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Adenosine Agonist-induced Changes in the Transmission of Sensory Signals in the Cat Spinal Cord
Kim, Kee-Soon, Shin, Hong-Kee, Kim, Jin-Hyuk 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 9 85-96 (12 pages)
the anesthetized cat. All the tested adenosine agonists(i.v,) exerted inhibitory effects on the responsiveness of the wide dynamic range (WDR) cells, the inhibitory action of CHA, an adenosine A1 receptor agonist, (80μg/Kg) being most weak. The intravenous CPCA, an adenosine A2 receptor agonist, (20μg /Kg) and NECA, nonspecific adenosine receptor agonist, (20μg /Kg) inhibited the responses of WDR cells to pinch and C fiber stimulation more strongly than those to brush and A fiber stimulation.... -
Effects of Morphine on Somatosyrnpathetic Reflex and Arterial Blood Pressure Response Evoked by Stimulation of Peripheral Nerves
Huh, Min-Gang, Yan, Hai-Dun, Lim, Won-Il, Kim, Jun 대한생리학회 대한생리학회지 13 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 13 309-321 (13 pages)
cardiac-related rhythm. However, most of the muscular sympathetic fibers had cardiac-related rhythm and only four fibers showed respiratory rhythm. 4) Morphine decreased the sympathetic C-reflex elicited by the peripheral C-afferent activation and the abdominal sympathetic A-reflex was also decreased by morphine. From the above results, it was concluded that supraspinal mechanisms were involved in the enhanced arterial pressor response to peripheral C-afferent activation by intravenous morphine. -
Effect of Blood Pressure on Contractility of Vascular Smooth Muscle and Endothelium-Dependent Relaxation
Suh, Suk-Hyo, Park, Yee-Tae, Lee, Dong-Chul, Seo, Pil-Won, Kim, Ki-Whan 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 10 279-290 (12 pages)
This study was designed 1) to develop a hypertensive animal model in which the blood pressures (BPs) of symmetric regions (right and left upper extremities) are significantly different and 2) to test the effect of BP per se on the contractility and endothelium-dependent relaxation of vascular smooth muscle. Rabbits were anesthetized with sodium pentobarbital and ventilated with room air via animal respirator. The transverse aorta was exposed through the left second intercostal space and the... -
Enhanced Expression of Angiotensinogen mRNA in Rat Central and Peripheral Tissues Following Hemorrhage
Do, Eun-Ju, Yang, Eun-Kyoung, Kim, Kyung-Soon, Kim, Suk-Hee, Park, Yoon-Yub, Ahn, Dong-Kuk, Park, Jae-Sik, Lee, Won-Jung 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 8 259-268 (10 pages)
The renin-angiotensin system plays an important role in the regulation of blood pressure and in body fluid homeostasis. There is increasing evidence for generation of endogenous angiotensin II in many organs and for its role in paracrine functions. Studies were designed to investigate whether hemorrhage produces rapid changes in the gene expression of angiotensinogen in peripheral and brain tissues. Wistar rats received saline drinking water for 7 days, were bled at a rate of 3mlkg-1 min-1 for... -
Effects of Ethanol on Neurohumoral Mechanisms for Blood Pressure Regulation in Hemorrhaged Conscious Rats
Park, Yoon-Yub, Park, Jae-Sik, Lee, Won-Jung 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 1호 9 91-102 (12 pages)
The effects of prolactin and vasopressin on the regulation of amniotic fluid (AF) volume and its Na+ concentration Na+ through the membrane surrounding the AF during increase in AF volume due to fetal urination were studied. About 70% of AF volume was replaced with normal isotonic saline solution. Isotonic saline solution (0.5 ml) containing Censored and LiCl was introduced into each amniotic sac. Vasopressin (25 ng/ml) or prolactin (1 mg/ml) of AF was then injected into experimental amniotic... -
