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451.

Effects of α1-Adrenergic Receptor Stimulation on Intracellular Na+ Activity and Twitch Force in Guinea-Pig Ventricular Muscles

Chae, Soo-Wan, Gong, Q.Y., Wang, D.Y., Lee, Chin-O. 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 2 203-216 (14 pages)

Chae, Soo-Wan, Gong, Q.Y., Wang, D.Y., Lee, Chin-O. 저
...
- 4,300원
The effects of α1-adrenergic receptor stimulation on membrane potential, intracellular Na+ activity, and twitch force were investigated in ventricular muscles from guinea-pig hearts. Action potentials, intracellular Na+ activity, and twitch force of ventricular papillary muscles were measured simultaneously under various experimental conditions. Stimulation of the α1-adrenergic receptor by phenylephrine produced variable changes in action potential duration, a slight hyperpolarization of the...
452.

Properties of Single K+ Channels of Skeletal Muscle Incorporated into Planar Lipid Bilayer

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 대한생리학회 대한생리학회지 16 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 2 13-28 (16 pages)

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 저
...
- 4,500원
of the open state. Its current-voltage relation was linear in the range of -80 ~ +80 mV. The slope conductance of the substate and open-state were 40 and 144 pS in 0.2 M KCl, respectively. The channel was highly selective for K+ over Cl. The open-state probability was weakly voltage-dependent (e-fold change per 35 mV. The lifetime distributions of open- and closed-states were fitted with two exponentials and the major gating occurred slowly at several hundred milliseconds. Based on the above...
453.

Transformation of Rabbit Proximal Tubule Cells by Strontium Phosphate Transfection with a Plasmid Containing SV4O Early Region Genes

Han, Ho-Jae, Taub, Mary L., 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 14 233-240 (8 pages)

Han, Ho-Jae, Taub, Mary L., 저
...
- 3,000원
In this study, it was investigated whether immortalized proximal tubule cells transformed with pRSVT could survive through the numerous passages. Results were as follows: 1. The cells transfected with pRSVT formed rapidly growing, multilayered colonies within 2 weeks in a hormone defined medium. Domes were also observed in some of the cultures. 2. r-glutamyl transpeptidase activity was equivalent to that observed in primary renal proximal tubule cell cultures. 3. Transformed cells with pRSVT...
454.

Effect of pH on the Vascular Tone and 45Ca Uptake in the Aorta of Spontaneously Hypertensive Rats

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Park, Hae-Kun 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 7 169-180 (12 pages)

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Park, Hae-Kun 저
...
- 4,100원
The effect of extracellular and intracellular pH on vascular tone and 45Ca uptake were investigated in aortic strips and dispersed single aortic smooth muscle cells of spontaneously hypertensive rats (SHR) and aged-matched Wistar-Kyoto rats (WKY). The contraction produced by a change of extracellular pH (pHo) in the range of 6.5 ~ 8.3 was estimated by comparison with the level of vascular tone at pH 7.4. Contraction was induced below pHo 6.5 in WKY, pHo 7.1 in SHR, and over pHo 8.0 on both...
455.

Role of Na+Ca2+ Exchange in the Control of Contractility in Rabbit Basilar Arterial Smooth Muscle

Kim Eui-Yong, Han Jin 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 6 159-168 (10 pages)

Kim Eui-Yong, Han Jin 저
...
- 3,000원
The contraction of rabbit basilar artery was examined as a function of changes in the Na+ electrochemical gradient in order to determine the contribution of Na+/Ca2+ exchange to the modulation of contractility. Ouabain (10-5 M) or K+-free Tyrode solution caused an increase in tonic tension even in the presence of a Ca2+ channel blocker (10-6 M verapamil) and an α-receptor blocker (10-5 M phentolamine). After treatment with ouabain (10-5 M), contractions were augmented by reduction of external...
456.

