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전체 선택해제
총 218건 검색
본문검색 결과만 보기
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Neurotensin Enhances Gastric Motility in Antral Circular Muscle Strip of Guinea-pig
TaeYongKoh, SungJoonKim, SangJinLee, TongMookKang, JaeYeoulJun, JaeHoonSim, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 7 227-234 (8 pages)
Many reports suggest that neurotensin (NT) in the gastrointestinal tract may play a possible role as a neurotransmitter, a circulating hormone, or a modulator of motor activity. NT exerts various actions in the intestine; it produces contractile and relaxant responses in intestinal smooth muscle. This study was designed to investigate the effect of NT on motility of antral circular muscle strips in guinea-pig stomach. To assess the role of Ca2 influx in underlying mechanism, slow waves... -
Relatoinship between Sarcoplasmic Reticular Calcium Release and Na+-Ca2+ Exchange in the Rat Myocardial Contraction
Eun-GiKim, SoonJinKim, ChangMannKo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 4 197-210 (14 pages)
Suppressive role of Na-Ca2 exchange in myocardial tension generation was examined in the negative frequency-force relationship (FFR) of electric field stimulated left atria (LA) from postnatal developing rat heart and in the whole-cell clamped adult rat ventricular myocytes with high concentration of intracellular Ca2 buffer (14 mM EGTA). LA twitch amplitudes, which were suppressed by cyclopiazonic acid in a postnatal age-dependent manner, elicited frequency-dependent and... -
The Effects of Sera from Amyotrophic Lateral Sclerosis Patients on Neuromuscular Transmission and Calcium Channels in Mice
HaiDunYan, JimokKim, SungJunJung, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 17 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 13 101-117 (17 pages)
Amyotrophic lateral sclerosis (ALS) is a degenerative neuromuscular disease of unknown etiology in which the upper and lower motor neurons are progressively destroyed. Recent evidences support the role of autoimmune mechanisms in the pathogenesis of ALS. This study investigated the effects of sera from ALS patients on neuromuscular transmission in phrenic nerve-hemidiaphragm preparations and on calcium currents of single isolated dorsal root ganglion (DRG) cells in mice. Mice were injected with... -
Roles of Na+-Ca2+ Exchange in the Negative Force-Frequency Relationship
ChangMannKoSoonJinKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 8 715-724 (10 pages)
Frequency-force relationships (FFR) were studied in electrically field stimulated rat left atria (LA) by reducing the stimulation frequency from resting 3 Hz to test frequencies (0.1-1 Hz) for 5 minutes. The twitch amplitudes of LA elicited the typical negative staircases with 3-phased changes: the initial rapid increase, the second decrease and the following plateau at test frequencies. Verapamil (3⁓105 M) pretreatment elicited frequency-dependent suppression of the twitch... -
Comparision of Regulatory Action of cAMP and cGMP on the Activation of Neutrophil Responses
Chang-HwangHan, Young-ChulYoon, Yong-KyooShin, Eun-SookHan, Chung-SooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 13 97-105 (9 pages)
fMLP but effectively inhibited the sustained rise. On the other hand, BrcGMP significantly inhibited both phases. fMLP-induced Mn2 influx was inhibited by either DBcAMP or BrcGMP. These results suggest that fMLP-stimulated neutrophil responses may be regulated by cAMP more than cGMP. cAMP and cGMP appear not affect stimulated responses by direct protein kinase C activation. Their regulatory action on the stimulated neutrophil responses may be not influenced by other activation processes. -
Pharmacological Evidence that Cromakalim Inhibits Ca2+ Release from Intracellular Stores in Porcine Coronary Artery
ByungYongRhim, SunHwaHong, ChiDaeKim, WonSukLee, KiWhanHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 4 27-34 (8 pages)
In the present study, it was aimed to further indentify the intracellular action mechansm of cromakalim and levcromakalim in the porcine coronary artery. In intact porcine coronary arterial strips loaded with fura-2/AM, acetylcholine caused an increase in intracellular free Ca2 ([Ca2]i) in association with a contraction in a concentration-dependent manner. Cromakalim (1 ㄍM) caused a reduction in acetylcholine-induced increased [Ca2]i not only in the mormal... -
외상후 스트레스장애 환자에 대한 P300의 임상적 적용
김형주, 오성희, 이승환 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 2009, 제 48권 제 6호 7 461-467 (7 pages)
