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61.

Effect of Sulfonylureas Administered Centrally on the Blood Glucose Level in Immobilization Stress Model

NaveenSharma, Yun-BeomSim, Soo-HyunPark, Su-MinLim, Sung-SuKim, Jun-SubJung, Jae-SeungHong, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 2 197-202 (6 pages)

NaveenSharma, Yun-BeomSim, Soo-HyunPark, Su-MinLim, Sung-SuKim, Jun-SubJung, Jae-SeungHong, Hong-WonSuh 저
...
- 3,000원
Sulfonylureas are widely used as an antidiabetic drug. In the present study, the effects of sulfonylurea administered supraspinally on immobilization stress-induced blood glucose level were studied in ICR mice. Mice were once enforced into immobilization stress for 30 min and returned to the cage. The blood glucose level was measured 30, 60, and 120 min after immobilization stress initiation. We found that intracerebroventricular (i.c.v.) injection with 30 μg of glyburide, glipizide,...
62.

Effect of the Combination of CI-988 and Morphine on Neuropathic Pain after Spinal Cord Injury in Rats

JunesunKim, YoungkyungKim, Suk-ChanHahm, YoungWookYoon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 7 125-130 (6 pages)

JunesunKim, YoungkyungKim, Suk-ChanHahm, YoungWookYoon 저
...
- 3,000원
Cholecystokinin is known to be involved in the modulation of nociception and to reduce the efficacy of morphine analgesia. This study investigated the effects of intrathecal administration of morphine and the cholecystokinin type B antagonist CI-988 on below-level neuropathic pain after spinal cord injury in rats. We also examined the interaction of morphine and CI-988 in the antinociceptive effect. Both morphine and CI-988 given individually increased the paw withdrawal threshold to mechanical...
63.

Effects of Acupuncture Stimulation at Different Acupoints on Formalin-Induced Pain in Rats

KyungHaChang, SunJoonBai, HyejungLee, BaeHwanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 5 121-127 (7 pages)

KyungHaChang, SunJoonBai, HyejungLee, BaeHwanLee 저
...
- 3,000원
Acupuncture is the process of stimulating skin regions called meridians or acupoints and has been used to treat pain-related symptoms. However, the pain-relieving effects of acupuncture may be different depending on acupoints. In the present study, the effects of acupuncture on behavioral responses and c-Fos expression were evaluated using a formalin test in male Sprague-Dawley rats in order to clarify the analgesic effects of three different acupoints. Each rat received manual acupuncture at...
64.

Naloxone Postconditioning Alleviates Rat Myocardial Ischemia Reperfusion Injury by Inhibiting JNK Activity

AnzhouXia, ZhiXue, WeiWang, TanZhang, TiantianWei, XingzhiSha, YixunDing, WeidongZhou 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.1 9 67-72 (6 pages)

AnzhouXia, ZhiXue, WeiWang, TanZhang, TiantianWei, XingzhiSha, YixunDing, WeidongZhou 저
...
- 3,000원
To investigate the alteration of c-Jun N-terminal kinase (JNK) activity after myocardial ischemia reperfusion injury (MIRI) and further explore the effect of naloxone postconditioning on MIRI. Forty male Sprague Dawley rats were randomly divided into five groups: sham operation (sham, n=8); ischemia reperfusion (IR, n=8); IR+naloxone 0.5 mg/kg (Nal L, n=8); IR+naloxone 1.0 mg/kg (Nal M, n=8); IR+naloxone 2.0 mg/kg (Nal H, n=8). Pathological changes of myocardial tissue were visualized by HE...
65.

Electroacupuncture Analgesia Is Improved by Adenoviral Gene Transfer of Dopamine Beta-hydroxylase into the Hypothalamus of Rats

Soo-JeongKim, EunSookChung, Jun-HoLee, ChangHoonLee, SunKwangKim, Hye-JungLee, HyunsuBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 5 505-510 (6 pages)

Soo-JeongKim, EunSookChung, Jun-HoLee, ChangHoonLee, SunKwangKim, Hye-JungLee, HyunsuBae 저
...
- 3,000원
Electroacupuncture (EA) is a modified form of acupuncture that utilizes electrical stimulation. We previously showed that EA stimulated rats were divided into responders that were sensitive to EA and non-responders that were insensitive to EA based on the tail flick latency (TFL) test. The dopamine beta-hydroxylase (DBH) gene was more abundantly expressed in the hypothalamus of responder rats than non-responder rats. To determine whether overexpression of DBH gene expression in the hypo-thalamus...
66.

