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451.

Preventive Effect of Polysaccharide of Larimichthys crocea Swim Bladder on Reserpine Induced Gastric Ulcer in ICR Mice

Gui-JieLi, PengSun, RuiWang, Ya-LinZhou, YuQian, XinZhao 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 14 183-190 (8 pages)

Gui-JieLi, PengSun, RuiWang, Ya-LinZhou, YuQian, XinZhao 저
...
- 3,000원
This project’s aim was to determine the reserpine-induced gastric ulcer preventive effect of poly-saccharide of Larimichthys crocea swim bladder (PLCSB) in ICR mice. The anti-gastric ulcer effects of polysaccharide of Larimichthys crocea swim bladder was evaluated in mice model using mor-phological test, serum levels assay, cytokine levels assay, tissue contents analysis, reverse transcrip-tion-polymerase chain reaction (RT-PCR) analysis and western bolt assay. High concentration (50 mg/kg...
452.

The Hepatotoxicity and Testicular Toxicity Induced by Arecoline in Mice and Protective Effects of Vitamins C and E

JianhongZhou, QiSun, ZhirongYang, JieZhang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 8 143-148 (6 pages)

JianhongZhou, QiSun, ZhirongYang, JieZhang 저
...
- 3,000원
Arecoline is a major alkaloid of areca nuts which are widely chewed by southeast Asian and it manifests various toxic effects in different organs of human and animals. In this work, mature mice were treated by vitamins C plus E, arecoline, or both daily for four weeks. The results showed that arecoline significantly increased the levels of serum alkaline phosphatase (ALP), glutamate oxalo-acetate transaminase (GOT), glutamate pyruvate transaminase (GPT) and significantly decreased the levels of...
453.

Alteration of Striatal Tetrahydrobiopterin in Iron-Induced Unilateral Model of Parkinson’s Disease

BijayAryal, Jin-KooLee, , HakRimKim, , Hyung-GunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 6 129-134 (6 pages)

BijayAryal, Jin-KooLee, , HakRimKim, , Hyung-GunKim 저
...
- 3,000원
It has been suggested that transition metal ions such as iron can produce an oxidative injuries to nigrostriatal dopaminergic neurons, like Parkinson’s disease (PD) and subsequent compensative increase of tetrahydrobiopterin (BH4) during the disease progression induces the aggravation of dopaminergic neurodegeneration in striatum. It had been established that the direct administration of BH4 into neuron would induce the neuronal toxicity in vitro. To elucidate a role of BH4 in patho-genesis in...
454.

DA-6034 Induces [Ca2+]i Increase in Epithelial Cells

Yu-MiYang, SoonhongPark, HyeWonJi, Tae-imKim, EungKweonKim, KyungKooKang, DongMinShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 1 89-94 (6 pages)

Yu-MiYang, SoonhongPark, HyeWonJi, Tae-imKim, EungKweonKim, KyungKooKang, DongMinShin 저
...
- 3,000원
DA-6034, a eupatilin derivative of flavonoid, has shown potent effects on the protection of gastric mucosa and induced the increases in fluid and glycoprotein secretion in human and rat corneal and conjunctival cells, suggesting that it might be considered as a drug for the treatment of dry eye. However, whether DA-6034 induces Ca2+ signaling and its underlying mechanism in epithelial cells are not known. In the present study, we investigated the mechanism for actions of DA-6034 in Ca2+...
455.

Naloxone Postconditioning Alleviates Rat Myocardial Ischemia Reperfusion Injury by Inhibiting JNK Activity

AnzhouXia, ZhiXue, WeiWang, TanZhang, TiantianWei, XingzhiSha, YixunDing, WeidongZhou 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.1 9 67-72 (6 pages)

AnzhouXia, ZhiXue, WeiWang, TanZhang, TiantianWei, XingzhiSha, YixunDing, WeidongZhou 저
...
- 3,000원
groups was significantly lower than that in the IR group (p＜0.01). The apoptosis index of cardiomyocytes in the IR group was significantly higher than in the sham group (p＜0.01). The apoptosis indices of cardiomyocytes in all Nal-treated groups were significantly reduced to 55.4%, 26.2%, and 27.6%, respectively, of the IR group (p＜0.01). This study revealed that Naloxone postconditioning before reperfusion inhibits p-JNK expression and decreases cell apoptosis, thus alleviating MIRI.
456.

