자료유형
발행기관
- 대한수의학회(412)
- 대한생리학회-대한약리학회(131)
- 한국식물병리학회(115)
- 한국미생물생명공학회(36)
- 한국생물공학회(18)
- 대한신경정신의학회(15)
- 대한약리학회(7)
- 대한치과이식임플란트학회(7)
- 한국생명과학회(7)
- 한국미생물학회(6)
- 한국기초간호학회(3)
- 생화학분자생물학회(2)
- 한국보건기초의학회(2)
- 한국식품과학회(2)
- 한국웰니스학회(2)
- 한국환경독성학회(2)
- 대한기생충학회(1)
- 대한동의생리학회(1)
- 대한면역학회(1)
- 대한생리학회(1)
- 대한치과교정학회(1)
- 대한치주과학회(1)
- 대한환경공학회(1)
- 배재대학교 자연과학연구소(1)
- 영남의대학술지편집위원회(1)
- 인문사회과학기술융합학회(1)
- 한국가금학회(1)
- 한국분자세포생물학회(1)
- 한국습지학회(1)
- 한국식품영양과학회(1)
- 한국응용약물학회(1)
- 한국잠사학회(1)
- 한국조형교육학회(1)
- 한국탄소학회(1)
- 한국화학공학회(1)
- 한방비만학회(1)
간행물
- JOURNAL OF VETERINARY SCIENCE(200)
- 대한수의학회 학술대회발표집(134)
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(131)
- THE PLANT PATHOLOGY JOURNAL (100)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(78)
- JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY(28)
- 식물병연구(15)
- 신경정신의학(15)
- BIOTECHNOLOGY AND BIOPROCESS ENGINEERING(11)
- JOURNAL OF DENTAL IMPLANT RESEARCH(7)
- 대한약리학잡지(7)
- 생명과학회지(7)
- 한국생물공학회지(7)
- 한국미생물-생명공학회지(5)
- THE JOURNAL OF MICROBIOLOGY(4)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(3)
- 산업미생물학회지(3)
- JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY(2)
- 한국보건기초의학회지(2)
- 한국웰니스학회지(2)
- 환경독성학회지(2)
- BIOMOLECULES & THERAPEUTICS(1)
- CARBON LETTERS(1)
- FOOD SCIENCE AND BIOTECHNOLOGY(1)
- IMMUNE NETWORK : OFFICIAL JOURNAL OF THE KOREAN ASSOCIATION OF IMMUNOBIOLOGISTS(1)
- INTERNATIONAL JOURNAL OF INDUSTRIAL ENTOMOLOGY(1)
- JOURNAL OF FOOD SCIENCE AND NUTRITION(1)
- KOREAN CHEMICAL ENGINEERING RESEARCH(1)
- MOLECULES AND CELLS(1)
- THE KOREAN JOURNAL OF ORTHODONTICS(1)
- THE KOREAN JOURNAL OF PARASITOLOGY(1)
- 대한생리학회지(1)
- 대한치주과학회지(1)
- 대한한방비만학회지(1)
- 대한환경공학회지(1)
- 동의생리병리학회지(1)
- 미생물과 산업(1)
- 미생물학회지(1)
- 영남의대 학술지(1)
- 예술인문사회융합멀티미디어논문지(1)
- 자연 과학 논문집 : 배재대학 첨단과학연구소(1)
- 한국가금학회지(1)
- 한국습지학회지(1)
- 한국식품과학회지(1)
- 한국조형교육학회 학술대회지(1)
전체 선택해제
총 787건 검색
본문검색 결과만 보기
-
Effect of Amrinone, a Selective Inhibitor of Phosphodiesterase III, on PMNs-induced
ByungKwonOh, HyoungKiKim, SooRanChoi, JinHoSong, EonSubPark, Byung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 7 43-50 (8 pages)
Ischemia followed by reperfusion in the presence of polymorphonuclear leukocytes (PMNs) results in a marked cardiac contractile dysfunction. Amrinone, a specific inhibitor of phosphodiesterase 3, has an antioxidant activity against PMNs. Therefore, we hypothesized that amrinone could attenuate PMNs-induced cardiac dysfunction by suppression of reactive oxygen species (ROS) produced fby PMNs. In the present study, we examined the effects of amrinone on isolated ischemic (20 min) and reperfused... -
A Possible Role of Kainate Receptors in C2C12 Skeletal Myogenic Cells
Jae-YongPark, JaeheeHan, Seong-GeunHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 13 375-379 (5 pages)
Ca2 influx appears to be important for triggering myoblast fusion. It remains, however, unclear how Ca2 influx rises prior to myoblast fusion. Recently, several studies suggested that NMDA receptors may be involved in Ca2 mobilization of muscle, and that Ca2 influx is mediated by NMDA receptors in C2C12 myoblasts. Here, we report that other types of ionotropic glutamate receptors, non-NMDA receptors (AMPA and KA receptors), are also involved in Ca2 influx in... -
Carrageenan-Induced Hyperalgesia Is Partially Alleviated by Endomorphin-1 Locally Delivered into Inflamed Paws in Rat
SeoEunLeeHongKeeShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 12 369-373 (5 pages)
This study was performed to test whether endomorphin-1 has analgesic effect, when locally administrated into inflamed peripheral tissue. Carrageenan suspension (0.5%) was injected intraplantarly into the right paw of Sprague-Dawley male rats, and the rats were subjected to a series of mechanical stimuli with von Frei filaments before and after the injection. Carrageenan-injected rats showed typical inflammatory hyperalgesic signs and decrease of withdrawal threshold, peaked at 3 to 6 hours after... -
Prevention of Diabetes Using Adenoviral Mediated Hepatocyte Growth Factor Gene Transfer in Mice
Hye-JeongLee, Hyun-JeongKim, Mee-SookRoh, Jae-IkLee, Sung-WonLee, Dong-SikJung, Duk-KyuKim, Mi-KyoungPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.5 3 261-266 (6 pages)
Type 1 diabetes is an organ-specific autoimmune disease caused by the cytotoxic T cells-mediated destruction of the insulin-producing beta cells in the Langerhans pancreatic islets. Hepatocyte growth factor (HGF) is a potent mitogen and a promoter of proliferation of insulin producing beta cells of pancreatic islets. To study the role of HGF via viral vector in the development of streptozotocin (STZ)-induced diabetes in mice, we have developed an adenoviral vector genetically engineered to carry... -