Ineffective Doses of Dexmedetomidine Potentiates the Antinoci-ception Induced by Morphine and Fentanyl in Acute Pain Model

MuminUnal, SinanGursoy, AhmetAltun, CevdetDuger, IclalOzdemirKol, KenanKaygusuz, IhsanBagcivan, CanerMimaroglu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 6 417-422 (6 pages)

MuminUnal, SinanGursoy, AhmetAltun, CevdetDuger, IclalOzdemirKol, KenanKaygusuz, IhsanBagcivan, CanerMimaroglu 저
...
- 3,000원
The aim of this study was to evaluate the synergistic potentiation effect of ineffective doses of dexmedetomidine on antinociception induced by morphine and fentanyl in acute pain model in rats. Seventy albino Wistar rats were separated into 7 groups. Data for the control and sham groups were recorded. The ineffective dose of dexmedetomidine was investigated and found to be 3 Ռg/kg. Each group was administered the following medications: 3 mg/kg morphine (intraperitoneal) to Group 3, 5...
67.

A Review on Renal Toxicity Profile of Common Abusive Drugs

VarunParkashSingh, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 13 347-357 (11 pages)

VarunParkashSingh, NirmalSingh, AmteshwarSinghJaggi 저
...
- 4,000원
Drug abuse has become a major social problem of the modern world and majority of these abusive drugs or their metabolites are excreted through the kidneys and, thus, the renal complications of these drugs are very common. Morphine, heroin, cocaine, nicotine and alcohol are the most commonly abused drugs, and their use is associated with various types of renal toxicity. The renal complications include a wide range of glomerular, interstitial and vascular diseases leading to acute or chronic renal...
68.

Changes in c-Fos Expression in the Forced Swimming Test: Common and Distinct Modulation in Rat Brain by Desipramine and Citalopram

SunHyeChoi, SungChung, JinHeeCho, YunHaCho, JinWookKim, JeongMinKim, HeeJeongKim, HyunJuKim, KyungHoShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 10 321-329 (9 pages)

SunHyeChoi, SungChung, JinHeeCho, YunHaCho, JinWookKim, JeongMinKim, HeeJeongKim, HyunJuKim, KyungHoShin 저
...
- 3,000원
Rodents exposed to a 15-min pretest swim in the forced swimming test (FST) exhibit prolonged immobility in a subsequent 5-min test swim, and antidepressant treatment before the test swim reduces immobility. At present, neuronal circuits recruited by antidepressant before the test swim remain unclear, and also less is known about whether antidepressants with different mechanisms of action could influence neural circuits differentially. To reveal the neural circuits associated with antidepressant...
69.

Ginsenosides Have a Suppressive Effect on c-Fos Expression in Brain and Reduce Cardiovascular Responses Increased by Noxious Stimulation to the Rat Tooth

Ji-YeonJung, Kyung-JooSeong, In-OhkMoon, Jin-HyoungCho, , Sun-HunKim, Won-JaeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.2 2 121-125 (5 pages)

Ji-YeonJung, Kyung-JooSeong, In-OhkMoon, Jin-HyoungCho, , Sun-HunKim, Won-JaeKim 저
...
- 1,500원
hypothalamic supraoptic nucleus (SON) and paraventricular nucleus (PVN), central cardiovascular regulation centers. Ginsenosides reduced the number of c-Fos-IR increased by NS to tooth in the trigeminal Vc and thalamic VPMN and CLN. Naloxone, an opioid antagonist, did not block the effect of ginsenoside on the number of Fos-IR neurons enhanced by NS to tooth in the trigeminal Vc and thalamic VPMN and CLN. Ginsenosides ameliorated arterial BP and HR raised by NS to tooth and reduced the number of...
70.

Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons

YunjuJin, JunKim, JiyeonKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 10 211-217 (7 pages)

YunjuJin, JunKim, JiyeonKwak 저
...
- 3,000원
Recent studies have demonstrated that nitric oxide (NO) activates transient receptor potential vanilloid subtype 1 (TRPV1) via S-nitrosylation of the channel protein. NO also modulates various cellular functions via activation of the soluble guanylyl cyclase (sGC)/protein kinase G (PKG) pathway and the direct modification of proteins. Thus, in the present study, we investigated whether NO could indirectly modulate the activity of TRPV1 via a cGMP/PKG-dependent pathway in cultured rat dorsal root...

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