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681.

Effects of In Vitro Exposure to Silica on Bioactive Mediator Release by Alveolar Macrophages

Lee, Ji-Hee 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 1 1-12 (12 pages)

Lee, Ji-Hee 저
...
- 4,100원
Alveolar macrophages play a pivotal role in the pathogenesis of silicosis since the macrophages may release a wide variety of toxic and inflammatory mediators as well as mitogenic growth factors. In the present study, the effects of in vitro exposure to silica on release of various mediator such as reactive oxygen species, platelet activating factor(PAF), and interleukin-1 (IL-1) by alveolar macrophages were examined. First, hydrogen peroxide release from alveolar macrophages was monitored by...
682.

Role of Endogenous Nitric Oxide in the Control of Renin Release

Lee, Je-Jung, Kim, Dong-Ho, Kim, Young-Jae, Kim, Won-Jae, Yoo, Kwang-Jay, Choi, Ki-Chul, Lee, Jong-Eun, 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 13 225-232 (8 pages)

Lee, Je-Jung, Kim, Dong-Ho, Kim, Young-Jae, Kim, Won-Jae, Yoo, Kwang-Jay, Choi, Ki-Chul, Lee, Jong-Eun, 저
...
- 3,000원
The present study was undertaken to investigate the role of endogenous nitric oxide in renin release under different physiological conditions. In the first series of experiments, renin release was either inhibited by acute volume-expansion (VE) or stimulated by clipping one renal artery in the rat. VE was induced by intravenous infusion of saline (0.9% NaCl) up to 5% of the body weight over 45 min under thiopental (50 mg/kg, IP) anesthesia. VE caused a decrease of plasma renin concentration...
683.

Effects of cGMP on the Contractility and Ca Movement in the Aorta of Normotensive Wistar-Kyoto Rats and Spontaneously Hypertensive Rats

Park, Hae-Kun, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Chang, Seok-Jong 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 8 181-190 (10 pages)

Park, Hae-Kun, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Chang, Seok-Jong 저
...
- 3,000원
a cell membrane-permeable derivative of cGMP relaxed the 40 mM K+-induced contraction in a dose-dependent manner (10-6 ~ 10-4 M) in the endothelium-rubbed aortic strips of both strains. Also norepinephrine (10-6 M)-induced contractions in normal and Ca-free Tyrode s solution were suppressed by the pretreatment with 8-Br-cGMP (10-4 M) in either strain. However, the amplitudes of suppression induced by 8-Br-cGMP were greater in SHR than that in WKY. Basal 45Ca uptake and 40mM K+-stimulated 45Ca...
684.

Effect of pH on the Vascular Tone and 45Ca Uptake in the Aorta of Spontaneously Hypertensive Rats

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Park, Hae-Kun 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 7 169-180 (12 pages)

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Park, Hae-Kun 저
...
- 4,100원
The effect of extracellular and intracellular pH on vascular tone and 45Ca uptake were investigated in aortic strips and dispersed single aortic smooth muscle cells of spontaneously hypertensive rats (SHR) and aged-matched Wistar-Kyoto rats (WKY). The contraction produced by a change of extracellular pH (pHo) in the range of 6.5 ~ 8.3 was estimated by comparison with the level of vascular tone at pH 7.4. Contraction was induced below pHo 6.5 in WKY, pHo 7.1 in SHR, and over pHo 8.0 on both...
685.

Calcium-activated Ionic Currents in Smooth Muscle Cells from Rabbit Superior Mesenteric Artery

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 5 151-158 (8 pages)

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 저
...
- 3,000원
Intracellular free Ca2+ contributes to regulation of various events occurring in vascular smooth muscle cells. One of these events is modulating the membrane iou currents. Single smooth muscle cells were isolated from rabbit mesenteric artery. Three kinds of Ca2+-activated current were studied with the patch clamp method. Ca2+-activated K+ current with a large oscillation was recorded in the depolarized potential range. The single channel conductance of this current was about 250 pS. It was...
686.