Salicylate Regulates Cyclooxygenase-2 Expression through ERK and Subsequent NF-κB Activation in Osteoblasts
Han-JungChae, Jun-KiLee, Joung-OukByun, Soo-WanChae, Hyung-RyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 8 239-246 (8 pages)
MC3T3E1 osteoblasts. Furthermore, antioxidants such as catalase, N-acetyl-cysteine or reduced glutathione attenuated COX-2 expression in combined cytokines-treated cells, and also inhibited the activation of ERK, IKK and NF-κB in MC3T3E1 osteoblasts. In addition, TNF-α/IFN-γ stimulated ROS release in the osteoblasts. However, salicylate had no obvious effect on ROS release in DCFDA assay. The results showed that salicylate inhibited the activation of ERK and IKK, IκB degradation and NF-κB... -
PDTC Inhibits TNF-α-Induced Apoptosis in MC3T3E1 Cells
Han-JungChae, JeehyeonBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 2 199-205 (7 pages)
activation of nuclear factor (NF-κB), on the induction of TNF-α-induced activation of JNK/SAPK, AP-1, cytochrome c, caspase and apoptosis in MC3T3E1 osteoblasts. Pretreatment of the cells with PDTC blocked TNF-α-induced NF-κB activation. TNF-α-induced activation of AP-1, another nuclear transcription factor, was suppressed by PDTC. The activation of c-Jun N-terminal kinase, implicated in the regulation of AP-1, was also down regulated by PDTC. TNF-α-induced apoptosis, release of cytochrome... -
Alteration of Substrate Specificity by Common Variants, E158K/E308G and V257M, in Human Hepatic Drug-metabolizing Enzyme, Flavin-containing Monooxygenase 3
Jung-KyuLee, Ju-HeeKang, Young-NamCha, Woon-GyeChung, , Chang-ShinPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 6 157-162 (6 pages)
exon 4 (E158K) and exon 7 (E308G) of the FMO3 gene in Korean volunteers. However, caffeine N-1 demethylation (which is also partially catalyzed by FMO) was not significantly correlated with these FMO3 mutations. In this study, we examined another common mutation (V257M) in exon 6 of FMO3 gene. The V257M variant, which is caused by a point mutation (G769A), was commonly observed (13.21% allele frequency) in our subjects (n=159). This point mutation causes a substitution of Val257 to Met257, with... -
Inhibitory and Excitatory Postsynaptic Currents of Medial Vestibular Nucleus Neurons of Rats
SangWooChun, JeongHeeChoi, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 2 59-63 (5 pages)
The medial vestibular nucleus (MVN) neurons are controlled by excitatory synaptic transmission from the vestibular afferent and commissural projections, and by inhibitory transmission from interneurons. Spontaneous synaptic currents of MVN neurons were studied using whole cell patch clamp recording in slices prepared from 13- to 17-day-old rats. The spontaneous inhibitory postsynaptic currents (sIPSCs) were significantly reduced by the GABAA antagonist bicuculline (20μM), but were not affected... -
Overexpressed Mitochondrial Thioredoxin Protects PC12 Cells from Hydrogen Peroxide and Serum-deprivation
Yun-SongLee, Seung-AYu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.1 7 33-37 (5 pages)
Oxidative damage to mitochondria is a critical mechanism in necrotic or apoptotic cell death induced by many kinds of toxic chemicals. Thioredoxin (Trx) family proteins are known to play protective roles in organisms under oxidative stress through redox reaction by using reducing equivalents of cysteines at a conserved active site, Cys-X-X-Cys. Whereas biological and physiological properties of Trx1 are well characterized, significance of mitochondrial thioredoxin (Trx2) is not well known.... -
Blockade of p38 Mitogen-activated Protein Kinase Pathway Inhibits Interleukin-6 Release and Expression in Primary Neonatal Cardiomyocytes
Han-JungChae, Hyun-KiKim, Wan-KuLee, Soo-WanChae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.6 7 319-325 (7 pages)
The induction of interleukin-6 (IL-6) using combined proinflammatory agents (LPS/IFN-γ or TNF-α/ IFN-γ) was studied in relation to p38 mitogen-activated protein kinase (MAPK) and NF-κB transcriptional factor in primary neonatal cardiomyocytes. When added to cultures of cardiomyocytes, the combined agents (LPS/IFN-γ or TNF-α/IFN-γ) had stimulatory effect on the production of IL-6 and the elevation was significantly reduced by SB203580, a specific p38 MAPK inhibitor. SB203580 inhibited...
