (8 pages)
연구목적: 이 논문에서는 뇌에서 전기경련 충격(Electroconvulsive shock, ECS)에 의한 전사인자 CREB의 인산 화를 발달단계에 따라 알아봄으로써 정신장애의 신경발달학적 이해를 위한 생물학적 기반지식을 얻고자 하였다. 방 법: 생후 7, 14, 21일 및 성년 흰쥐에 ECS를 가하고 시간별로 해마 및 소뇌 조직을 얻어 CREB의 인산화를 알아 보기 위해 특이 항체로 면역블롯을 실시하였다. 결 과: 발달단계에 따라 해마에서는 CREB이 감소한 반면 소뇌에서는 CREB이 증가하였다. 기저상태의 CREB 인산화는 해마와 소뇌에서 생후 7일에... -
노화쥐의 해마형성체와 내후각뇌피질에서 세포사 관련물질들의 변화에 대한 면역세포화학적 연구
신수진, 우행원 대한신경정신의학회 신경정신의학 14 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 3호 16 520-533 (14 pages)
연구목적: 학습과 기억에서 중요한 역할을 담당하는 해마형성체(hippocampal formation)와 내후각뇌피질(entorhinal cortex)에서 노화에 따른 세포사 관련물질들의 변화를 살펴보고자 하였다. 방 법: 각각 10마리의 노화쥐와 대조군을 대상으로 NOS, VIP, c-fos, bcl-2, bax, p53에 대한 항체를 사용하여 면 역세포화학염색을 하였고, NOS와 bcl-2의 경우는 면역세포화학 염색이 선명하지 않아 in situ hybridization도 함께 시행하였다. 결 과: 1) NOS 면역반응 신경세포는 노화쥐의 내후각뇌피질에서 대조군에 비해 현저히... -
A Case of Schizophreniform Psychosis in a True Hermaphrodite
Jin-Sook Cheon, Ho -Sung Han 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1995, 제 34권 제 3호 25 907-915 (9 pages)
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알쯔하이머병의 말초 생물학적 지표로서 혈청 Alpha-1-antichymotrypsin
우종인, 이정희, 주진형 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1996, 제 35권 제 6호 25 1467-1475 (9 pages)


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