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691.

Inhibition of Hypoxia-induced Apoptosis in PC12 Cells by Estradiol

JiYeonJung, KwangHoonRoh, YeonJinJeong, SunHunKim, EunJuLee, MinSeokKim, WonMannOh, HeeKyunOh, WonJaeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.4 7 231-238 (8 pages)

JiYeonJung, KwangHoonRoh, YeonJinJeong, SunHunKim, EunJuLee, MinSeokKim, WonMannOh, HeeKyunOh, WonJaeKim 저
...
- 3,000원
Neuronal apoptotic events, which result in cell death, are occurred in hypoxic/ischemic conditions. Estradiol is a female sex hormone with steroid structure known to provide neuroprotection through multiple mechanisms in the central nervous system. This study was aimed to investigate the signal transduction pathway of CoCl2-induced neuronal cell death and the inhibitory effects of estradiol. Administration of CoCl2 decreased cell viability in both a dose- and time-dependent manner in PC12 cells....
692.

N-methyl-D-aspartate (NMDA) and Non-NMDA Receptors are Involved in the Production and Maintenance of Nociceptive Responses by Intraplantar Injection of Bee Venom and Melittin in the Rat

JaeHwaKim, HongKeeShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 8 179-185 (7 pages)

JaeHwaKim, HongKeeShin 저
...
- 3,000원
Whole bee venom (WBV) and its major component, melittin, have been reported to induce long-lasting spontaneous flinchings and hyperalgesia. The current study was designed to elucidate the peripheral and spinal mechanisms of N-methyl-D-aspartate (NMDA) and non-NMDA receptors by which intraplantar (i.pl.) injection of WBV and melittin induced nociceptive responses. Changes in mechanical threshold and flinching behaviors were measured after the injection of WBV (0.04 mg or 0.1 mg/paw) and melittin...
693.

Expression of Nitric Oxide Synthase and Endothelin-1 in Human Uterine Artery from Full-Term Pregnancies

Ook-HwanChoi, SunHeeLee, EunJinKim, KoanHoiKim, ByungYongRhim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 6 165-172 (8 pages)

Ook-HwanChoi, SunHeeLee, EunJinKim, KoanHoiKim, ByungYongRhim 저
...
- 3,000원
The aim of this study was to determine the roles of ET-1 and NO on uterine blood flow in pregnancy. Uterine arteries were isolated from 17 nonpregnant and 12 pregnant women. Nonpregnant group included patients with median age of 48.6⁑2.3 years who underwent hysterectomy, because of myoma. Pregnant group included patients with median age of 31.3⁑1.4 years undergoing cesarean delivery. ET-1 and ET-2 induced concentration-dependent contraction in isolated nonpregnant and pregnant...
694.

Peripheral Nerve Injury Alters Excitatory and Inhibitory Synaptic Transmission in Rat Spinal Cord Substantia Gelatinosa

Dong-HoYoun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 2 143-148 (6 pages)

Dong-HoYoun 저
...
- 3,000원
Following peripheral nerve injury, excessive nociceptive inputs result in diverse physiological alterations in the spinal cord substantia gelatinosa (SG), lamina II of the dorsal horn. Here, I report the alterations of excitatory or inhibitory transmission in the SG of a rat model for neuropathic pain ("spared nerve injury"). Results from whole-cell recordings of SG neurons show that the number of distinct primary afferent fibers, identified by graded intensity of stimulation, is...
695.

Inhibition of Angiotensin II-Induced Vascular Smooth Muscle Cell Hypertrophy by Different Catechins

YingZheng, HyeJinSong, SeokHeeYun, YeonJeongChae, HaoJia, ChanHyungKim, TaeSunHa, AgapiosSachinidis, HeeYulAhn, SraT.Davidge 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 7 117-124 (8 pages)

YingZheng, HyeJinSong, SeokHeeYun, YeonJeongChae, HaoJia, ChanHyungKim, TaeSunHa, AgapiosSachinidis, HeeYulAhn, SraT.Davidge 저
...
- 3,000원
A cumulative evidence indicates that consumption of tea catechin, flavan-3-ol derived from green tea leaves, lowers the risk of cardiovascular diseases. However, a precise mechanism for this cardiovascular action has not yet been fully understood. In the present study, we investigated the effects of different green tea catechins, such as epigallocatechin-3 gallate (EGCG), epigallocatechin (EGC), epicatechin-3 gallate (ECG), and epicatechin (EC), on angiotensin II (Ang II)-induced hypertrophy in...
696.