Effects of Lemakalim, a Potassium Channel Opener, on the Contractility and Electrical Activity of the Antral Circular Muscle in Guinea-Pig Stomach

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 4 37-50 (14 pages)

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 저
...
- 4,300원
cell, KATP was suggested to be the channel responsible. However, there also are many results in favor of other types of K-channel $(maxi-K, small conductance KCa SKATP) mediating the effects of KCOs. Effects of lemakalim, (-)enantiomer of cromakalim (BRL 34915), on the spontaneous contractions and slow waves, were investigated in the antral circular muscle of the guinea-pig stomach. Membrane currents and the effects on membrane currents and single channel activities were also measured in single...
687.

Ca-dependent Alteration in Basal Tone, Basal 45Ca Uptake and 3H-nitrendipine Binding in the Aorta of Spontaneously Hypertensive Rats

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Hoe-Suk 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 3 27-36 (10 pages)

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Hoe-Suk 저
...
- 3,000원
2 mM Ca. The basal tone of aorta in SHR was suppressed by verapamil (10-6M). The basal tone of aorta in SHR increased about 50% in the strips of endothelial rubbing, compared with that of intact endothelium. Basal 45Ca uptake in the aortic single smooth muscle cells of SHR was greater than that of WKY (p<0.01), Specific bindings of [3H]nitrendipine in the aortic single smooth muscles of SHR and WKY were saturable. The dissociation constant (Kd) was 0.71±0.15 and 1.18±0.08nM SHR, respectively,...
688.

Role of Na+-K+ Pump on Endothelium-dependent Relaxation

Sung, Sang-Hyun, Roh, Joon-Ryang, Park, Tae-Sic, Suh, Suk-Hyo, Hwang, Sang-Ik, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 8 199-208 (10 pages)

Sung, Sang-Hyun, Roh, Joon-Ryang, Park, Tae-Sic, Suh, Suk-Hyo, Hwang, Sang-Ik, Kim, Ki-Whan 저
...
- 3,000원
the Na+ -K+ pump in the test strips. The magnitude of relaxation of test strip which was induced by the perfusate that had passed through the EDRF donor strip was decreased with the blockade of the Na+ -K+ pump in the test strip. Therefore, it could be suggested that the attenuation of endothelium-dependent relaxation caused by inhibiting Na+ -K+ pump activity is due to both the decreased release of EDRF from endothelial cells and the decreased sensitivity of the smooth muscle cells to EDRF.
689.

Effect of Dopamine on the Ca2+-dependent K+ currents in Isolated Single Gastric Myocytes of the Guinea-pig

Rhee, Poong-Lyul, Lee, Sang-Jin, Kim, Sung-Joon, So, In-Suk, Hwang, Sang-Ik, Kim, Ki-Whan 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 3 139-150 (12 pages)

Rhee, Poong-Lyul, Lee, Sang-Jin, Kim, Sung-Joon, So, In-Suk, Hwang, Sang-Ik, Kim, Ki-Whan 저
...
- 4,100원
of dopamine on the gastric smooth muscle, the effects of dopamine on voltage-dependent Ca2+ currents and Ca2+ -dependent K+ currents were observed in enzymatically dispersed guinea-pig gastric myocytes using the whole-cell voltage-clamp technique. Experiments were also done using isometric tension recording and conventional intracellular microelectrode techniques. 1) The effect of dopamine on the spontaneous contraction of antral circular muscle strips of the guinea-pig was excitatory in a...
690.

Role of Endogenous Nitric Oxide in the Vasorelaxation Induced by High Calcium Environment in vitro

Lee, Jong-Eun, Lee, Byung-Kook, Ahn, Hyun-Taek, Ahn, Byoung-Hee, Kang, Jung-Chaee 대한생리학회 대한생리학회지 6 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 2호 3 123-128 (6 pages)

Lee, Jong-Eun, Lee, Byung-Kook, Ahn, Hyun-Taek, Ahn, Byoung-Hee, Kang, Jung-Chaee 저
...
- 3,000원
The present study was undertaken to examine if endogenous nitric oxide is partly responsible for the high calcium induced vasorelaxation in vitro. Isolated porcine coronary arterial rings were suspended in the tissue chamber and their changes in isometric tension were recorded. KCI little affected the vascular tension in the calcium free media, but subsequent addition of cumulative doses of CaCl3 from 1 to 40 mM caused a contraction followed by complete relaxation. The maximum tension was noted...

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