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491.

Electrophysiological Responses of δ -Opioid Receptor Expressed on HEK293 Cells

Kim, Jin-Hyuk, Koh, Young-Ik, Chin, He-Min, Lee, Yong-Sung, Cho, Yeul-Hee, Kim, Kee-Soon 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 12 301-308 (8 pages)

Kim, Jin-Hyuk, Koh, Young-Ik, Chin, He-Min, Lee, Yong-Sung, Cho, Yeul-Hee, Kim, Kee-Soon 저
...
- 3,000원
of the transformed HEK293 cells with 1 mM 8-bromo-cyclic AMP, DPDPE failed to increase the voltage sensitive outward currents. On the other hand, naloxone completely abolished DPDPE-activated voltage sensitive outward current in the transformed HEK293 cells. The results of present study suggest that in the transformed HEK293 cells an activation of the δ-Opioid receptors by an opioid agonist DPDPE increases the voltage-sensitive potassium current as a result of decrement in cyclic AMP level.
492.

Contractile and Electrical Responses of Guinea-pig Gastric Smooth Muscle to Bradykinin

Kim, Chul-Soo, Jun, Jae-Yeoul, Kim, Sung-Joon, So, In-Suk, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 5 233-242 (10 pages)

Kim, Chul-Soo, Jun, Jae-Yeoul, Kim, Sung-Joon, So, In-Suk, Kim, Ki-Whan 저
...
- 3,000원
The nonapeptide bradykinin has been shown to exhibit an array of biological activities including relaxation/contraction of various smooth muscles. In order to investigate the effects of bradykinin on the contractility and the electrical activity of antral circular muscle of guinea-pig stomach, the isometric contraction and membrane potential were recorded. Also, using standard patch clamp technique, the Ca2+-activated K currents were recorded to observe the change in cytosolic Ca2+...
493.

Phorbol Ester-Induced Periodic Contraction in Isolated Rabbit Jugular Vein

Ryu, Jae-Cheol, Jung, Dong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 4 225-232 (8 pages)

Ryu, Jae-Cheol, Jung, Dong-Keun, Lee, Sang-Ho 저
...
- 3,000원
channel blockers, did not affect the PDBu-induced periodic contraction, whereas tetraethylammonium (TEA) abolished the periodicity. Pinacidil (10 μM)., a potassium channel activator, blocked PDBu induced periodic contraction, which was recovered by glybenclamide (10 μM).. In high potassium solution, PDBu did not produce the periodic contraction. These results suggest that the PDBu-induced periodicity of contraction is modulated by voltage dependent Ca2+ channel and ATP-sensitive K+ channel.
494.

The Action of Ginkgo Bibloba Extract in the Isolated Rabbit Corpus Cavernosum

Chung, Woo-Sik, Choi, Young-Deuk, Park, Young-Yo, Hah, Jong-Sik 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 6 61-68 (8 pages)

Chung, Woo-Sik, Choi, Young-Deuk, Park, Young-Yo, Hah, Jong-Sik 저
...
- 3,000원
The extract of Ginkgo bibloba (EGb) is a complex mixture of natural products from the Ginkgo leaves and clinically used for the treatment of cerebral and peripheral circulatory disturbances due to its combined activity of several vasoactive principles. In this study we investigated the action of EGb and its mechanism in isolated rabbit corporal smooth muscle to evaluate the possibility of using this material as a pharmacoerecting agent. Strips of rabbit corpus cavernosum were mounted in organ...
495.

Effect of Cyclic Nucleotides on Phorbol Ester-Induced Contraction in Rabbit Carotid Artery

Jung, Dong-Keun, Woo, Jae-Suk, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 4 39-50 (12 pages)

Jung, Dong-Keun, Woo, Jae-Suk, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 저
...
- 4,100원
(PKC). 45Ca2+ uptake by rabbit carotid artery was increased by PDBu during depolarization, but not in control. Isoproterenol and sodium nitroprusside (SNP) relaxed phenylephrine-induced contraction. However, SNP but not isoproterenol relaxed the contraction induced by PDBu. Acetylcholine relaxed PDBu-induced contraction in the presence of the endothelium. 8-bromo-cyclic AMP, a permeable analogue of cyclic AMP, suppressed phenylephrine-induced contraction but not PDBu-induced contraction. 8-bromo...
496.

