학지사 뉴논문

총 544건 검색

본문검색 결과만 보기

정확도순

최신순

등재순

발행기간

전체
최근 1년
최근 3년
직접입력

적용하기

본문검색

포함

제외

10개씩

491.

Heparin Attenuates the Expression of TNFα-induced Cerebral Endothelial Cell Adhesion Molecule

JeongHoLee, ChulHoonKim, GiHoSeo, JinuLee, JooHeeKim, DongGooKim, YoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.5 3 231-236 (6 pages)

JeongHoLee, ChulHoonKim, GiHoSeo, JinuLee, JooHeeKim, DongGooKim, YoungSooAhn 저
...
- 3,000원
Heparin is a well-known anticoagulant widely used in various clinical settings. Interestingly, recent studies have indicated that heparin also has anti-inflammatory effects on neuroinflammation-related diseases, such as Alzheimer's disease and meningitis. However, the underlying mechanism of its actions remains unclear. In the present study, we examined the anti-inflammatory mechanism of heparin in cultured cerebral endothelial cells (CECs), and found that heparin inhibited the tumor necrosis...
492.

Neuroprotective Effects of Methanol Extracts of Jeju Native Plants on Hydrogen Peroxide-induced Cytotoxicity in SH-SY5Y Human Neuroblastoma Cells

Pil-JaeKong, Yu-MiKim, HeeJaeLee, Sung-SooKim, EunSookYoo, WanjooChun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.5 2 170-174 (5 pages)

Pil-JaeKong, Yu-MiKim, HeeJaeLee, Sung-SooKim, EunSookYoo, WanjooChun 저
...
- 1,500원
chinesis significantly decreased hydrogen peroxide-induced apoptotic cell death. The extracts attenuated hydrogen peroxide (H2O2)-induced caspase-3 activation in a dose-dependent manner. Further, plant extracts restored H2O2-induced depletion of intracellular glutathione, a major endogenous antioxidant. The data suggest that Jeju native medicinal plants could potentially be used as therapeutic agents for treating or preventing neurodegenerative diseases in which oxidative stress is implicated.
493.

Effects of Repeated Nicotine Treatment on the Changes in Glutamate Receptor Subunits Levels in Mesocorticolimbic Dopamine Areas

Kuem-JuLee, Dong-HoonKim, Song-HyenChoi, You-ChanShin, Sang-HaPark, Bo-HyunMoon, SeungWooKang, EujinCho, Sang-HyunChoi, Boe-GwunChun, Min- 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.4 1 139-144 (6 pages)

Kuem-JuLee, Dong-HoonKim, Song-HyenChoi, You-ChanShin, Sang-HaPark, Bo-HyunMoon, SeungWooKang, EujinCho, Sang-HyunChoi, Boe-GwunChun, Min- 저
...
- 3,000원
Recent studies suggest that alterations in glutamate receptor subunit levels in mesocorticolimbic dopamine areas could account for neural adaptations in response to psychostimulant drugs. Although many drugs of abuse induce changes in ionotropic glutamate receptor subunits in mesocorticolimbic dopamine areas, the changes of ionotropic glutamate receptor subunits by repeated nicotine treatment in these areas are not known. To answer this question, we injected male Sprague-Dawley rats twice daily...
494.

Alternative Isoforms of TonEBP with Variable N-termini are Expressed in Mammalian Cells

HyoShinKim, SookJinSon, SeonNyoKim, YongDukKim, KwangJinKim, ByeongHwaJeon, JinBongPark, SangDoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 9 135-138 (4 pages)

HyoShinKim, SookJinSon, SeonNyoKim, YongDukKim, KwangJinKim, ByeongHwaJeon, JinBongPark, SangDoLee 저
...
- 1,500원
of stress to cells since it causes rise in cellular ionic strength, which can be reduced by the accumulation of compatible osmolytes. TonEBP plays a central role in the cellular accumulation of compatible osmolytes via transcriptional stimulation of membrane transporters and aldose reductase. Alternatively spliced forms of TonEBP mRNA have previously been reported and two of them showed different transcriptional activity. In the present study, isoform-specific antibodies were produced to confirm...
495.

Developmental Disability Animal Model Based on Neonatal Lipopolysaccharide with Altered 5-HT Function

JaeGooKim, MinSooKim, SeoulLee, GunTaeKim, JongDooLee, DongGooKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 6 113-119 (7 pages)

JaeGooKim, MinSooKim, SeoulLee, GunTaeKim, JongDooLee, DongGooKim 저
...
- 3,000원
Developmental disability shows life-long behavioral abnormality with no significant physical malformation. This study was undertaken to develop an animal model for developmental disability by using two-factor approach. Lipopolysaccharide (LPS), a bacterial toxin, and NAN-190, a 5-HT1A receptor antagonist, were administered to Sprague-Dawley rats on postnatal day (PND) 5 to induce inflammation and an altered 5-HT system, respectively. Long-term alteration of behavior occurred in the drug-treated...
496.

