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전체 선택해제
총 292건 검색
본문검색 결과만 보기
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Effects of Calcium Channel Blockers on Porcine Cardiac and Coronary Arterial Function in Ischemia-Reperfusion
YungHongBaik, HyunKook, SunHeePark, SeongJooJeong, DongYoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 7 587-595 (9 pages)
This study was designed to investigate effects of calcium antagonists on endothelial and neuronal dysfunction of right coronary artery (RCA) induced by ischemia- reperfusion in anesthetized, open-chest pigs. After reperfusion, pigs were sacrificed and the RCA was rapidly dissected for in vitro experiments. Experimental groups were divided into 4 groups: control (C-RCA), ischemia-reperfusion only (I-RCA), verapamil infusion (VI-RCA) and nifedipine infusion (NI-RCA) group, respectively. The... -
Protective Mechanism of Nitric Oxide and Mucus against Ischemia/ Reperfusion-Induced Gastric Mucosal Injury
HyeyoungKim, KwangsooNam, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 13 511-519 (9 pages)
This study investigated the role of nitric oxide on the oxidative damage in gastric mucosa of rats which received ischemia/reperfusion and its relation to mucus. Nitric oxide synthesis modulators such as L-arginine and NG-nitro-L-arginine methyl ester, and sodium nitroprusside, a nitric oxide donor, were injected intraperitoneally to the rats 30 min prior to ischemia/reperfusion which was induced by clamping the celiac artery and the superior mesenteric artery for 30 min and reperfusion for 1... -
Inhibitory Effect of Caffeine on Carbachol-Induced Nonselective Cationic Current in Guinea-Pig Gastric Myocytes
SungJoonKim, KyungWanMin, YoungChulKim, SangJinLee, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 10 353-359 (7 pages)
In gastrointestinal smooth muscle, muscarinic stimulation by carbachol (CCh) activates nonselective cation channel current (ICCh) which is facilitated by intracellular [Ca2] increase. Caffeine is widely used in experiments to mobilize Ca2 from intracellular stores. This study shows a strong inhibitory effect of caffeine on ICCh in guinea-pig gastric myocyte. In this study, the underlying mechanism of the inhibitory effect of caffeine was investigated. ICCh was completely... -
Regulatory Mechanisms of Angiotensin II on the Na+/H+ Antiport System in Rabbit Renal Proximal Tubule Cells. II. Inhibitory Effects of ANG II on Na+ Uptake
HoJaeHan, SooHyunPark, HyunJuKoh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 9 425-434 (10 pages)
Many reports represent that angiotensin II (ANG II) caused a dose dependent biphasic effects on fluid transport in the proximal tubule. However, respective roles of different signaling pathways in mediating these effects remain unsettled. The aim of the present study was to examine signaling pathways at high doses of ANG II on the Na+ uptake of primary cultured rabbit renal proximal tubule cells(PTCs) in hormonally defined serum-free medium. High concentrations of ANG II (＞10-9 M) inhibited... -
신경병증성 통증 모델 쥐에서 뇌간 핵의 전기자극이 후각세포의 기계자극에 대한 반응도에 미치는 영향 Effects of Electrical Stimulation of Brainstem Nuclei on Dorsal Horn Neuron Responses to Mechanical Stimuli in a Rat Model of Neuropathic Pain
임중우, 최윤, 곽영섭, 남택상, 백광세, JoongWooLeem, YoonChoi, YoungSeobGwak, TaikSangNam, KwangSePaik 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 3 241-249 (9 pages)
The aim of the present study is to examine the brainstem sites where the electrical stimulation produces a suppression of dorsal horn neuron responses of neuropathic rats. An experimental neuropathy was induced by a unilateral ligation of L5-L6 spinal nerves of rats. Ten to 15 days after surgery, the spinal cord was exposed and single-unit recording was made on wide dynamic range (WDR) neurons in the dorsal horn. Neuronal responses to mechanical stimuli applied to somatic receptive fields were... -
초발 정신분열병 환자에서 자기공명영상을 이용한 뇌용적 분석
신상은, 강민희, 이정섭, 김철응, 배재남, 최성욱 대한신경정신의학회 신경정신의학 16 Pages
대한신경정신의학회 신경정신의학 2002, 제 41권 제 5호 12 847-862 (16 pages)
연구목적： 항정신병 약물을 사용하지 않은 초발 정신분열병 환자들을 대상으로 대뇌와 소뇌의 용적을 측정하 여 초기 정신분열병 환자의 뇌의 형태학적 특성을 분석하여 정신분열병의 구조적 병인을 정립할수 있 는 자료를 제공하도록한다. 방 법： 총 25명의 정신분열병 환자(평균 연령：31.20±7.85세, 연령의 범위：18~44세)와 29명의 정상 대조군(평균 연령：29.03±7.02세, 연령의 범위：18~42세)을 대상으로 용적의 분할을 시행하였다. 대 뇌와 소뇌를 회색질, 백색질 및 뇌척수액을 확률적인(probabilistic) 조직의...