Calcium Current in the Unfertilized Egg of the Hamster

Haan, Jae-Hee, Cho, Soo-Wan, Yang, Young-Sun, Park, Young-Geun, Park, Hong-Gi, Chang, Gyeong-Jae, Kim, Yang-Mi, Park, Choon-Ok, Hong, Se 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 12 215-224 (10 pages)

Haan, Jae-Hee, Cho, Soo-Wan, Yang, Young-Sun, Park, Young-Geun, Park, Hong-Gi, Chang, Gyeong-Jae, Kim, Yang-Mi, Park, Choon-Ok, Hong, Se 저
...
- 3,000원
reached its maximum within 20ms beyond -3OmV and decayed rapidly with an inactivation time constant τ of 15ms. Activation and inactivation of this iCa2+ was steeply dependent on the membrane potential. The iCa2+ began to activate at the lower voltage of -55 mV and reached its peak at -35 mV, being completely inactivated at potentials more positive than -40 mV. These result suggest that iCa2+ in hamster eggs passes through channels with electrical properties similar to low voltage-activated...
497.

Effects of cGMP on the Contractility and Ca Movement in the Aorta of Normotensive Wistar-Kyoto Rats and Spontaneously Hypertensive Rats

Park, Hae-Kun, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Chang, Seok-Jong 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 8 181-190 (10 pages)

Park, Hae-Kun, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Chang, Seok-Jong 저
...
- 3,000원
Endothelium-derived relaxing factor (EDRF) activates guanylate cyclase which mediates the formation of cGMP from GTP in vascular smooth muscle. It is well known that endothelium-dependent relaxation is impaired in spontaneously hypertensive rats (SHR). However, it is still unknown whether the impaired endothelium-dependent relaxation in SHR results from the reduced release of EDRF or from the decrease of vascular response to EDRF. We investigated the effects of cGMP on the contractility and Ca...
498.

Effect of pH on the Vascular Tone and 45Ca Uptake in the Aorta of Spontaneously Hypertensive Rats

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Park, Hae-Kun 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 7 169-180 (12 pages)

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Park, Hae-Kun 저
...
- 4,100원
The effect of extracellular and intracellular pH on vascular tone and 45Ca uptake were investigated in aortic strips and dispersed single aortic smooth muscle cells of spontaneously hypertensive rats (SHR) and aged-matched Wistar-Kyoto rats (WKY). The contraction produced by a change of extracellular pH (pHo) in the range of 6.5 ~ 8.3 was estimated by comparison with the level of vascular tone at pH 7.4. Contraction was induced below pHo 6.5 in WKY, pHo 7.1 in SHR, and over pHo 8.0 on both...
499.

Calcium-activated Ionic Currents in Smooth Muscle Cells from Rabbit Superior Mesenteric Artery

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 5 151-158 (8 pages)

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 저
...
- 3,000원
Cs+. A Ca2+-activated nonselective cation current was observed in both the depolarized and hyperpolarized potential ranges. And it was blocked by replacement of extracellular Na+ with N-methylglucamine (NMG) or extracellular application of Cd2+. Ca2+-activated Cl- current was revealed in the whole voltage range and was blocked by niflumic acid. These results indicate that at least three kinds of Ca2+-activated ionic currents exist in smooth muscle cells from rabbit superior mesenteric artery.
500.

Ca2+-activated Cl- Current in Gastric Antral Myocytes

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 4 143-150 (8 pages)

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 저
...
- 3,000원
to isolate the chloride current from background current, all known systems were blocked with specific blockers. The current-voltage relationship of caffeine-induced current showed outward rectification and it reversed at around ECl-. The shift of reversal potential upon the alteration of external and internal chloride concentrations was well fitted with results which were calculated by the Nernst equation. Extracellular addition of N-phenylanthranilic acid and niflumic acid which are known anion...

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