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41.

Prolyl 4 Hydroxylase: A Critical Target in the Pathophysiology of Diseases

RaviKant, AnjanaBali, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.2 1 111-120 (10 pages)

RaviKant, AnjanaBali, NirmalSingh, AmteshwarSinghJaggi 저
...
- 3,000원
Prolyl 4 hydroxylases (P4H) are iron- and 2-oxoglutamate-dependent dioxygenase enzymes and hypoxia-inducible transcription factor (HIF)-P4Hs play a critical role in the regulating oxygen homeostasis in the local tissues as well in the systemic circulation. Over a period of time, a number of prolyl hydroxylase inhibitors and activators have been developed. By employing the pharmacological tools and transgenic knock out animals, the critical role of these enzymes has been established in the...
42.

Impact of Micellar Vehicles on in situ Intestinal Absorption Properties of Beta-Lapachone in Rats

SoungBaekJang, DongjuKim, SeongYeonKim, ChangheePark, JiHoonJeong, Hyo-JeongKuh, JaehwiLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 2 9-13 (5 pages)

SoungBaekJang, DongjuKim, SeongYeonKim, ChangheePark, JiHoonJeong, Hyo-JeongKuh, JaehwiLee 저
...
- 1,500원
The aim of the present study was to examine the effect of micellar systems on the absorption of beta-lapachone (b-lap) through different intestinal segments using a single-pass rat intestinal perfusion technique. B-lap was solubilized in mixed micelles composed of phosphatidylcholine and sodium deoxycholate, and in sodium lauryl sulfate (SLS)-based conventional micelles. Both mixed micelles and SLS micelles improved the in situ permeability of b-lap in all intestinal segments tested although the...
43.

Sustained K＋ Outward Currents are Sensitive to Intracellular Heteropodatoxin2 in CA1 Neurons of Organotypic Cultured Hippocampi of Rats

Sung-CherlJung, Su-YongEun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.5 9 343-348 (6 pages)

Sung-CherlJung, Su-YongEun 저
...
- 3,000원
Blocking or regulating K+ channels is important for investigating neuronal functions in mammalian brains, because voltage-dependent K+ channels (Kv channels) play roles to regulate membrane excitabilities for synaptic and somatic processings in neurons. Although a number of toxins and chemicals are useful to change gating properties of Kv channels, specific effects of each toxin on a particular Kv subunit have not been sufficiently demonstrated in neurons yet. In this study, we tested...
44.

Development of Estimation Methods of Skin Oxidation and Evaluation of Anti-Oxidative Effects of Genistein in Topical Formulations

SeongYeonKim, YeonJooNa, DongjuKim, YeongseokKim, HyeongMinKim, Sung-HaHwang, JiyeonKwak, Hyo-JeongKuh, JaehwiLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 9 205-209 (5 pages)

SeongYeonKim, YeonJooNa, DongjuKim, YeongseokKim, HyeongMinKim, Sung-HaHwang, JiyeonKwak, Hyo-JeongKuh, JaehwiLee 저
...
- 1,500원
The objective of the present study was to establish the method of measurement of hydrogen peroxide and to estimate the anti-oxidative effect of genistein in the skin. UVB induced skin oxidation and anti-oxidative effect of genistein formulations were evaluated by determining levels of hydrogen peroxide. The mechanism involved in the determination of hydrogen peroxide is based on a color reaction between ferric ion (Fe3＋) and xylenol orange, often called FOX assay and subsequent monitoring of...
45.

靑少年犯罪類型과 韓國家族形態間의 關係

金憲秀, 聞秉根, 金賢實 대한신경정신의학회 신경정신의학 20 Pages

대한신경정신의학회 신경정신의학 1996, 제 35권 제 3호 9 574-593 (20 pages)

金憲秀, 聞秉根, 金賢實 저
...
- 4,900원
46.

Nomifensine이 가토 혈중 주정농도에 미치는 영향에 관한 실험적 연구

이혜련 대한신경정신의학회 신경정신의학 7 Pages

대한신경정신의학회 신경정신의학 1982, 제 21권 제 1호 16 137-143 (7 pages)

이혜련 저
...
- 3,000원
47.

