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과개교합자의 저작근 활성도 및 교합력에 관한 연구
정동기(Dong-Ki Jeong), 김광원(Kwang-Won Kim) 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 1호 8 95-104 (10 pages)
본 연구의 목적은 T-Scan system과 근전도를 이용하여 정상교합자와 과개교합자의 최대교합력과 근활성도간의 상관관계를 조사하기 위함이다. 연구대상은 두 집단으로 구성되었다. 한 집단은 20명의 정상교합자이고 다른 집단은 30명의 과개교합자이다. 과개교합자는 Class I deepbite(9명의 남자와 7명의 여자)와 Class II div. 1 deepbite(8명의 남자와 6명의 여자)로 구성되었다. 이 연구로부터 얻어진 결과는 다음과 같다. 1. 최대교합력은 정상교합군에서 155.93N, I급 과개교합군에서 165.11 N, II급 1류 과개교합군에서... -
Activator 사용전후 부정교합 유형에 따른 각 근육 활성도의 변화에 관한 여구
이진우(Jin-Woo Lee), 차경석(Kyung-Suk Cha) 대한치과교정학회 The Korean Journal of Orthodontics 18 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 1호 6 65-82 (18 pages)
본 연구는 II급 및 III급 부정교합자를 대상으로 activator사용에 따른 각 근육의 적응 및 변화양상을 알아보고자 시행되었다. 본 연구의 대상은 성장 발육기에 있는 아동중 II급 부정교합자 15명과 III급 부정교합자 17명으로 기능적 요인을 갖고있는 자로 선정하였고, 연구방법은 전측두근(T.A.), 교근(M.M.), 후측두근(T.P.), 악이복근 전복(D.A.)의 활성도를 알아보고자 Biopak program과 쌍극표면전극을 이용하여 activator치료 시작시기와 사용후 6-12개월 사이의 두차례에 결쳐 안정위, 연하시, clenching등 세가지 조건에서... -
Inhibition of voltage-dependent K+ current in rabbit coronary arterial smooth muscle cells by the class Ic antiarrhythmic drug propafenone
Jin Ryeol An, Hongliang Li, Mi Seon Seo, Won Sun Park 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 13 597-605 (9 pages)
of the Kv current. Furthermore, the inactivation recovery time constant was increased after the application of propafenone, suggesting that the inhibitory action of propafenone on Kv current is partially use-dependent. Pretreatment with Kv1.5, Kv2.1 or Kv7 inhibitor did not change the inhibitory effect of propafenone on the Kv current. Together, these results suggest that propafenone inhibits the vascular Kv channels in a dose- and use-dependent manner, regardless of Na+ channel inhibition. -
Botulinum toxin type A enhances the inhibitory spontaneous postsynaptic currents on the substantia gelatinosa neurons of the subnucleus caudalis in immature mice
Seon-Hui Jang, Soo-Joung Park, Chang-Jin Lee, Dong-Kuk Ahn, Seong-Kyu Han 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 7 539-546 (8 pages)
Botulinum toxin type A (BoNT/A) has been used therapeutically for various conditions including dystonia, cerebral palsy, wrinkle, hyperhidrosis and pain control. The substantia gelatinosa (SG) neurons of the trigeminal subnucleus caudalis (Vc) receive orofacial nociceptive information from primary afferents and transmit the information to higher brain center. Although many studies have shown the analgesic effects of BoNT/A, the effects of BoNT/A at the central nervous system and the action... -
Conditioning-induced cardioprotection
Puneet Kaur Randhawa, Anjana Bali, Jasleen Kaur Virdi, Amteshwar Singh Jaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 1 467-479 (13 pages)
The aging process induces a plethora of changes in the body including alterations in hormonal regulation and metabolism in various organs including the heart. Aging is associated with marked increase in the vulnerability of the heart to ischemia-reperfusion injury. Furthermore, it significantly hampers the development of adaptive response to various forms of conditioning stimuli (pre/post/remote conditioning). Aging significantly impairs the activation of signaling pathways that mediate... -
Functional identification of protein phosphatase 1-binding consensus residues in NBCe1-B
KyuPilLee, HyunJinKim, DongkiYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 10 91-99 (9 pages)
Protein phosphatase 1 (PP1) is involved in various signal transduction mechanisms as an extensive regulator. The PP1 catalytic subunit (PP1c) recognizes and binds to PP1-binding consensus residues (FxxR/KxR/K) in NBCe1-B. Consequently, we focused on identifying the function of the PP1-binding consensus residue, 922FMDRLK927, in NBCe1-B. Using site-directed mutagenesis and co-immunoprecipitation assays, we revealed that in cases where the residues were substituted (F922A, R925A, and K927A) or... -
The bifunctional effect of propofol on thromboxane agonist (U46619)-induced vasoconstriction in isolated human pulmonary artery
NingHao, ZhaojunWang, SujuanKuang, GuangyanZhang, ChunyuDeng, JueMa, JianxiuCui 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 3 591-598 (8 pages)
Multi-Myograph system for measurement of isometric forces. U46619 was used to induce sustained contraction of the intrapulmonary arteries, and propofol was then applied (in increments from 10-300 μM). Arteries denuded of endothelium, preincubated or not with indomethacin, were used to investigate the effects of propofol on isolated arteries. Propofol exhibited a bifunctional effect on isolated human pulmonary arteries contracted by U46619, evoking constriction at low concentrations (10-100 μM)... -
Relaxant and anti-inflammatory effect of two thalidomide analogs as PDE-4 inhibitors in pregnant rat uterus
V?ctor Manuel Mu?oz-P?rez, Eduardo Fern?ndez-Mart?nez*, H?ctor Ponce-Monter, and Mario I. Ortiz 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.4 9 429-437 (9 pages)
The aim of this study was to evaluate the relaxant and anti-inflammatory effects of two thalidomide analogs as phosphodiesterase-4 (PDE-4) inhibitors in pregnant rat uterus. Uteri from Wistar female rats were isolated at 19 day of pregnancy. Uterine samples were used in functional studies to evaluate the inhibitory effects of the thalidomide analogs, methyl 3-(4-nitrophthalimido)-3-(3,4-dimethoxyphenyl)-propanoate (4NO2PDPMe) and methyl 3-(4-aminophthalimido)-3-(3,4-dimethoxyphenyl)-propanoate...


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