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641.

Effects of Kanagawa Hemolysin on Blood Pressure and Arterial Tone in Rats

YoungMoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.4 8 225-233 (9 pages)

YoungMoonKim 저
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- 3,000원
of the same dose of KH induced a prominent depressor effect (iv KH-depressor effect). The icv KH-pressor effect was inhibited by acid-denaturation, while the iv KH-depressor effect was not. Simultaneous icv administration of the three agents (ouabain, diltiazem, or bumetanide: 10μg/kg each) significantly reduced the pressor effect. The icv KH-pressor effect was inhibited by treatment with iv phentolamine or chlorisondamine, but was not affected by iv candesartan. The iv KH-depressor effect was...
642.

Effect of Doxorubicin on Catecholamine Release in the Isolated Perfused Rat Adrenal Gland

Dong-YoonLim, Song-HoonOh, Yoo-SeungSeoh, Eun-SookLee, Il-HwanKim, Seong-HoJo, Soon-PyoHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.4 7 215-224 (10 pages)

Dong-YoonLim, Song-HoonOh, Yoo-SeungSeoh, Eun-SookLee, Il-HwanKim, Seong-HoJo, Soon-PyoHong 저
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- 3,000원
min produced relatively dose- and time-dependent inhibition of CA secretory responses evoked by ACh (5.32⁓10⁣3 M), DMPP (10⁣4 M) and McN-A-343 (10⁣4 M). However, lower dose of DX did not affect CA secretion by high K⁢ (5.6⁓10⁣2 M), but its higher doses depressed time-dependently CA secretion evoked by high K⁢. DX itself did also fail to affect basal CA output. In adrenal glands loaded with DX (3⁓10⁣7 M), CA secretory responses evoked by...
643.

Dual Effect of Dynorphin A on Single-Unit Spike Potentials in Rat Trigeminal Nucleus

KeunMiLee, HeeSeokHan, JaeHeeJang, DongKukAhn, JaeSikPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.3 3 213-221 (9 pages)

KeunMiLee, HeeSeokHan, JaeHeeJang, DongKukAhn, JaeSikPark 저
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- 3,000원
was infused into the amygdala, the number of NMDA-evoked spikes at the trigeminal nucleus decreased. However, the application of naloxone into the trigeminal nucleus while DAMGO being infused into the amygdala increased the number of spikes. Low dose (1 mM) of dynorphin in the trigeminal nucleus produced a significant decrease in NMDA-evoked spikes of the trigeminal nucleus but the NMDA-evoked responses were facilitated by a high dose (5 mM) of dynorphin. After the κ receptors were blocked with...
644.

Increased Response of Hypogastric Nerve Fibers to Bradykinin by Mustard Oil-Induced Uterine Inflammation in the Rat

ByeongKwonSeo, , JaeSungCho, MinGooLee, SeoEunLee, HeeChulHan, YoungWookYoon, SeungKilHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.1 14 99-105 (7 pages)

ByeongKwonSeo, , JaeSungCho, MinGooLee, SeoEunLee, HeeChulHan, YoungWookYoon, SeungKilHong 저
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- 3,000원
It is well known that the inflammation of somatic tissues, bladder and colon can alter the sensitivity of primary afferents innervating these tissues. To see if uterine afferents also show altered sensitivity, we examined their responses to the algesic agent bradykinin before and after induction of uterine inflammation. Inflammation was induced by injecting the mustard oil into the uterine lumen of adult female rats. After induction of inflammation, the response latency to bradykinin did not...
645.

GLUT Phosphorylation May be Required to GLUT Translocation Mechanism

Jong-SikHah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 8 487-496 (10 pages)

Jong-SikHah 저
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- 3,000원
In this work, GLUTs phosphorylations by a downstream effector of PI3-kinase, PKC-ζ, were studied, and GLUT4 phosphorylation was compared with GLUT2 phosphorylation in relation to the translocation mechanism. Prior to phosphorylation experiment, PKC-ζ kinase activity was determined as 20.76⁑4.09 pmoles Pi/min/25 ng enzymes. GLUT4 was phosphorylated by PKC-ζ and the phosphorylation was increased on the vesicles immunoadsorpted from LDM and on GLUT4 immunoprecipitated from GLUT4-...
646.