Calcium-activated Ionic Currents in Smooth Muscle Cells from Rabbit Superior Mesenteric Artery

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 5 151-158 (8 pages)

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 저
...
- 3,000원
Cs+. A Ca2+-activated nonselective cation current was observed in both the depolarized and hyperpolarized potential ranges. And it was blocked by replacement of extracellular Na+ with N-methylglucamine (NMG) or extracellular application of Cd2+. Ca2+-activated Cl- current was revealed in the whole voltage range and was blocked by niflumic acid. These results indicate that at least three kinds of Ca2+-activated ionic currents exist in smooth muscle cells from rabbit superior mesenteric artery.
457.

The Excitatory Mechanism of Substance P in the Antral Circular Muscle of Guinea Pig Stomach

Jun, Jae-Yeoul, Kim, Sung-Joon, Choi, Youn-Baik, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 5 51-60 (10 pages)

Jun, Jae-Yeoul, Kim, Sung-Joon, Choi, Youn-Baik, Kim, Ki-Whan 저
...
- 3,000원
This study was carried out to elucidate the excitatory mechanisms of Substance P in the antral circular muscle, using isometric contraction recording, conventional microelectrode method and whole-cell patch clamp technique. Substance P produced tonic and phasic contractions in a dose-dependent manner and depolarized membrane potential with increased amplitude of slow waves in muscle strips. Voltage-dependent Ca2+ currents were increased by the application of Substance P from a holding potential...
458.

Effects of Lemakalim, a Potassium Channel Opener, on the Contractility and Electrical Activity of the Antral Circular Muscle in Guinea-Pig Stomach

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 4 37-50 (14 pages)

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 저
...
- 4,300원
Synthetic potassium channel openers (KCOs) are agents capable of opening K-channels in excitable cells. These agents are known to have their maximal potency in the smooth muscle tissue, especially in the vascular smooth muscle. Much attention has been focused on the type of K-channel that is responsible for mediating the effects of KCOs. As the KCO-induced changes are antagonized by glibenclamide, an KATP (ATP-sensitive K-channel) blocker in the pancreatic β-cell, KATP was suggested to be the...
459.

Cardiovascular Neurons Mediating Somatosympathetic Reflex in Rostral Ventrolateral Medulla

Goo, Yong-Sook, Kim, Sang-Jeong, Kim, Jun, Sung, Ho-Kyung 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 7 185-198 (14 pages)

Goo, Yong-Sook, Kim, Sang-Jeong, Kim, Jun, Sung, Ho-Kyung 저
...
- 4,300원
The rostral ventrolateral medulla (RVLM) includes vasopressor neurons, which transmit activation signals to the intermediolateral nucleus (IML) of the spinal cord, where the preganglionic sympathetic nucleus is located, to raise arterial blood pressure (BP). However, controversy exists as to the possible depressor area in the RVLM and the pathway involved. The present study persued evidence far the location of depressor neurons and the pathway by simultaneously observing changes in BP and the...
460.

Regulatory Action of ß-adrenergic Agonist and 8-bromocyclic AMP on Calcium Currents in the Unfertilized Mouse Eggs

Haan, Jae-Hee, Cheong, Seung-Jin, Kim, Yang-Mi, Park, Choon-Ok, Hong, Seong-Geun 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 6 175-184 (10 pages)

Haan, Jae-Hee, Cheong, Seung-Jin, Kim, Yang-Mi, Park, Choon-Ok, Hong, Seong-Geun 저
...
- 3,000원
a holding potential of -80 mV, were recorded. The current-voltage (I-V) relation of calcium currents was shown to be bell-shaped; the current began to activate at -50 mV and reached its maximum (-1.33±0.16 nA: mean±S.E., n=7) at -10 mV, then decayed at around 50 mV. Calcium currents were fully activated within 7 ms ~ 20 ms and completely inactivated 200 ms after onset of the step pulse. ISP within the concentration ranges of 10-8 M ~ 10-4 M dose-dependently increased the amplitude calcium...

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