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Effects of cGMP on the Contractility and Ca Movement in the Aorta of Normotensive Wistar-Kyoto Rats and Spontaneously Hypertensive Rats
Park, Hae-Kun, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Chang, Seok-Jong 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 8 181-190 (10 pages)
Endothelium-derived relaxing factor (EDRF) activates guanylate cyclase which mediates the formation of cGMP from GTP in vascular smooth muscle. It is well known that endothelium-dependent relaxation is impaired in spontaneously hypertensive rats (SHR). However, it is still unknown whether the impaired endothelium-dependent relaxation in SHR results from the reduced release of EDRF or from the decrease of vascular response to EDRF. We investigated the effects of cGMP on the contractility and Ca... -
Effect of pH on the Vascular Tone and 45Ca Uptake in the Aorta of Spontaneously Hypertensive Rats
Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Park, Hae-Kun 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 7 169-180 (12 pages)
The effect of extracellular and intracellular pH on vascular tone and 45Ca uptake were investigated in aortic strips and dispersed single aortic smooth muscle cells of spontaneously hypertensive rats (SHR) and aged-matched Wistar-Kyoto rats (WKY). The contraction produced by a change of extracellular pH (pHo) in the range of 6.5 ~ 8.3 was estimated by comparison with the level of vascular tone at pH 7.4. Contraction was induced below pHo 6.5 in WKY, pHo 7.1 in SHR, and over pHo 8.0 on both... -
Ca-dependent Alteration in Basal Tone, Basal 45Ca Uptake and 3H-nitrendipine Binding in the Aorta of Spontaneously Hypertensive Rats
Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Hoe-Suk 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 1호 3 27-36 (10 pages)
of endothelial rubbing, compared with that of intact endothelium. Basal 45Ca uptake in the aortic single smooth muscle cells of SHR was greater than that of WKY (p<0.01), Specific bindings of [3H]nitrendipine in the aortic single smooth muscles of SHR and WKY were saturable. The dissociation constant (Kd) was 0.71±0.15 and 1.18±0.08nM SHR, respectively, and the difference in Kd between two strains was statistically significant (p<0.03). The maximal binding capacity (Bmax) was 34.6±3.2 and... -
Effects of the Endothelium on the Contractile Responses to Norepinephrine in Isolated Proximal and Distal Coronary Artery of Pigs
Kim, Jong-Hoon, Jeon, Byeong-Hwa, Chang, Seok-Jong, Park, Hae-Kun 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 3 27-36 (10 pages)
rubbing of endothelium in both arteries. α1-and α2-adrenoceptor mediated contraction by NE were potentiated by rubbing of endothelium in both arteries. Pretreatment with methylene blue, an inhibitor of soluble guanylate cyclase, increased α1- and α2-adrenoceptor mediated contraction by NE in both arteries with endothelium. From the above results, we suggest that the effect of activation of α-adrenoceptors by NE may be modulated by endothelium in the proximal and distal coronary arteries... -
Effects of Intermittent Sciatic Nerve Stimulation on the Soleus and Medial Gastrocnemius Muscle Atrophy in Hindlimb Suspended Rats
Park, Byung-Rim, Cho, Jung-Shick, Kim, Min-Sun, Chun, Sang-Woo 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 2호 8 159-166 (8 pages)
The present study was designed to evaluate effects of intermittent electrical stimulation of the sciatic nerve on the atrophic response of antigravity muscles, such as the soleus (slow m.) and medial gastrocnemius (fast m.) muscles. Rats (Sprague-Dawley, 245-255g) were subjected to a hindlimb suspension and divided into three groups : one was with hindlimb suspension (MS) and another with hindlimb suspension plus intermittent electrical stimulation of the sciatic nerve (HS ES). Control group... -
토끼 대동맥 평활근의 내피세포 의존성 이완에 미치는 Ca2+ 및 Ca2+ 길항제의 효과
서석효(Suh, Suk-Hyo), 구용숙(Goo, Yong-Sook), 박춘옥(Park, Choon-Ok), 황상익(Hwang, Sang-Ik), 김기환(Kim, Ki-Whan) 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1990, 제 24권 제 1호 8 91-102 (12 pages)
토끼 흉부 대동맥을 이용하여 내피세포 의존성 혈관이완에 대한 세포외 Ca2+과 여러가지 Ca2+ 길항제의 효과를 분석하여 EDRF의 작용기전을 밝혀 보고자 하였다. 대동맥 횡단 절편의 등장성 수축은 10-7 M 노에피네프린으로 유발시켰으며, 10-6 M 사세틸콜린으로 내피세포 의존성 혈관이완을 일으켰다. 내피세포는 작은 솜뭉치로 부드럽게 문질러서 제거하였으며, hemolysate를 사용하여 EDRF에 대한 헤모글로빈의 효과를 관찰하였다. 결과를 종합하면 다음과 같다. 1) 아세틸콜린에 의한 내피세포 의존성 혈관이완은 두 시기, 즉... -
한국인(韓國人) 서어비스업(業) 종사자(從事者)의 대사량(代謝量)에 관(關)한 연구(硏究)
김애주(Kim, Ae-Ju) 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1970, 제 4권 제 2호 10 69-82 (14 pages)
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Synergistic Interactions of Schizostatin Identified from Schizophyllum commune with Demethylation Inhibitor Fungicides
Min Young Park, Byeong Jun Jeon, Ji Eun Kang, Beom Seok Kim 한국식물병리학회 The Plant Pathology Journal 12 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 6호 5 579-590 (12 pages)
Botrytis cinerea, which causes gray mold disease in more than 200 plant species, is an economically important pathogen that is mainly controlled by synthetic fungicides. Synergistic fungicide mixtures can help reduce fungicide residues in the environment and mitigate the development of fungicide-resistant strains. In this study, we screened microbial culture extracts on Botrytis cinerea to identify an antifungal synergist for tebuconazole. Among the 4,006 microbial extracts screened in this... -
Visualization of Phytophthora palmivora Infection in Oil Palm Leaflets with Fluorescent Proteins and Cell Viability Markers
Juan C. Ochoa, Mariana Herrera, M?nica Navia, Hern?n Mauricio Romero 한국식물병리학회 The Plant Pathology Journal 13 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 1호 3 19-31 (13 pages)
Bud rot (BR) is the most devastating disease affecting oil palm (Elaeis guineensis) crops in Colombia. Its causal agent, Phytophthora palmivora, initiates the infection in immature oil palm leaflets producing necrotic lesions, followed by colonization of opportunistic necrotrophs, which increases disease damage. To improve the characterization of the disease, we transformed P. palmivora using Agrobacterium tumefaciens-mediated transformation (ATMT) to include the fluorescent proteins CFPSKL... -
A Model to Explain Temperature Dependent Systemic Infection of Potato Plants by Potato virus Y
한국식물병리학회 The Plant Pathology Journal 6 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 2호 12 206-211 (6 pages)
The effect of temperature on the rate of systemic infection of potatoes (Solanum tuberosum L. cv. Chu-Baek) by Potato virus Y (PVY) was studied in growth chambers. Systemic infection of PVY was observed only within the temperature range of 16°C to 32°C. Within this temperature range, the time required for a plant to become infected systemically decreased from 14 days at 20°C to 5.7 days at 28°C. The estimated lower thermal threshold was 15.6°C and the...


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