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461.

Matrix Metalloproteinase Inhibitors Attenuate Neuroinflammation Following Focal Cerebral Ischemia in Mice

CheolHongPark, TaeKyeongShin, HoYounLee, SoJungKim, WonSukLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.2 7 115-121 (7 pages)

CheolHongPark, TaeKyeongShin, HoYounLee, SoJungKim, WonSukLee 저
...
- 3,000원
Permanent focal ischemia was induced in the medial frontal and somatosensory cortices by irradiating the skull with cold white light. MMP inhibitors, such as doxycycline, minocycline, and batimastat, significantly reduced the cerebral infarct size, and the expressions of monocyte chemotactic protein-1 (MCP-1), tumor necrosis factor-Ձ (TNF-Ձ), and indoleamine 2,3-dioxygenase (IDO). However, they had no effect on the expressions of heme oxygenase-1 and neuroglobin in the ischemic...
462.

Gender-Related Differences in a Process of the Age-Dependent Alterations of the Elements in Monkey Sino-Atrial Node

HiroyasuSatoh, SetsukoTohno, TakeshiMinami, TakaoOishi, MotoharuHayashi, YoshiyukiTohno 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 1 249-256 (8 pages)

HiroyasuSatoh, SetsukoTohno, TakeshiMinami, TakaoOishi, MotoharuHayashi, YoshiyukiTohno 저
...
- 3,000원
Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30 female) used were aged ranging from 1-day- to 30-year-old. The elements were analyzed using an inductively coupled plasma-atomic emission spectrometer (ICP-AES). Advancing age decreased all the trace elements. Ca, P, S and Mg significantly decreased. The correlation coefficients of Ca and P were...
463.

Neurotrophic and Neuritogenic Effects of Water Extracts of Rhizoma of Coptis chinensis Franch in PC12 Cells

Gee-YounKwon, Byung-KilChoe, Soo-KyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 9 175-179 (5 pages)

Gee-YounKwon, Byung-KilChoe, Soo-KyungKim 저
...
- 1,500원
Coptis chinensis (CC) is one of the traditional herbs used in Oriental medicine for the treatment of gastrointestinal disorders, anxiety, and insomnia. In this study, neurotrophic and neuritogenic effects of CC on rat pheochromocytoma (PC12) cells were evaluated. Pretreatment of PC12 cells with water extracts of CC (120μg /ml) produced considerable outgrowth of neurites that is comparable to the effect of nerve growth factor (NGF). Therefore, neurite outgrowth was quantified and expression of...
464.

Inhibitory and Excitatory Postsynaptic Currents of Medial Vestibular Nucleus Neurons of Rats

SangWooChun, JeongHeeChoi, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 2 59-63 (5 pages)

SangWooChun, JeongHeeChoi, ByungRimPark 저
...
- 1,500원
The medial vestibular nucleus (MVN) neurons are controlled by excitatory synaptic transmission from the vestibular afferent and commissural projections, and by inhibitory transmission from interneurons. Spontaneous synaptic currents of MVN neurons were studied using whole cell patch clamp recording in slices prepared from 13- to 17-day-old rats. The spontaneous inhibitory postsynaptic currents (sIPSCs) were significantly reduced by the GABAA antagonist bicuculline (20μM), but were not affected...
465.

Nimodipine as a Potential Pharmacological Tool for Characterizing R-Type Calcium Currents

SeogBaeOh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.6 8 511-519 (9 pages)

SeogBaeOh 저
...
- 3,000원
Nimopidine, one of dihydropyridine derivatives, has been widely used to pharmacologically identify L-type Ca currents. In this study, it was tested if nimodipine is a selective blocker for L-type Ca currents in sensory neurons and heterologous system. In mouse dorsal root ganglion neurons (DRG), low concentrations of nimodipine (＜10μM), mainly targeting L-type Ca currents, blocked high-voltage-activated calcium channel currents by ∼38%. Interestingly, high concentrations of nimodipine...
466.

