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본문검색 결과만 보기
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Increased HoxB4 Inhibits Apoptotic Cell Death in Pro-B Cells
Sung-WonPark, Kyung-JongWon, Yong-SooLee, HyeSunKim, Yu-KyungKim, Hyeon-WooLee, BokyungKim, ByeongHanLee, Jin-HoiKim, Dong-KuKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 6 265-271 (7 pages)
HoxB4, a homeodomain-containing transcription factor, is involved in the expansion of hematopoietic stem cells and progenitor cells in vivo and in vitro, and plays a key role in regulating the balance between hematopoietic stem cell renewal and cell differentiation. However, the biological activity of HoxB4 in other cells has not been reported. In this study, we investigated the effect of overexpressed HoxB4 on cell survival under various conditions that induce death, using the Ba/F3 cell line.... -
Chronic Opium Treatment Can Differentially Induce Brain and Liver Cells Apoptosis in Diabetic and Non-diabetic Male and Female Rats
MajidAsiabanha, GholamrezaAsadikaram, AmirRahnema, MehdiMahmoodi, GholamhoseinHasanshahi, MohammadHashemi6, MohammadKhaksari 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 2 327-332 (6 pages)
It has been shown that some opium derivatives promote cell death via apoptosis. This study was designed to examine the influence of opium addiction on brain and liver cells apoptosis in male and female diabetic and non-diabetic Wistar rats. This experimental study was performed on normal, opium-addicted, diabetic and diabetic opium-addicted male and female rats. Apoptosis was evaluated by TUNEL and DNA fragmentation assays. Results of this study showed that apoptosis in opium-addicted and... -
Dendritic Cells-based Vaccine and Immune Monitoring for Hepatocellular Carcinoma
Dae-HeuiLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 2 11-14 (4 pages)
Human tumors, including those of the hepatobiliary system, express a number of specific antigens that can be recognized by T cells, and may provide potential targets for cancer immunotherapy. Dendritic cells (DCs) are rare leucocytes that are uniquely potent in their ability to capture, process and present antigens to T cells. The ability to culture sufficient numbers of DCs from human bone marrow or blood progenitors has attracted a great deal of interest in their potential utilization in human... -
Effects of Antioxidants on the Gamma-Radiation Damage of the Cultured Vascular Smooth Mucle Cells of Rat Aorta
Jong-DooLee, Hyoung-ChulChoi, Young-JinKang, Myung-SeKim, Kwang-YounLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.5 5 189-195 (7 pages)
To study the protective effects of antioxidants on the radiation damages of the cells, vascular smooth muscle cells (VSMC) from thoracic aorta of Sprague-Dawley rats were cultured and irradiated with gamma-ray. Cell viability was measured by direct cell counting and MTT assay, and flow cytometry was performed to measure fractional distributions of the cells. Gamma-ray irradiation inhibited cell proliferations accompanied with decreased G1 phase and increased S- and G2/M phases, and the maximum... -
A Systematic Review and Meta-Analysis of Applicability of Web-Based Interventions for Individuals with Depression and Quality of Life Impairment
Danbi Yang, Ji-Won Hur, Yoo Bin Kwak, Sung-Won Choi 대한신경정신의학회 Psychiatry Investigation 8 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 3 759-766 (8 pages)
Objective_The purpose of this meta-analysis was to determine the applicability of web-based treatment programs for individuals with depression and quality of life impairments. Methods_We conducted database and manual searches using imprecise search-term strategy and inclusion criteria. Research published from 2005 to December 2015 was included in this study. Upon review, a total of 12 published papers on web-based intervention for individuals with depression were assessed eligible for this... -
DSM-III-R 주요우울증에 대한 한국어판 Geriatric Depression Scale(GDS)의 진단적 타당성 연구
조맹제, 배재남, 서국희, 함봉진, 김장규, 이동우, 강민희 대한신경정신의학회 신경정신의학 16 Pages
대한신경정신의학회 신경정신의학 1999, 제 38권 제 1호 4 48-63 (16 pages)
연구목적： 본 연구는 노인성 우울증의 선별 검사도구로 전세계적으로 널리 사용되고 있는 Geriatric Deression Scale(GDS) 및 축약형 GDS(SGDS)가 우리나라에서도 타당성 있게 사용될 수 있는지 평가하기 위한 것 이다. 방 법： 3차례의 예비연구 과정을 거쳐서 우울증 선별 검사도구인 한국판 GDS을 제작한 후에, 88명의 임상환자군 을 대상으로 한국판 GDS의 신뢰도와 타당도 검증, 주요우울증의 선별을 위한 최적절단점 추정, ROC커브 를 이용한 진단적 타당성 분석을 하였으며, 15문항의 한국판 SGDS에 대한 표준화 연구도 아울러... -
Virulence Structure of Blumeria graminis f. sp. avenae Populations in Poland across 2014-2015
Magdalena Cieplak, Katarzyna Terlecka, Tomasz Ociepa, Beata Zimowska, Sylwia Oko? 한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 2호 3 115-123 (9 pages)
The purpose of this study was to determine the viru- lence structure of oat powdery mildew (Blumeria grami- nis f. sp. avenae, Bga) populations in Poland collected in 2014 and 2015. Powdery mildew isolates were collected from 18 locations in Poland. In total, nine lines and cultivars of oat, with different mildew resistance genes, were used to assess virulence of 180 isolates. The results showed that a significant proportion of the Bga isolates found in Poland were virulent to differentials with... -
Inhibitory Activity of Sedum middendorffianum-Derived 4-Hydroxybenzoic Acid and Vanillic Acid on the Type III Secretion System of Pseudomonas syringae pv. tomato DC3000
Ji Eun Kang, Byeong Jun Jeon, Min Young Park, Beom Seok Kim 한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 6호 8 608-617 (10 pages)
The type III secretion system (T3SS) is a key virulence determinant in the infection process of Pseudomonas syringae pv. tomato DC3000 (Pst DC3000). Pathogen constructs a type III apparatus to translocate effector proteins into host cells, which have various roles in pathogenesis. 4-Hydroxybenozic acid and vanillic acid were identified from root extract of Sedum middendorffianum to have inhibitory effect on promoter activity of hrpA gene encoding the structural protein of the T3SS apparatus. The... -
Inhibition of the Aspergillus flavus Growth and Aflatoxin B1 Contamination on Pistachio Nut by Fengycin and Surfactin-Producing Bacillus subtilis UTBSP1
한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2016, 32권 3호 5 209-215 (7 pages)
In this study, the treatment of pistachio nuts by Bacillus subtilis UTBSP1, a promising isolate to degrade aflatoxin B1 (AFB1), caused to reduce the growth of Aspergillus flavus R5 and AFB1 content on pistachio nuts. Fluorescence probes revealed that the cell free supernatant fluid from UTBSP1 affects spore viability considerably. Using high-performance liquid chromatographic (HPLC) method, 10 fractions were separated and collected from methanol extract of cell free supernatant fluid. Two... -
Effect of X-irradiation on Citrus Canker Pathogen Xanthomonas citri subsp. citri of Satsuma Mandarin Fruits
한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2015, 31권 4호 3 343-349 (7 pages)
Citrus canker caused by Xanthomonas citri subsp. citri (Xcc) is one of the most important bacterial diseases of citrus. Because citrus canker is not found in many countries including European Union and Australia, Xcc is strictly regulated in order to prevent its spread. In this study, the effects of X-irradiation on Xcc growth either in the suspension or on the surface of citrus fruits were investigated. The suspension containing 1×10 cfu/ml of Xcc was irradiated with different absorbed doses...
