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61.

Influence of Tacrine on Catecholamine Secretion in the Perfused Rat Adrenal Gland

Seok-JeongJang, Won-HoYang, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.4 6 207-214 (8 pages)

Seok-JeongJang, Won-HoYang, Dong-YoonLim 저
...
- 3,000원
The present study was designed to clarify whether tacrine affects the release of catecholamines (CA) from the isolated perfused model of rat adrenal gland or not and to elucidate the mechanism of its action. Tacrine (3⁓10⁣5∼3⁓10⁣4 M) perfused into an adrenal vein for 60 min inhibited CA secretory responses evoked by ACh (5.32⁓10⁣3 M), DMPP (a selective neuronal nicotinic agonist, 10⁣4 M for 2 min) and McN-A-343 (a selective muscarinic M1-agonist,...
62.

GLUT Phosphorylation May be Required to GLUT Translocation Mechanism

Jong-SikHah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 8 487-496 (10 pages)

Jong-SikHah 저
...
- 3,000원
In this work, GLUTs phosphorylations by a downstream effector of PI3-kinase, PKC-ζ, were studied, and GLUT4 phosphorylation was compared with GLUT2 phosphorylation in relation to the translocation mechanism. Prior to phosphorylation experiment, PKC-ζ kinase activity was determined as 20.76⁑4.09 pmoles Pi/min/25 ng enzymes. GLUT4 was phosphorylated by PKC-ζ and the phosphorylation was increased on the vesicles immunoadsorpted from LDM and on GLUT4 immunoprecipitated from GLUT4-...
63.

Comparative Effects of PKB-α and PKC-ζ on the Phosphorylation of GLUT4-Containing Vesicles in Rat Adipocytes

Jong-SikHah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 7 479-486 (8 pages)

Jong-SikHah 저
...
- 3,000원
Insulin stimulates glucose transport in muscle and fat cells by promoting the translocation of glucose transporter (GLUT4) to the cell surface. Phosphatidylinositide 3-kinase (PI3-kinase) has been implicated in this process. However, the involvement of protein kinase B (PKB)/Akt and PKC-ζ, those are known as the downstream target of PI3-kinase in regulation of GLUT4 translocation, is not known yet. An interesting possibility is that these protein kinases phosphorylate GLUT4 directly in this...
64.

Postnatal Changes in Atrial Compliance and Stretch-Induced ANP Secretion in Rabbits

SuhnHeeKim, KyungSunLee, SungZooKim, KyungHwanSeul, KyungWooCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 8 393-401 (9 pages)

SuhnHeeKim, KyungSunLee, SungZooKim, KyungHwanSeul, KyungWooCho 저
...
- 3,000원
To define the postnatal changes in ANP secretion in response to mechanical stretch and atrial compliance, experiments have been done in perfused nonbeating rabbit atria with different ages: 1-day, 1-, 2-, 3-, 4-, and 8-wk-old. In 1-day-old-rabbits, an increase in intraatrial pressure resulted in an increase in atrial volume, which was higher than that in 1-wk-old rabbits. Increases in atrial volume stimulated the secretion of ANP with concomitant translocation of extracellular fluid (ECF) into...
65.

Influence of Staurosporine on Catecholamine Release Evoked by Cholinergic Stimulation and Membrane Depolarization from the Rat Adrenal Gland

Dong-YoonLim, Yeon-SooChoi, Won-HoYang, Yong-KyoonLee, YongLim, Cheol-HeeChoi, Byung-SikYu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.2 10 149-158 (10 pages)

Dong-YoonLim, Yeon-SooChoi, Won-HoYang, Yong-KyoonLee, YongLim, Cheol-HeeChoi, Byung-SikYu 저
...
- 3,000원
The present study was attempted to examine the effect of staurosporine (STS) on secretion of catecholamines (CA) evoked by cholinergic stimulation and membrane depolarization from the isolated perfused rat adrenal gland and to establish its mechanism of action. The perfusion of STS (3⁓10⁣7∼3⁓10⁣8 M) into an adrenal vein for 20 min produced a dose-dependent inhibition in CA secretion evoked by ACh (5.32⁓10⁣3 M), high K⁢ (5.6⁓10⁣2 M), DMPP...
66.