Enhanced Expression of Inducible Nitric Oxide Synthase May Be Responsible for Altered Vascular Reactivity in Streptozotocin-induced Diabetic Rats

JaeKwonJang, YoungJinKang, HanGeukSeo, SookJaeSeo, KiChurlChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 2 375-382 (8 pages)

JaeKwonJang, YoungJinKang, HanGeukSeo, SookJaeSeo, KiChurlChang 저
...
- 3,000원
Growing evidence indicates that enhanced generation or actions of nitric oxide (NO) are implicated in the pathogenesis of hypertension in spontaneously hypertensive rats and diabetic nephropathy in streptozotocin (STZ)-induced diabetic rats. We investigated whether inducible nitric oxide synthase (iNOS) expression in STZ-induced diabetic rats is responsible for the alterations of vascular reactivity. Diabetic state was confirmed 28 days after injection of STZ (i.p) in rats by measuring blood...
467.

Effect of pH on the ATP-sensitive K+ Channel in Aortic Smooth Muscle Cells from Rats

SeHoonKim, IlSuKim, HoeSukKim, ByeongHwaJeon, SeokJongChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 11 555-563 (9 pages)

SeHoonKim, IlSuKim, HoeSukKim, ByeongHwaJeon, SeokJongChang 저
...
- 3,000원
The effects of pH on K⁢ currents were investigated in single smooth muscle cells isolated from the thoracic aorta of Wistar-Kyoto rats. Whole-cell K⁢ currents were recorded in the conventional configuration of the voltage-clamp technique. Pinacidil (10uM) activated the whole-cell current and the pinacidil-activated current was completely inhibited by glibenclamide (10uM) , an inhibitor of ATP-sensitive K⁢ channel (KATP channel). Pinacidil-activated current was reversed at near...
468.

가족력 유무에 따른 정신분열병 환자의 뇌척수액 MHPG, HVA 및 5-HIAA 농도에 관한 연구

권준수, 이정희, 홍진표 대한신경정신의학회 신경정신의학 12 Pages

대한신경정신의학회 신경정신의학 1994, 제 33권 제 1호 25 281-292 (12 pages)

권준수, 이정희, 홍진표 저
...
- 4,100원
469.

개구리 세포막에 대한 Racemic Ketamine의 영향

이종화(Jong Hwa Lee), George B. Prank 대한약리학회 대한약리학잡지 10 Pages

대한약리학회 대한약리학잡지 1991, 제 27권 제 2호 2 99-108 (10 pages)

이종화(Jong Hwa Lee), George B. Prank 저
...
- 3,000원
Racemic ketamine을 사용하여 개구리의 좌골신경 및 toe muscle에 대한 작용을 관찰하였다. 실험방법으로는 214 mM sucrose을 사용하여 서로 다른 두 종류의 투여 방법으로 세포막의 활동 전압에 대한 영향을 electric recording으로 관찰하였다. 즉, intracellular 투여는 single sucrose gap technique으로, extracellar 투여는 double sucrose gap technique을 사용하였으며 그 실험 결과는 아래와 같았다. 1. Racemic ketamine은 개구리의 좌골신경 및 toe muscle의 활동전압을 intracellular 및 extracellular 투여시 모두 의의 있게...
470.

콜라겐 차폐막을 이용한 상악동 점막 거대천공 재건술: 후향적 임상연구

강동우, 김영균 대한치과이식임플란트학회 Journal of Dental Implant Research 5 Pages

대한치과이식임플란트학회 Journal of Dental Implant Research 2017, 제 36권 1호 1 1-5 (5 pages)

강동우, 김영균 저
...
- 1,500원
상악동 거상술(Sinus lift)은 상악동 함기화(pneumatization), 치조골 퇴축 혹은 외상 등으로 인해 심각한 치조골 소실이 존재하는 상악골 후방 부위에서 수직적 골체적을 증가시키기 위해 자주 시행 하는 술식이다. 상악동 거상술 시행 중 가장 많이 발생하는 합병증은 상악동 점막의 천공이며, 천공 빈도는 문헌에 따라 14∼56%까지 매우 다양하게 보고되고 있다1-3). 상악동 점막의 천공은 주로 절삭기 구나 점막거상 기구를 부적절하게 사용할 때 혹은 점막 자체가 얇다 든지 상악동 격벽(sinus septa)이 존재하는 경우에 발생할 수...

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