Advanced Glycation End Products and Diabetic Complications

VarunParkashSingh, AnjanaBali, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.1 1 1-14 (14 pages)

VarunParkashSingh, AnjanaBali, NirmalSingh, AmteshwarSinghJaggi 저
...
- 4,300원
During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation. Protein glycation and formation of advanced glycation end products (AGEs) play an important role in the pathogenesis of diabetic complications like retinopathy, nephropathy, neuropathy, cardiomyopathy along with some other diseases such as rheumatoid arthritis, osteoporosis and aging. Glycation of proteins interferes with...
457.

Functional Characterization of ABCB4 Mutations Found in Low Phospholipid-Associated Cholelithiasis (LPAC)

TaeHeeKim, HyoJinPark, JiHaChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 8 525-530 (6 pages)

TaeHeeKim, HyoJinPark, JiHaChoi 저
...
- 3,000원
which these mutations might change MDR3 transport activity were determined using immunoblotting, cell surface protein biotinylation, and immunofluorescence. Through a membrane vesicular transport assay, we observed that the uptake of paclitaxel was significantly reduced in membrane vesicles expressing 2 ABCB4 mutations, F165I and S320F. Both mutants showed significantly decreased total and cell surface MDR3 expression. These data suggest two missense mutations of ABCB4 may alter function of MDR3...
458.

Effect of ECQ on Iodoacetamide-Induced Chronic Gastritis in Rats

SeEunLee, HyunJuSong, SunYoungPark, YoonjinNam, ChangHoMin, DoYeonLee, JunYeongJeong, HyunSuHa, Hyun-JungKim, WanKyunWhang, JiHoonJeong, In 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 14 469-477 (9 pages)

SeEunLee, HyunJuSong, SunYoungPark, YoonjinNam, ChangHoMin, DoYeonLee, JunYeongJeong, HyunSuHa, Hyun-JungKim, WanKyunWhang, JiHoonJeong, In 저
...
- 3,000원
This study investigated effect of extract containing quercetin-3-O-Ղ-D-glucuronopyranoside from Rumex Aquaticus Herba (ECQ) against chronic gastritis in rats. To produce chronic gastritis, the animals received a daily intra-gastric administration of 0.1 ml of 0.15% iodoacetamide (IA) solution for 7 days. Daily exposure of the gastric mucosa to IA induced both gastric lesions and significant reductions of body weight and food and water intake. These reductions recovered with treatment with...
459.

Antiapoptotic Effect of Paricalcitol in Gentamicin-induced Kidney Injury

SangHeonSuh, KoEunLee, JeongWooPark, InJinKim, OkKim, ChangSeongKim, JoonSeokChoi, EunHuiBae, SeongKwonMa, JongUnLee, SooWanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 9 435-440 (6 pages)

SangHeonSuh, KoEunLee, JeongWooPark, InJinKim, OkKim, ChangSeongKim, JoonSeokChoi, EunHuiBae, SeongKwonMa, JongUnLee, SooWanKim 저
...
- 3,000원
While the anti-apoptotic effect of paricalcitol has been demonstrated in various animal models, it is not yet clear whether paricalcitol attenuates the apoptosis in gentamicin (GM)-induced kidney injury. We investigated the effect of paricalcitol on apoptotic pathways in rat kidneys damaged by GM. Rats were randomly divided into three groups: 1) Control group (n=8), where only vehicle was delivered, 2) GM group (n=10), where rats were treated with GM (150 mg/kg/day) for 7 days, 3) PARI group...
460.

Sex Differences in Hippocampal Neuronal Sensitization by Nicotine in M. gerbils

Young-NaHur, JoonLee, Seung-ChanSohn, Chung-GilWon, Hyung-HaLee, Dong-HoonKim, Sang-HyunChoi, Kyung-HoShin, Boe-GwunChun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 4 405-409 (5 pages)

Young-NaHur, JoonLee, Seung-ChanSohn, Chung-GilWon, Hyung-HaLee, Dong-HoonKim, Sang-HyunChoi, Kyung-HoShin, Boe-GwunChun 저
...
- 1,500원
We studied the sex different nicotine effect on evoked population spike amplitudes (ePSA) and connexin (Cx) expression in the hippocampus CA1 area of gerbils. Acute doses of nicotine bitartrate (0.5 mg/kg: NT-0.5) slightly reduced ePSA in males but markedly augmented that in females. Acute NT (5.0 mg/kg) markedly increased the ePSA in all gerbils. Unlike acute NT-0.5, repeated NT-0.5 injection (twice a day for 7 days) significantly increased the ePSA in males and slightly affected the NT-0.5...

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