Ritanserin, a 5HT2/1C Receptor Antagonist, Does Not Block Cocaine- Induced Behavioral Alterations and zif268 mRNA Expression in the Striatum of the Rats

EunSangChoeJongYeonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 3 355-359 (5 pages)

EunSangChoeJongYeonKim 저
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- 1,500원
Cocaine induces immediate early gene expression and behavioral changes by blocking dopamine transporters in the terminals of nigrostriatal neurons in the striatum. The pharmacological role of serotonin 2/1C (5HT2/1C) receptors in cocaine-induced expression of zif268 (NGFI-A, egr1 and Krox-24) mRNA, a member of the zinc finger, was investigated using quantitative in situ hybridization histochemistry in vivo. Behavioral alterations induced by cocaine were also monitored in relation with blockade...
647.

Changes of the Level of G Protein α-subunit mRNA by Withdrawal from Morphine and Butorphanol

SeikwanOh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.4 4 291-299 (9 pages)

SeikwanOh 저
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- 3,000원
Morphine or butorphanol was continuously infused into cerebroventricle (i.c.v.) with the rate of 26 nmol/ μl/h for 3 days, and the withdrawal from opioid was rendered 7 hrs after the stopping of infusion. The expression of physical dependence produced by these opioids was evaluated by measuring the naloxone- precipitated withdrawal signs. The withdrawal signs produced in animals dependent on butorphanol (kappa opioid receptor agonist) were similar to those of morphine (mu opioid receptor...
648.

Effect of Atrial Natriuretic Peptide on the Proliferation and Activity of Osteoblastic Cells

Jong-RyeulLee, Seon-YleKo, Jung-KeunKim, Se-WonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.4 3 283-289 (7 pages)

Jong-RyeulLee, Seon-YleKo, Jung-KeunKim, Se-WonKim 저
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- 3,000원
natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). The present study was performed to investigate the effect of ANP on the proliferation and activity of ROS17/2.8 and HOS cells which are well-characterized osteoblastic cell lines. ANP dose-dependently decreased the number of ROS17/2.8 and HOS cells after 48-hour treatment. ANP generally increased the alkaline phosphatase activity of ROS17/2.8 and HOS cells after 48 hr treatment, regardless of the fact that basal activity of alkali...
649.

Effects of Cholecystokinin Octapeptide on Neuronal Activities in the Rat Nucleus Tractus Solitarius

HyewhonRhim, Chan-WoongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.4 2 275-281 (7 pages)

HyewhonRhim, Chan-WoongPark 저
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- 3,000원
by action potential firing. This CCK-evoked excitation was dose-dependent (10 nM∼10μM) and observed in more than 60% of NTS neurons. Under voltage clamp conditions, CCK-8S induced an inward current with a notably increased spontaneous excitatory synaptic activity. However, CCK-8S did not significantly change the amplitude of pharmacologically isolated and evoked EPSP(C)s. Using selective CCKA and CCKB receptor antagonists, we observed two different effects of CCK-8S, which suggest CCKA...
650.

Expression of Natriuretic Peptide mRNAs in Isoproterenol-Induced Cardiac Hypertrophy in Rats

Soo-kyungKim, Gee-younKwon, Eun-sookChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 8 235-241 (7 pages)

Soo-kyungKim, Gee-younKwon, Eun-sookChang 저
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- 3,000원
We examined the expression of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) mRNAs upon isoproterenol (Iso)-induced cardiac hypertrophy in rats. Then, we tried to investigate the effects of sympatholytics to see if they can modulate the expression of ANP and BNP. In this study, RT-PCR technique was used to characterize the expression of ANP and BNP in right atrium (RA) and left ventricle (LV) of the hypertrophied rat heart. Histologic findings indicated that stimulation of...

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