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양측성 구순구개열 환자 증례에서 상악 전진술을 통한 안모개선: 증례보고
윤미수, 한영집, 경희문, 홍미희 대한구순구개열학회 대한구순구개열학회지 8 Pages
대한구순구개열학회 대한구순구개열학회지 2018, 제 21권 2호 5 68-75 (8 pages)
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성장 이후 교정치료와 골이식을 동반한 구순구개열 환자의 골결손 부위 임플란트 치험례
박진호, 김다소미, 정휘동, 차정열 대한구순구개열학회 대한구순구개열학회지 6 Pages
대한구순구개열학회 대한구순구개열학회지 2018, 제 21권 1호 4 17-22 (6 pages)
We report the case of an unilateral alveolar cleft man who was performed orthodontic treatment and dental implant after autogenous bone graft on cleft site with bone of ramus. We achieved improvement of implant esthetics by multidisciplinary treatment approach in cleft patient. A 35-year-old man with skeletal class I and unilateral alveolar cleft, we planned to graft ramus bone on cleft site, perform orthodontic treatment and to place implant on missing area. For bone graft on the cleft site, we... -
18번 염색체 단완 결실 증후군 환자의 교정 치료 치험례
손우성, 노태경, 김성훈 대한구순구개열학회 대한구순구개열학회지 10 Pages
대한구순구개열학회 대한구순구개열학회지 2016, 제 19권 1호 1 1-10 (10 pages)
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선천성 구순구개열 환자의 장기적인 교정 치료 및 음성언어학적 고찰
홍지숙, 김윤지, 황용인, 김대성, 박양호 대한구순구개열학회 대한구순구개열학회지 13 Pages
대한구순구개열학회 대한구순구개열학회지 2009, 제 12권 1호 2 7-19 (13 pages)
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혀의 림프관종이 동반된 개방교합 환자의 교정 치료
손우성, 정종현, 김근령, 손시은, 이원재, 김용덕 대한구순구개열학회 대한구순구개열학회지 20 Pages
대한구순구개열학회 대한구순구개열학회지 2017, 제 20권 1호 1 1-20 (20 pages)
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Protein kinase C beta II upregulates intercellular adhesion molecule-1 via mitochondrial activation in cultured endothelial cells
HeeKyoungJoo, YuRanLee, SungaChoi, MyoungSooPark, GunKang, Cuk-SeongKim, ByeongHwaJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.4 3 377-384 (8 pages)
Activation of protein kinase C (PKC) is closely linked with endothelial dysfunction. However, the effect of PKCβII on endothelial dysfunction has not been characterized in cultured endothelial cells. Here, using adenoviral PKCβII gene transfer and pharmacological inhibitors, the role of PKCβII on endothelial dysfucntion was investigated in cultured endothelial cells. Phorbol 12-myristate 13-acetate (PMA) increased reactive oxygen species (ROS), p66shc phosphorylation, intracellular adhesion... -
Inhibition of ERK1/2 by silymarin in mouse mesangial cells
ChaKyungYoun, SungIlCho, MinYoungLee, YoungJinJeon, SeogKiLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 14 117-124 (8 pages)
The present study aimed to show that pro-inflammatory cytokines [tumor necrosis factor (TNF)-α, interferon (IFN)-γ, and interleukin (IL)-1β] synergistically induce the production of nitric oxide (NO) production in mouse mesangial cells, which play an important role in inflammatory glomerular injury. We also found that co-treatment with cytokines at low doses (TNF-α; 5 ng/ml, IFN-γ; 5 ng/ml, and IL-1β; 1.25 U/ml) synergistically induced NO production, whereas treatment with each cytokine... -
Silymarin Inhibits Morphological Changes in LPS-Stimulated Macrophages by Blocking NF-κB Pathway
EunJeongKim, MinYoungLee, YoungJinJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 4 211-218 (8 pages)
The present study showed that silymarin, a polyphenolic flavonoid isolated from milk thistle (Silybum marianum), inhibited lipopolysaccharide (LPS)-induced morphological changes in the mouse RAW264.7 macrophage cell line. We also showed that silymarin inhibited the nuclear translocation and transactivation activities of nuclear factor-kappa B (NF-κB), which is important for macrophage activation-associated changes in cell morphology and gene expression of inflammatory cytokines. BAY- 11-7085,... -
ERK Activation by Fucoidan Leads to Inhibition of Melanogenesis in Mel-Ab Cells
YuSeokSong, MarieCarmelBalcos, Hye-YoungYun, KwangJinBaek, NyounSooKwon, Myo-KyoungKim, Dong-SeokKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 5 29-34 (6 pages)
Fucoidan, a fucose-rich sulfated polysaccharide derived from brown seaweed in the class Phaeo-phyceae, has been widely studied for its possible health benefits. However, the potential of fucoidan as a possible treatment for hyperpigmentation is not fully understood. This study investigated the effects of fucoidan on melanogenesis and related signaling pathways using Mel-Ab cells. Fucoidan significantly decreased melanin content. While fucoidan treatment decreased tyrosinase activity, it did not... -
KHG26792 Inhibits Melanin Synthesis in Mel-Ab Cells and a Skin Equivalent Model
HailanLi, JiKim, Hoh-GyuHahn, JunYun, Hyo-SoonJeong, Hye-YoungYun, KwangJinBaek, NyounSooKwon, YoungSilMin, Kyoung-ChanPark, Dong-SeokKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 8 249-254 (6 pages)
The purpose of this study is to characterize the effects of KHG26792 (3-(naphthalen-2-yl(propoxy) methyl)azetidine hydrochloride), a potential skin whitening agent, on melanin synthesis and identify the underlying mechanism of action. Our data showed that KHG26792 significantly reduced melanin synthesis in a dose-dependent manner. Additionally, KHG26792 downregulated microphthalmiaassociated transcription factor (MITF) and tyrosinase, the rate-limiting enzyme in melanogenesis, although...


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