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Functional Characteristics of Lumbar Spinal Neurons Projecting to Midbrain Area in Rats
Park, Sah-Hoon, Kim, Geon 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 1 113-122 (10 pages)
The present study was carried out to characterize the functional properties of spinomesencephalic tract (SMT) neurons in the lumbar spinal cord of urethane anesthetized rats. Extracellular single unit recordings were made from neurons antidromically activated by stimulation of the midbrain area, including the deep layers of superior colliculus, periaqueductal gray and midbrain reticular formation. Recording sites were located in laminae I-VII of spinal cord segments of L2-L5. Receptive field... -
Effects of Centrally Administered Angiotensin ll Receptor Antagonists on the Cardiovascular and Hormonal Responses to Hemorrhage in Conscious SHR
Seo, Il-Sook, Yang, Eun-Kyoung, Park, Jae-Sik, Kim, Hyeong-Jin, Lee, Won-Jung 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 2호 10 217-226 (10 pages)
The role of endogenous brain angiotensin ll (Ang ll) in mediating the cardiovascular and vasopressin responses to hemorrhage was assessed in conscious spontaneously hypertensive rats (SHR), and normotensive Wistar-Kyoto (WKY) rats. Artificial cerebrospinal fluid (aCSF) with or without losartan (DuP 753), a specific Ang ll receptor subtype I (AT1) antagonist and saralasin, a combined AT1/AT2 antagonist was administered into the cerebral lateral ventricle. Hemorrhage was performed at a rate of 3... -
Cardiovascular Neurons Mediating Somatosympathetic Reflex in Rostral Ventrolateral Medulla
Goo, Yong-Sook, Kim, Sang-Jeong, Kim, Jun, Sung, Ho-Kyung 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 2호 7 185-198 (14 pages)
The rostral ventrolateral medulla (RVLM) includes vasopressor neurons, which transmit activation signals to the intermediolateral nucleus (IML) of the spinal cord, where the preganglionic sympathetic nucleus is located, to raise arterial blood pressure (BP). However, controversy exists as to the possible depressor area in the RVLM and the pathway involved. The present study persued evidence far the location of depressor neurons and the pathway by simultaneously observing changes in BP and the... -
Both Nifedipine and Bay K 8644 Potentiate the Release of Atrial Natriuretic Peptide in Response to Volume Expansion
Lee, Jong-Eun, Koh, Cheon-Suk, Yeum, Cheol-Ho 대한생리학회 대한생리학회지 6 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 5 51-56 (6 pages)
The effects of a calcium channel blocker and an activator on the release of atrial natriuretic peptide (ANP) were investigated in rats. They were volume expanded (VE) up to 5% of the body weight over 30min by being infused with iso-oncotic saline. Following VE, plasma ANP concentration markedly increased in association with increases in the right atrial pressure. Addition of either nifedipine (0.4μm/min) or Bay K 8644 (0.4μm/min) in the infusate potentiated the VE-induced release, although... -
Ventilatory Responses to Continuous Negative Pressure Breathing(CNPB) in Awake Dogs
Cha, Eun-Jong, Goo, Yong-Sook 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 4 37-50 (14 pages)
Ventilatory responses to inhaled CO2 were measured during continuous negative pressure breathing (CNPB) in awake dogs. End expiratory lung volume (EELV) decreased linearly with pressure level during CNPB (correlation coefficient= 0.81, p<0.005) during air breathing. When CNPB was applied during 5% CO2 inhalation, the decrease in EELV was not significantly different (p<0.5) from that during air breathing. As a result of a lowered EELV, tidal volume (VT) significantly decreased by 22% and... -
Effect of Changing Amniotic Fluid Osmolarity on the Li+ Transport Through the Membrane Surrounding Amniotic Fluid in the Rabbit
Chang, Jin-Keun, Lee, Sang-Jin, Sung, Ho-Kyung 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 2 13-26 (14 pages)
To study the regulation of amniotic fluid volume and electrolyte concentration by the Membranes surrounding the amniotic fluid, the rate of Li+ disappearance from amniotic sac of expired fetuses were examined while increasing the amniotic volume and osmolarity in rabbits. After intraamniotic injection of 1 ml isosmotic saline (about 20% of the amniotic fluid volume) containing 15 mM LiCl and 0.5 g/L Censored, the time courses of Li+ and Censored disappearance were determined. From there the Li+... -
A Novel Therapeutic Measure for Metabolic Acidosis with Amino Acids
Kim, Jun, Goo, Yong-Sook, Kim, Sang-Jeong, Park, Sang-Chul, Koh, Chang-Soon 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 1호 9 89-98 (10 pages)
In hypoxic tissue conditions, pyruvate can not enter the Krebs cycle and lactic acid, produced from pyruvate, accumulates to induce lactic acidosis. Pyruvate, However, can also be converted to alanine by glutamate pyruvate transaminase, that could be enhanced by glutamate. Therefore, it would be a fundamental measure to treat the lactic acidosis in tissue hypoxic conditions when one can convert the accumulated lactic acid, through pyruvate, to alanine. To test the above hypothesis, we induced a... -
Electrophysiological Study on Medullospinal Tract Cells Related to Somatosympathetic Reflex in the Cat
Kim, Sang-Jeong, Goo, Yong-Sook, Kim, Jun 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 1호 8 75-88 (14 pages)
It is well established that neurons in ventrolateral medulla play a key role in determining the vasomotor tone. The purpose of present study is to identify sympathetic related, medullospinal tract neurons in ventrolateral medulla and to show that these mediate somato-sympathetic reflex. Medullospinal tract cells were identified by antidromic stimulation to intermediolateral nucleus (IML) of the second thoracic (T2) spinal cord in anesthetized cats. Peripheral nerves were stimulated for... -
Central Pressor Mechanisms of Bradykinin in 2-Kidney, 1 Clip Goldblatt Hypertensive Rats
Yeum, Cheol-Ho, Jun, Jae-Yeoul, Yoon, Pyung-Jin 대한생리학회 대한생리학회지 6 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 1호 7 69-74 (6 pages)
Central cardiovascular effects of bradykinin were examined in anesthetized normotensive (NTR) and 2-kidney, 1 clip Goldblatt hypertensive rats (GHR). Bradykinin (0.5 ~ 10nmol) was administered into the right lateral cerebral ventricle, while blood pressure and heart rate (HR) were continuously monitored. In both NTR and GHR, intracerebroventricular bradykinin produced a dose dependent increase in mean arterial pressure (MAP) without significant changes in HR. GHR were more sensitive in the... -
The Electrophysiological Characteristics of Medullospinal Tract Cells in Cat Ventrolateral Medulla
Lee, Woo-Yong, Kim, Sang-Jung, Kim, Jun 대한생리학회 대한생리학회지 11 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 2호 11 211-221 (11 pages)
Although the existence of nerve cells which determine the activity of sympathetic nervous system in ventrolateral medulla is advocated recently, there are wide varieties on the location and function of them according to authors. Present study aimed to identify and characterize the medullospinal tract cells in rostral and caudal medulla of cats .which branch to the lateral horn of the upper thoracic spinal cord. Cats were anesthetized with α-chloralose. The upper thoracic spinal cord and floor...


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