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Calcium Current and Background Current Activation in L-triiodothyronine Loaded Ventricular Myocytes of the Rabbit
Han, Jin, Kim, Eui-Yong, Han, Jae-Hee, Park, Choon-Ok, Hong, Seong-Geun, Leem, Chae-Hun, So, In-Suk, Ho, Won-Kyung, Earm, Yung-E, Sung, H 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 2호 1 99-112 (14 pages)
Permissive action of thyroid hormone at the level of Ca channel and responsible mechanisms underlying thyroid hormone-induced change in myocardial contractile state and T3-induced arrhythmias were investigated in rabbit ventricular or atrial myocytes using whole cell patch clamp technique. Single cells were isolated by Langendorff perfusion with collagenase. Cardiac myocytes were incubated in low-Cl-,, high-K+ medium containing 1μM L-triiodothyronine (T3) at 4℃ for 2.10 hours. The calcium... -
Ionic Dependence and Modulatory Factors of the Background Current Activated by Isoprenaline in Rabbit Ventricular Cells
Leem, Chae-Hun, Lee, Suk-Ho, So, In-Suk, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 1호 2 15-26 (12 pages)
In order to elucidate the properties of the background current whole cell patch clamp studies were performed in rabbit ventricular cells. Ramp pulses of ±80 mV from holding potential of 40 mV(or 20 mV) at the speed of 0.8 V/sec were given every 30 sec(or 10 sec) and current-voltage diagrams(I-V curve) were obtained. For the activation of the background current isoprenaline, adenosine 3 ,5 -cyclic monophosphate(dBcAMP), guanosine 3 ,5 -cyclic monophosphate(cGMP), and N6-2 -o-dibutyryladenosine 3... -
Role of Rostroventrolateral Medulla in Somatosympathetic Pressor and Depressor Response Evoked by Peripheral Nerve Stimulation
Jun, Jae-Yeoul, Yeum, Cheol-Ho, Goo, Yong-Sook, Kim, Jun 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 2호 10 201-210 (10 pages)
The rostral ventrolateral medulla (RVLM) has been established recently as a sympathoexcitatory area. The present study was conducted to investigate whether the somatosympathetic pressor and/or depressor responses are mediated through RVLM in cats anesthetized with α-chloralose. An occipital craniectomy was performed and ventrolateral medulla were stimulated either electrically or chemically to evoke changes in arterial blood pressure. And then the effect of lesions in the ventrolateral medulla... -
A Study on Na+ and Water Reabsorption in the Nephron Segment Beyond Proximal Tubule Measured by Lithium Clearance
Han, O-Soo, Goo, Yong-Sook, Sung, Ho-Kyung 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 2호 9 189-200 (12 pages)
During the past few years it has been proposed that lithium clearance can be used as a reliable measure for the outflow of tubular fluid from the proximal tubule. This study was aimed to characterize the inflow dependent reabsorption of Na in renal tubule beyond the proximal tubule. For this purpose, lithium clearance was used as a measure for the inflow from the proximal tubule and the changes in reabsorption fraction of Na and water were determined in rabbits. Rabbits were pretreated with... -
The Contractile and Electrical Responses of Guinea-pig s Gastric Smooth Muscle to Serotonin
Lee, Sang-Jin, Hwang, Sang-Ik, Kim, Ki-Whan 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 2호 4 133-146 (14 pages)
In order to elucidate systematically the effects of serotonin on gastric motility of guinea-pig, the contractile and electrical responses to serotonin were recorded using four kinds of muscle strips prepared from antral circular, antral longitudinal, fundic circular, and fundic longitudinal muscles. Experiments were performed using various methods including isometric contraction recording, transmural electrical field stimulation, junction potential recording, intracellular microelectrode... -
Effect of Unilateral Pneumonectomy on the Secretory Function of Type II Pneumocyte and Compensatory Growing Pattern of the Residual Lung in Growing Rabbits
Lee, Young-Man, Lee, Suck-Kang, Choo, Young-Eun 대한생리학회 대한생리학회지 6 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 1호 8 81-86 (6 pages)
significantly. Phospholipid concentration in the lung lavage fluid of the pneumonectomized rabbits was over two times higher than that of control rabbits. from these experimental results, It is concluded that unilateral pneumonectomy in growing rabbits might cause to increase the secretion of pulmonary surfactant from type II pneumocyte of the residual lung. The cellular hyperplasia seems to be the primary response of the compensatory growing lung in unilateral pneumonectomized growing rabbits. -
Nephron Heterogeneity of Renin Release in Rat Kidney Slices: Effects of L-Isoproterenol, Angiotensin II and TMB-8
Seul, Kyung-Hwan, Kim, Suhn-Hee, Koh, Gou-Young, Cho, Kyung-Woo 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 1호 6 61-68 (8 pages)
In order to determine possible relationships between the renin-angiotensin system and nephron heterogeneity, we compared the response of renin release and the angiotensin-converting enzyme (ACE) activity from different areas of the rat kidney. We used the renal cortical slices from the capsular surface to the juxtamedullary junction. Slices from outer one-third of the cortex were designated as outer cortical slices (OC), middle one-third as midcortical slices (MC), and inner one-third as inner... -
Effect of Probenecid on Urate Excretion in the Cat Kidney
Jung, Dong-Keun, Kim, Yong-Keun, Jung, Jin-Sup, Lee, Sang-Ho 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 1호 4 37-48 (12 pages)
the rabbit, FEur} was 1.76±0.08 and net urate secretion was observed, while, in the cat FEur was 0.70±0.02 and net reabsorption was observed. In the cat FEur was dependent on urine flow and independent of plasma urate concentration. In the rabbit FEur was suppressed by infusion of probenecid (30 mg/kg -0.6 mg/kg·min) into femoral vein. In the cat the same dose of probenecid increased FEur and concomitantly increased urine flow. Thus, an increase in FEur by probenecid could be considered to be... -
Effect of pH on Calcium-Activated Potassium Channels in Pulmonary Arterial Smooth Muscle Cells of the Rabbit
Lee, Suk-Ho, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 1호 2 17-26 (10 pages)
Single smooth muscle cells of the rabbit pulmonary artery were isolated by treatment with collagenase and elastase. Using the patch clamp technique, potassium channel activity was recorded from the inside-out membrane patch. The channel had a sin히e channel conductance of about 360 pS in symmetrical concentration of K on both sides of the patch, 150 mM, and had a linear current-voltage relationship. During the application of 10 mM tetraethylammonium (TEA) to the intracellular membrane surface,... -
한국산 무당개구리 피부에 존재하는 Bombesin 유사면역 반응물질의 순수정제 및 생물학적 활성
권혁일(Kwon, Hyeok-Yil), 김일(Kim, Yil), 박형진(Park, Hyoung-Jin) 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1990, 제 24권 제 2호 11 363-376 (14 pages)


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