Effect of Preconditioning Ischemia on Endothelial Dysfunction Produced by Ischemia-Reperfusion in Rabbit Coronary Artery
Suh, Suk-Hyo, Park, Yee-Tae, Kim, Woong-Heum, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 1호 5 51-60 (10 pages)
This study was designed to test whether or not 1) ischemia-reperfusion attenuates endothelium-dependent relaxation of coronary arteries and 2) preconditioning protects the arterial endothelium from ischemia-reperfusion injury. In anesthetized open chest rabbits, branches of the left circumflex artery were exposed to different combinations of the experimental conditions; ischemia (15 minutes), ischemia (15 minutes)-reperfusion (10 minutes), preconditioning ischemia, and pre-conditioning fellowed... -
Inhibitory Effects of Verapamil and TMB-8 on Tonic Contraction Are Accompanied by Inhibition of Phospholipase C Activity in Intact Gastric Smooth Muscle Cells
Sim, Sang-Soo, Yoon, Shin-Hee, Hahn, Sang-June, Rhie, Duck-Joo, Jo, Yang-Hyeok, Kim, Myung-Suk 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 1호 3 29-38 (10 pages)
Gastric smooth muscle of guinea pigs was used to investigate whether the inhibitory effect of calcium antagonists on tonic contraction was accompanied by inhibition of phospholipase C activity. Tonic contraction and [3H] inositol phosphate (IP) formation in response to acetylcholine were measured after pretreatment with verapamil, nifedipine, 8-(N,N-diethylamino)octyl 3,4,5-trimethoxy-benzoate (TMB-8) or EGTA. Verapamil (10 μM), TMB-8 (10 μM) or EGTA (2 mM) significantly inhibited... -
Role of Endogenous Nitric Oxide in the Control of Renin Release
Lee, Je-Jung, Kim, Dong-Ho, Kim, Young-Jae, Kim, Won-Jae, Yoo, Kwang-Jay, Choi, Ki-Chul, Lee, Jong-Eun, 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 13 225-232 (8 pages)
in the rat. VE was induced by intravenous infusion of saline (0.9% NaCl) up to 5% of the body weight over 45 min under thiopental (50 mg/kg, IP) anesthesia. VE caused a decrease of plasma renin concentration (PRC). With NG-nitro-L-arginine methyl ester (L-NAME, 5 μg/kg per min) superadded to VE, PRC decreased further. The magnitude of increase in plasma atrial natriuretic peptide levels following VE was not affected by the L-NAME. In two-kidney, one clip rats, L-NAME-supplementation resulted in... -
A Central Pressor Response to Endogenous Nitric Oxide Synthesis Inhibition in Anesthetized Rats
Moon, Sung-Ho, Yang, Min-Joon, Oh, Seung-Ho, Kim, Mi-Won, Yoo, Kwang-Jay, Lee, Jong-Eun, Jun, Jae-Yeoul, Yeum, Cheol-Ho, Yoon, Pyung-Jin 대한생리학회 대한생리학회지 6 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 10 197-202 (6 pages)
and heart rate. Plasma renin concentrations(PRC) were significantly lower in L-NAME-infused group than in the control. L-Arginine (60 μg/min, ICV) prevented the pressor response to ICV L-NAME. The pressor response was not affected by simultaneous intravenous infusion of saralasin, but was abolished by hexamethonium treatment. Intravenous infusion (40 μL/min, 10 ~ 100 μg/kg per minute for 60 min) also increased blood pressure, while it decreased heart rate. These results indicate that endogeno... -
Conduction Block of the Primary Afferent Fibers by Topically Applied Allyl Isotheocyanate
Shin, Hong-Kee, Kim, Kee-Soon, 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 2 123-132 (10 pages)
The present study was undertaken to elucidate the desensitization of cutaneous receptors and the conduction block of the afferent nerves induced by direct application of allyl isotheocyanate (mustard oil) to the receptive field (RF) or onto the afferent nerve, respectively. Dorsal horn cell responses to mechanical stimulations of RF were completely suppressed when mustard oil was applied to either the afferent nerve or the whole area of RF. C-fiber responses of dorsal horn cells were more...


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