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41.

A Simple Dosing Scheme for Intravenous Busulfan Based on Retrospective Population Pharmacokinetic Analysis in Korean Patients

SangminChoe, GayeongKim, Hyeong-SeokLim, Sang-HeonCho, Jong-LyulGhim, JinAhJung, Un-JibKim, GyujeongNoh, Kyun-SeopBae, DonghoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 7 273-280 (8 pages)

SangminChoe, GayeongKim, Hyeong-SeokLim, Sang-HeonCho, Jong-LyulGhim, JinAhJung, Un-JibKim, GyujeongNoh, Kyun-SeopBae, DonghoLee 저
...
- 3,000원
Busulfan is an antineoplastic agent with a narrow therapeutic window. A post-hoc population pharmacokinetic analysis of a prospective randomized trial for comparison of four-times daily versus once-daily intravenous busulfan was carried out to search for predictive factors of intravenous busulfan (iBu) pharmacokinetics (PK). In this study the population PK of iBu was characterized to provide suitable dosing recommendations. Patients were randomized to receive iBu, either as 0.8 mg/kg every 6 h...
42.

A Computational Model of Cytosolic and Mitochondrial [Ca2＋] in Paced Rat Ventricular Myocytes

JaeBoumYoum, SeongWooChoi, ChangHanJang, HyoungKyuKim, ChaeHunLeem, NariKim, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 23 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.4 5 217-239 (23 pages)

JaeBoumYoum, SeongWooChoi, ChangHanJang, HyoungKyuKim, ChaeHunLeem, NariKim, JinHan 저
...
- 5,200원
We carried out a series of experiment demonstrating the role of mitochondria in the cytosolic and mitochondrial Ca2＋ transients and compared the results with those from computer simulation. In rat ventricular myocytes, increasing the rate of stimulation (1∼3 Hz) made both the diastolic and systolic [Ca2＋] bigger in mitochondria as well as in cytosol. As L-type Ca2＋ channel has key influence on the amplitude of Ca2＋-induced Ca2＋ release, the relation between stimulus frequency and the...
43.

Effects of Zinc on Spontaneous Miniature GABA Release in Rat Hippocampal CA3 Pyramidal Neurons

Byung-JuChoi, Il-SungJang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.2 1 59-64 (6 pages)

Byung-JuChoi, Il-SungJang 저
...
- 3,000원
retained functional presynaptic nerve terminals. The spontaneous miniature excitatory and inhibitory postsynaptic currents (mEPSCs and mIPSCs, respectively) were pharmacologically isolated and recorded using whole-cell patch clamp technique under voltage-clamp conditions. Zn2⁢ at a lower concentration (30μM) increased GABAergic mIPSC frequency without affecting mIPSC amplitude, but it decreased both mIPSC frequency and amplitude at higher concentrations (≥300μM). In contrast, Zn2⁢...
44.

Role of Stretch-Activated Channels in Stretch-Induced Changes of Electrical Activity

JaeBoumYoum, Su-HyunJo, ChaeHunLeem, Won-KyungHo, YungE. 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 6 33-41 (9 pages)

JaeBoumYoum, Su-HyunJo, ChaeHunLeem, Won-KyungHo, YungE. 저
...
- 3,000원
We developed a cardiac cell model to explain the phenomenon of mechano-electric feedback (MEF), based on the experimental data with rat atrial myocytes. It incorporated the activity of ion channels, pumps, exchangers, and changes of intracellular ion concentration. Changes in membrane excitability and Ca2⁢ transients could then be calculated. In the model, the major ion channels responsible for the stretch-induced changes in electrical activity were the stretch-activated channels (SACs)....
45.

Relatoinship between Sarcoplasmic Reticular Calcium Release and Na+-Ca2+ Exchange in the Rat Myocardial Contraction

Eun-GiKim, SoonJinKim, ChangMannKo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 4 197-210 (14 pages)

Eun-GiKim, SoonJinKim, ChangMannKo 저
...
- 4,300원
Suppressive role of Na⁢-Ca2⁢ exchange in myocardial tension generation was examined in the negative frequency-force relationship (FFR) of electric field stimulated left atria (LA) from postnatal developing rat heart and in the whole-cell clamped adult rat ventricular myocytes with high concentration of intracellular Ca2⁢ buffer (14 mM EGTA). LA twitch amplitudes, which were suppressed by cyclopiazonic acid in a postnatal age-dependent manner, elicited frequency-dependent and...
46.