흰쥐 태 뇌간의 세포배양에서 HPLC-전기화학검출을 이용한 Tyrosine Hydroxylase 활성 및 Dopamine의 정량

송동근(Dong-Keun Song), 위명복(Myung-Bok Wie), 박찬웅(Chan-Woong Park), 김영희(Yung-Hi Kim) 대한약리학회 대한약리학잡지 6 Pages

대한약리학회 대한약리학잡지 1991, 제 27권 제 1호 2 7-12 (6 pages)

송동근(Dong-Keun Song), 위명복(Myung-Bok Wie), 박찬웅(Chan-Woong Park), 김영희(Yung-Hi Kim) 저
...
- 3,000원
쥐(태령 14일) 뇌간 세포배양에서 발달과정에 따른 Tyrosine hydroxylase(TH) 활성 및 dopamine의 양적 증가를 전기화학 HPLC를 이용하여 측정하였다. TH 활성 및 dopamine의 양은 배양 7일까지 점차 증가하였다. 배양 7일째에 여러 약물들의 dopamine 대사에 대한 영향을 조사하였다. TH 억제제인 α-methyl-p-tyrosine 및 aromatic amiono acid decarboxylase 억제제인 NSD-1015는 효과적으로 dopamine을 고갈시켰다. Dopamine은 reserpine에 의해 고갈되었고, parglyine에 의해 증가되었다. 일주일 배양한 세포의 배양액에...
48.

사람의 백혈구 내에 있는 Elestase: 순수부리, 금속이온의 화학량, 그리고 Chelating 효과에 의한 활성도 조절

강구일(Koo-Il Kang) 대한약리학회 대한약리학잡지 14 Pages

대한약리학회 대한약리학잡지 1988, 제 24권 제 1호 12 111-124 (14 pages)

강구일(Koo-Il Kang) 저
...
- 4,300원
사람의 혈액으로부터 Elastase를 분리하는 새로운 방법을 개발하여 순도 높은 효소를 얻고 이 효소에 의하여 발생되어지는 질병의 예방과 치료에 응용하기 위하여 이 효소의 근본적인 성질규명을 시도하였다. 정제 방법으로는 Sephodex G-75를 이용한 1회의 액체 크로마토그라피와 HPLC을 이용한 2회의 코마토그라피를 거치는 2단계 방법을 사용하였다. 이때 얻어진 효소는 분자량이 26,000 ~ 29,700 사이에 있는 3개의 다른 분자량을 가진 물질로 확인되었으며, 항체 반응에서 사람의 결구내 Elastase의 특성을 나타내었다. 함유하고...
49.

Properties of Single K+ Channels of Skeletal Muscle Incorporated into Planar Lipid Bilayer

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 대한생리학회 대한생리학회지 16 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 2 13-28 (16 pages)

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 저
...
- 4,500원
single K+ channels of skeletal muscle from the rat and frog were into planar lipid bilayers and their properties were studied. Fusion was induced by an osmotic gradient. Of the four types of K+ channels recorded, the two most frequently observed were a voltage and Ca2+-activated K+ channel and a K+ channel with a prominent conductance substate. The first K+ channel was identified as the large Ca2+-activated K+ (BK) channel because the open-state probability was increased with depolarization...
50.

Preparation of Nanomaterial Wettable Powder Formulations of Antagonistic Bacteria from Phellodendron chinense and the Biological Control of Brown Leaf Spot Disease

Yanling Zeng, Han Liu, Tianhui Zhu, Shan Han, Shujiang Li 한국식물병리학회 The Plant Pathology Journal 17 Pages

한국식물병리학회 The Plant Pathology Journal 2021, 37권 3호 2 215-231 (17 pages)

Yanling Zeng, Han Liu, Tianhui Zhu, Shan Han, Shujiang Li 저
...
- 4,600원
Brown leaf spot disease caused by Nigrospora guilin- ensis on Phellodendron chinense occurs in a large area in Dayi County, Chengdu City, Sichuan Province, China each year. This outbreak has severely reduced the production of Chinese medicinal plants P. chinense and caused substantial economic losses. The bacterial isolate JKB05 was isolated from the healthy leaves of P. chinense, exhibited antagonistic effects against N. guilinensis and was identified as Bacillus megaterium. The following...

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