A1 Receptor-mediated Protection against Amyloid Beta-induced Injury in Human Neuroglioma Cells

YongWoonCho, HyunJuJung, YongKeunKim, JaeSukWoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.2 1 37-43 (7 pages)

YongWoonCho, HyunJuJung, YongKeunKim, JaeSukWoo 저
...
- 3,000원
Adenosine has been reported to provide cytoprotection in the central nervous systems as well as myocardium by activating cell surface adenosine receptors. However, the exact target and mechanism of its action still remain controversial. The present study was performed to examine whether adenosine has a protective effect against Aβ-induced injury in neuroglial cells. The astrocyte-derived human neuroglioma cell line, A172 cells, and Aβ25∼35 were employed to produce an experimental Aβ-induced...
497.

The Role of Janus Kinase in Superoxide-mediated Proliferation of Diabetic Vascular Smooth Muscle Cells

JiYoungLee, JiYoungPark, ChiDaeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.1 5 31-36 (6 pages)

JiYoungLee, JiYoungPark, ChiDaeKim 저
...
- 3,000원
To elucidate a potential molecular link between diabetes and atherosclerosis, we investigated the role of Janus tyrosine kinase (JAK) for NAD(P)H oxidase-derived superoxide generation in the enhanced proliferative capacity of vascular smooth muscle cells (VSMC) of Otsuka Long-Evans Tokushima Fatty (OLETF) rat, an animal model of type 2 diabetes. An enhanced proliferative response to 10% fetal bovine serum (FBS) and superoxide generation with an increased NAD(P)H oxidase activity were observed in...
498.

The Effect of Dehydroepiandrosterone on Isoproterenol-induced Cardiomyopathy in Rats

JiHoonJeong, ChanWoongKim, SungHyukYim, YongKyooShin, KyungWhaPark, EonSubPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.2 4 79-84 (6 pages)

JiHoonJeong, ChanWoongKim, SungHyukYim, YongKyooShin, KyungWhaPark, EonSubPark 저
...
- 3,000원
creatine kinase (CK-MB) induced by isoproterenol. We also assayed widely used oxidative stress parameters, including thiobarbituric acid reactive substances (TBARS), superoxide dismutase (SOD), catalase and glutathion peroxidase (GPx). DHEA decreased the escalated level of TBARS and enhanced the anti oxidant defense reaction with an increase in Mn-SOD and Cu/Zn-SOD. On the other hand, the treatment with DHEA did not affect catalase and GPx activity. The present study indicates that DHEA has a...
499.

YS 49, a Synthetic Isoquinoline Alkaloid, Protects Sheep Pulmonary Artery Endothelial Cells from tert-butylhydroperoxide-mediated Cytotoxicity

WonSeogChong, SunYoungKang, YoungJinKang, MinKyuPark, YoungSooLee, HyeJungKim, HanGeukSeo, JaeHeunLee, HyeSookYun-Choi, KiChurlChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.5 5 283-290 (8 pages)

WonSeogChong, SunYoungKang, YoungJinKang, MinKyuPark, YoungSooLee, HyeJungKim, HanGeukSeo, JaeHeunLee, HyeSookYun-Choi, KiChurlChang 저
...
- 3,000원
Endothelium, particularly pulmonary endothelium, is predisposed to injury by reactive oxygen species (ROS) and their derivatives. Heme oxygenase (HO) has been demonstrated to provide cytoprotective effects in models of oxidant-induced cellular and tissue injuries. In the present study, we investigated the effects of YS 49 against oxidant [tert-butylhydroperoxide (TBH)]-induced injury using cultured sheep pulmonary artery endothelial cells (SPAECs). The viability of SPAECs was determined by...
500.

Inhibition of Angiotensin II-Induced Vascular Smooth Muscle Cell Hypertrophy by Different Catechins

YingZheng, HyeJinSong, SeokHeeYun, YeonJeongChae, HaoJia, ChanHyungKim, TaeSunHa, AgapiosSachinidis, HeeYulAhn, SraT.Davidge 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 7 117-124 (8 pages)

YingZheng, HyeJinSong, SeokHeeYun, YeonJeongChae, HaoJia, ChanHyungKim, TaeSunHa, AgapiosSachinidis, HeeYulAhn, SraT.Davidge 저
...
- 3,000원
A cumulative evidence indicates that consumption of tea catechin, flavan-3-ol derived from green tea leaves, lowers the risk of cardiovascular diseases. However, a precise mechanism for this cardiovascular action has not yet been fully understood. In the present study, we investigated the effects of different green tea catechins, such as epigallocatechin-3 gallate (EGCG), epigallocatechin (EGC), epicatechin-3 gallate (ECG), and epicatechin (EC), on angiotensin II (Ang II)-induced hypertrophy in...

한주간 이슈검색어