Regulation of L-type Calcium Channel Current by Somatostatin in Guinea-Pig Gastric Myocytes

YoungChulKim, JaeHoonSim, SangJinLee, TongMookKang, SungJoonKim, SeungRyulKim, SeiJinYoun, SangJeonLee, Wen-XieXu6, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 5 103-108 (6 pages)

YoungChulKim, JaeHoonSim, SangJinLee, TongMookKang, SungJoonKim, SeungRyulKim, SeiJinYoun, SangJeonLee, Wen-XieXu6, InsukSo, KiWhanKim 저
...
- 3,000원
To study the direct effect of somatostatin (SS) on calcium channel current (IBa) in guinea-pig gastric myocytes, IBa was recorded by using whole-cell patch clamp technique in single smooth muscle cells. Nicardipine (1μM), a L-type Ca2+ channel blocker, inhibited IBa by 98⁑1.9% (n=5), however IBa was decreased in a reversible manner by application of SS. The peak IBa at 0 mV were decreased to 95⁑1.1, 92⁑1.9, 82⁑4.0, 66⁑5.8, 10⁑2.9% at 10⁣10, 10⁣9,...
697.

Ca2+-induced Ca2+ Release from Sarcoplasmic Reticulum Negatively Regulates Myocytic ANP Release in Beating Rabbit Atria

DanLi, HeXiuQuan, JinFuWen, JingYuJin, SungHunPark, SunYoungKim, SungZooKim, KyungWooCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 3 87-94 (8 pages)

DanLi, HeXiuQuan, JinFuWen, JingYuJin, SungHunPark, SunYoungKim, SungZooKim, KyungWooCho 저
...
- 3,000원
It is not clear whether Ca2⁢-induced Ca2⁢ release from the sarcoplasmic reticulum (SR) is involved in the regulation of atrial natriuretic peptide (ANP) release. Previously, we have shown that nifedipine increased ANP release, indicating that Ca2⁢ entry via voltage-gated L-type Ca2⁢ channel activation decreases ANP release. The purpose of the present study was two-fold: to define the role of SR Ca2⁢ release in the regulation of ANP release and whether Ca2⁢...
698.

TASK-1 Channel Promotes Hydrogen Peroxide Induced Apoptosis

JihyunYun, SeungtaeKim, HyoweonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 9 63-67 (5 pages)

JihyunYun, SeungtaeKim, HyoweonBang 저
...
- 1,500원
Hydrogen peroxide (H2O2) causes oxidative stress and is considered as an inducer of cell death in various tissues. Two-pore domain K⁢ (K2p) channels may mediate K⁢ efflux during apoptotic volume decreases (AVD) in zygotes and in mouse embryos. In the present study, we sought to elucidate linkage between K2p channels and cell death by H2O2. Thus K2p channels (TASK-1, TASK-3, TREK-1, TREK-2) were stably transfected in HEK-293 cells, and cytotoxicity assay was preformed using cell...
699.

D-Amphetamine Causes Dual Actions on Catecholamine Release from the Rat Adrenal Medulla

Geon-HanLim, Gwang-MoonNa, Seon-YoungMin, Yoo-SeokSeo, Chan-WonPark, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 7 45-54 (10 pages)

Geon-HanLim, Gwang-MoonNa, Seon-YoungMin, Yoo-SeokSeo, Chan-WonPark, Dong-YoonLim 저
...
- 3,000원
a selective neuronal nicotinic Nn-receptor agonist) and McN-A-343 (10⁣4 M, a selective M1-muscarinic agonist) only for the first period (4 min), although it alone has weak effect on CA secretion. Moreover, d-amphetamine (30μM) in to an adrenal vein for 60 min also augmented the CA release evoked by BAY-K-8644, an activator of the dihydropyridine L-type Ca2⁢ channels, and cyclopiazonic acid, an inhibitor of cytoplasmic Ca2⁢ ATPase only for the first period (4 min). However, in...
700.

Buffering Contribution of Mitochondria to the [Ca2+]i Increase by Ca2+ Influx through Background Nonselective Cation Channels in Rabbit Aortic Endothelial Cells

YoungChulKim, SangJinLee, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 5 29-36 (8 pages)

YoungChulKim, SangJinLee, KiWhanKim 저
...
- 3,000원
To prove the buffering contribution of mitochondria to the increase of intracellular Ca2+ level ([Ca2+]i) via background nonselective cation channel (background NSCC), we examined whether inhibition of mitochondria by protonophore carbonylcyanide m-chlorophenylhydrazone (CCCP) affects endothelial Ca2+ entry and Ca2+ buffering in freshly isolated rabbit aortic endothelial cells (RAECs). The ratio of fluorescence by fura-2 AM (R340/380) was measured in RAECs. Biological state was checked by...

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