뇌손상 후 신경정신과적 증상이 있는 환자에서 전산화 뇌파 검사의 임상적 유용성

배종훈, 강용갑, 정문용 대한신경정신의학회 신경정신의학 13 Pages

대한신경정신의학회 신경정신의학 1995, 제 34권 제 1호 12 126-138 (13 pages)

배종훈, 강용갑, 정문용 저
...
- 4,200원
47.

憂駿症의 症候學的硏究第四編, 內因性 및 反應性憂懲症의 鑑別診斷올 위한 統計的試圖

金光日, 高應鱗 대한신경정신의학회 신경정신의학 13 Pages

대한신경정신의학회 신경정신의학 1979, 제 18권 제 1호 2 9-21 (13 pages)

金光日, 高應鱗 저
...
- 4,200원
48.

치아-임프란트 지지 가철성 국소의치에서 하악골에서 발생하는 응력의 광탄성학적 분석

정다운, 심혜영 대한치과이식임플란트학회 Journal of Dental Implant Research 19 Pages

대한치과이식임플란트학회 Journal of Dental Implant Research 2009, 제 28권 2호 2 10-28 (19 pages)

정다운, 심혜영 저
...
- 4,800원
하악의 대구치는 저작의 중추적인 역할을 하는 부위로 맹출 이후 가장 많은 교합력을 받는 부위이다. 이로 인해, 구강내에서 가장 먼저 상실되는 치아이기도 하다1,2). 하악에서 양측성으로 구치부가 탈락하여 후방연장 국소 의치를 제작하는 경우 많은 임상적인 문제점이 발생한다. 유리단 부위 치조제의 계속적인 흡수, 구치부의 불안정 으로 인한 교합의 부조화, 연조직의 통증 등이 발생하게 된다3-6). 이는 후방연장 국소의치의 역학적인 불리함에 서 기인한다고 할 수 있다7). 유리단 부위가 길어질수록 mechanical advantage는...
49.

Finite element stress analysis of internal implant/abutment connection according to different apical-coronal implant position

Su-Gwan Kim, Dong-Cook Choi, Byung-Ock Kim, Sang-Ho Oh 대한치과이식임플란트학회 Journal of Dental Implant Research 8 Pages

대한치과이식임플란트학회 Journal of Dental Implant Research 2004, 제 23권 1호 4 32-39 (8 pages)

Su-Gwan Kim, Dong-Cook Choi, Byung-Ock Kim, Sang-Ho Oh 저
...
- 3,000원
The supracrestal apical-coronal positioning of the implant collar improves the clinical crown/implant ratio and the implant anchorage surface. The combination of a rough surface and a supracrestal apical-coronal position considerably increases the implant anchorage1). The disadvantages of supracrestal apical-coronal positioning are that osseointegration can fail owing to overload; failure can result owing to insufficient primary stability; metal may become exposed in the aesthetic zone (anterior...
50.

Current Classification of the Bacillus pumilus Group Species, the Rubber- Pathogenic Bacteria Causing Trunk Bulges Disease in Malaysia as Assessed by MLSA and Multi rep-PCR Approaches

Ainur Ainiah Azman Husni, Siti Izera Ismail, Noraini Md. Jaafar, Dzarifah Zulperi 한국식물병리학회 The Plant Pathology Journal 15 Pages

한국식물병리학회 The Plant Pathology Journal 2021, 37권 3호 4 243-257 (15 pages)

Ainur Ainiah Azman Husni, Siti Izera Ismail, Noraini Md. Jaafar, Dzarifah Zulperi 저
...
- 4,400원
Bacillus pumilus is the causal agent of trunk bulges dis- ease affecting rubber and rubberwood quality and yield production. In this study, B. pumilus and other closely related species were included in B. pumilus group, as they shared over 99.5% similarity from 16S rRNA analysis. Multilocus sequence analysis (MLSA) of five housekeeping genes and repetitive elements-based poly- merase chain reaction (rep-PCR) using REP, ERIC, and BOX primers conducted to analyze the diversity and systematic...

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