Involvement of Spontaneously Formed Cyclic Nucleotides in Cat Gastric Muscle Relaxation

Sang-SooSim, Hye-JungBaek, Duck-JooRhie, Shin-HeeYoon, SangJuneHahn, Yang-HyeokJo, Myung-SukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 5 275-282 (8 pages)

Sang-SooSim, Hye-JungBaek, Duck-JooRhie, Shin-HeeYoon, SangJuneHahn, Yang-HyeokJo, Myung-SukKim 저
...
- 3,000원
Muscle strips and muscle cells from cat stomach were used to investigate whether spontaneously formed cyclic nucleotides were involved in the inhibition of gastric smooth muscle contraction. A phosphodiesterase inhibitor, 3-isobutyl-1-methylxanthine (IBMX), increased the levels of both cyclic GMP (cGMP) and cyclic AMP (cAMP) in resting state cells, while decreasing acetylcholine-induced muscle contraction. Under the influence of IBMX, SQ22536, an adenylyl cyclase inhibitor and methylene blue, a...
67.

cAMP-Dependent Signalling is Involved in Adenosine-Stimulated Cl⁣ Secretion in Rabbit Colon Mucosa

SaeOckOh, EuiYongKim, JinSupJung, JaeSukWoo, YongKeunKim, SangHoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 14 521-527 (7 pages)

SaeOckOh, EuiYongKim, JinSupJung, JaeSukWoo, YongKeunKim, SangHoLee 저
...
- 3,000원
through a cAMP-dependent Cl⁣ channel. The rank order of potencies of adenosine receptor agonists was 5'-(N-ethylcarboxamino)adenosine(NECA)＞N6-(R-phenylisopropyl)adenosine(R- PIA)＞2-[p-(2-carbonylethyl)-phenyl-ethylamino]-5'-N-ethylcarboxaminoadenosine(CGS21680). From the above results, it can be concluded that adenosine interacts with the A2b adenosine receptor in the rabbit colon mucosa and a cAMP-dependent signalling mechanism underlies the stimulation of Cl⁣ secretion.
68.

Mechanism of Vasoactive Intestinal Polypeptide-Induced Catecholamine Secretion from the Rat Adrenal Medulla

Dong-YoonLim, Jae-BongHeo, Cheol-HeeChoi, Geon-HanLim, Yong-GyoonLee, Song-HoonOh, Il-SikKim, Jong-InKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 6 443-454 (12 pages)

Dong-YoonLim, Jae-BongHeo, Cheol-HeeChoi, Geon-HanLim, Yong-GyoonLee, Song-HoonOh, Il-SikKim, Jong-InKim 저
...
- 4,100원
The present study was attempted to investigate the effect of vasoactive intestinal polypeptide (VIP) on secretion of catecholamines (CA) and to establish whether there is the existence of a noncholinergic mechanism in adrenomedullary CA secretion from the isolated perfused rat adrenal gland. The perfusion into an adrenal vein of VIP (3⁓10⁣6 M) for 5 min or the injection of acetylcholine (ACh, 5.32⁓10⁣3 M) resulted in great increases in CA secretion. Tachyphylaxis to...
69.

Inhibitory Effects of Ginseng Saponins on c-fos mRNA Expression and the Proliferation of Rat Aortic Vascular Smooth Muscle Cells Stimulated by Angiotensin II

WoongChoi, JinYoungJung, HunSikKim, YeoPyoYun, JongDaePark, HeeYulAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 8 201-207 (7 pages)

WoongChoi, JinYoungJung, HunSikKim, YeoPyoYun, JongDaePark, HeeYulAhn 저
...
- 3,000원
and PT (1.0 mg/ml) suppressed c-fos mRNA induction in VSMCs stimulated by 10-5 M Ang II. The order of inhibitory potency was PT>TS. Ginseng saponins (0.01∼1.0 mg/ml) inhibited the proliferation of VSMCs stimulated by Ang II in a concentration dependent manner, the inhibitory potency was TS＞PT＞PD at 0.1∼1.0 mg/ml. These results suggest that ginseng saponins may suppress Ang II-stimulated proliferation of aortic VSMCs which can be seen in atherosclerosis, hypertension and restenosis.
70.

Influence of Glucocorticoids on Cholinergic Stimulation-Induced Catecholamine Secretion from the Rat Adrenal Medulla

Dong-YoonLim, Jae-JoonLee, Oh-SeongGweon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 5 173-184 (12 pages)

Dong-YoonLim, Jae-JoonLee, Oh-SeongGweon 저
...
- 4,100원
The present study was undertaken to examine the influence of glucocorticoids on the secretory responses of catecholamines (CA) evoked by acetylcholine (ACh), DMPP, McN-A-343, excess K+ and Bay-K-8644 from the isolated perfused rat adrenal gland and to clarify the mechanism of its action. The perfusion of the synthetic glucocorticoid dexamethasone (10-100 ՌM) into an adrenal vein for 20 min produced a dose-dependent inhibition in CA secretion evoked by ACh (5.32 mM), excess K+ (a...

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