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61.

In vivo metabolism of Talosin A, new isoflavonol glycoside from Kitasatospora kifunensis, in rats

Jong-Hwan Lim, In-Bae Song, Youn-Hwan Hwang, Myoung-Seok Kim, Jong-Woo Kim, Jin-Yong Kim, Joo Won Suh, Hyo-In Yun 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 2호 2 115-120 (6 pages)

Jong-Hwan Lim, In-Bae Song, Youn-Hwan Hwang, Myoung-Seok Kim, Jong-Woo Kim, Jin-Yong Kim, Joo Won Suh, Hyo-In Yun 저
...
- 3,000원
The isoflavonol glycoside Talosin A, genistein (GT)-7-a-L-6- deoxy talopyranose (GT-Tal), was first isolated from the culture broth of Kitasatospora kifunensis MJM341. The aim of the present study was to evaluate the oral absorption and metabolism of the newly isolated isoflavonol glycoside, GT-Tal compared to genistin (GT-7-O-b-D-glucopyranoside; GT- Glu). Free GT-Glu and GT-Tal could not be detected prior to enzymatic hydrolysis of the corresponding conjugates in rat plasma. Following oral...
62.

Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits

B. H. Pavithra, N. Prakash*, K. Jayakumar 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 3 293-297 (5 pages)

B. H. Pavithra, N. Prakash*, K. Jayakumar 저
...
- 1,500원
norfloxacin was adequately described by a one- compartment open model. The pharmacokinetic data revealed that curcumin-treated animals had significantly (p ≤ 0.05) higher area under the plasma concentration- time curve and area under the first moment of plasma drug concentration-time curve. Prior treatment of curcumin significantly (p ≤ 0.05) increased elimination half-life and volume of distribution of norfloxacin. Further treatment with curcumin reduced loading and maintenance dose...
63.

Disposition kinetics and urinary excretion of ciprofloxacin in goats following single intravenous administration

R. Raina, S. Prawez*, D.J. Dimitrova, N.K. Pankaj, P.K. Verma 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 3호 3 241-246 (6 pages)

R. Raina, S. Prawez*, D.J. Dimitrova, N.K. Pankaj, P.K. Verma 저
...
- 3,000원
We evaluated the pharmacokinetics of ciprofloxacin in serum (n = 6) and urine (n = 4) in goats following a single intravenous administration of 4 mg/kg body weight. The serum concentration-time curves of ciprofloxacin were best fitted by a two-compartment open model. The drug was detected in goat serum up to 12 h. The elimination rate constant (b) and elimination half-life (t1/2b) were 0.446 ± 0.04 h and 1.630 ± 0.17 h, respectively. The apparent volume of distribution at steady state...
64.

Contribution of the xenograft bone plate-screw system in lumbar transpedicular stabilization of dogs: an in-vitro study

Hakan Salci*, Sani Sarigul, Seref Dogan, Huseyin Lekesiz, Resat Ozcan, O. Sacit Gorgul, Kaya Aksoy 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 2호 10 193-196 (4 pages)

Hakan Salci*, Sani Sarigul, Seref Dogan, Huseyin Lekesiz, Resat Ozcan, O. Sacit Gorgul, Kaya Aksoy 저
...
- 1,500원
We performed biomechanical comparison of a xenograft bone plate-screw (XBPS) system for achieving cadaveric lumbar transpedicular stabilization (TS) in dogs. Twenty dogs' cadaveric L2-4 lumbar specimens were harvested and their muscles were removed, but the discs and ligaments were left intact. These specimens were separated to four groups: the L2-4 intact group as control (group I, n = 5), the L3 laminectomy and bilateral facetectomy group (LBF) (group II, n = 5), the LBF plus TS with metal...
65.

Effect of trikatu pretreatment on the pharmacokinetics of pefloxacin administered orally in mountain Gaddi goats

Madhukar S. Dama, C. Varshneya, *, M. S. Dardi, V. C. Katoch3 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 1호 4 25-29 (5 pages)

Madhukar S. Dama, C. Varshneya, *, M. S. Dardi, V. C. Katoch3 저
...
- 1,500원
the investigation revealed higher values for the area under the curve, the area under the first moment of the plasma drug concentration time curve, the mean residential time, the total duration of pharmacological action and bioavailability. Trikatu treatment, however, significantly reduced the elimination half life (t1/2Ղ) and zero time intercept of the elimination phase. The apparent volume of distribution based on the total area under the plasma drug concentration curve [(Vd(area)] and...
66.

Disposition kinetics and dosage regimen of levofloxacin on concomitant administration with paracetamol in crossbred calves

Vinod K. Dumka* 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 7 357-360 (4 pages)

Vinod K. Dumka* 저
...
- 1,500원
The disposition kinetics of levofloxacin was investigated in six male crossbred calves following single intravenous administration, at a dose of 4 mg/kg body weight, into the jugular vein subsequent to a single intramuscular injection of paracetamol (50 mg/kg). At 1 min after the injection of levofloxacin, the concentration of levofloxacin in plasma was 17.2±0.36 ■g/ml, which rapidly declined to 6.39±0.16 ■g/ml at 10 min. The drug level above the MIC90 in plasma, was detected for up...
67.

Clinical pharmacokinetics of norfloxacin-glycine acetate after intravenous and oral administration in pigs

Zhi-Qiang Chang, Byung-Chol Oh, Jong-Choon Kim, Kyu-Shik Jeong, Myung-Heon Lee, Hyo-In Yun, Mi-Hyun Hwang, Seung-Chun Park* 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 6 353-356 (4 pages)

Zhi-Qiang Chang, Byung-Chol Oh, Jong-Choon Kim, Kyu-Shik Jeong, Myung-Heon Lee, Hyo-In Yun, Mi-Hyun Hwang, Seung-Chun Park* 저
...
- 1,500원
The pharmacokinetics and dosage regimen of norfloxacin-glycine acetate (NFLXGA) was investigated in pigs after a single intravenous (i.v.) or oral (p.o.) administration at a dosage of 7.2 mg/kg body weight. After both i.v. and p.o. administration, plasma drug concentrations were best fitted to an open two-compartment model with a rapid distribution phase. After i.v. administration of NFLXGA, the distribution (t1/2■)and elimination half-life (t1/2■) were 0.36 ± 0.07 h and 7.42 ± 3.55...
68.

Disposition kinetics and urinary excretion of cefpirome after intravenous injection in buffalo calves

Neetu Rajput, Vinod K. Dumka, Harpal S. Sandhu 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 4 21-25 (5 pages)

Neetu Rajput, Vinod K. Dumka, Harpal S. Sandhu 저
...
- 1,500원
We investigated the disposition kinetics and urinary excretion of cefpirome in buffalo calves after a single intravenous administration of 10 mg/kg. Also, an appropriate dosage regimen was calculated. At 1 min after injection, the concentration of cefpirome in the plasma was 57.4 ± 0.72 μg/ml, which declined to 0.22 ± 0.01 μg/ml at 24 h. The cefpirome was rapidly distributed from the blood to the tissue compartment as shown by the high distribution coefficient values (8.67 ± 0.46/h), and by...
69.

Pharmacokinetics, urinary excretion and dosage regimen of levofloxacin following a single intramuscular administration in cross bred calves

Vinod K. Dumka, Anil K. Srivastava 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 5 333-337 (5 pages)

Vinod K. Dumka, Anil K. Srivastava 저
...
- 1,500원
The pharmacokinetics and urinary excretion following single intramuscular administration of levofloxacin at a dose of 4 mg/kg was investigated in seven male cross bred calves. Appreciable plasma concentration of levofloxacin (0.38 ± 0.06 μg/ml) was detected at 1 min after injection and the peak plasma level of 3.07 ± 0.08 μg/ml was observed at 1 h. The drug level above MIC90 in plasma was detected up to 12 h after administration. Rapid absorption of the drug was also evident by the high...
70.

Pharmacokinetics and bioavailability of doxycycline in ostriches (Struthio camelus) at two different dose rates

Ehab A. Abu-Basha, Nasir M. Idkaidek, Tareq M. Hantash 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 4 327-332 (6 pages)

Ehab A. Abu-Basha, Nasir M. Idkaidek, Tareq M. Hantash 저
...
- 3,000원
after administration. The plasma concentration-time curves were examined using non-compartmental methods based on the statistical moment theory for only the higher dose. After IV administration, the elimination half-life (t1/2β), mean residence time (MRT), volume of distribution at the steady-state (Vss), volume of distribution (Vdarea) and total body clearance (ClB) were 7.67 ± 0.62 h, 6.68 ± 0.86 h, 0.86 ± 0.16 l/kg, 1.67 ± 0.52 l/kg and 2.51 ± 0.63 ml/min/kg, respectively. After IM and...

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