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881.

The Protective Role of TLR3 and TLR9 Ligands in Human Pharyngeal Epithelial Cells Infected with Influenza A Virus

YanHan, Zhi-jianBo, Ming-yuXu, NanSun, Dan-hongLiu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 5 225-231 (7 pages)

YanHan, Zhi-jianBo, Ming-yuXu, NanSun, Dan-hongLiu 저
...
- 3,000원
In this study we aim to extensively investigate the anti-influenza virus immune responses in human pharyngeal epithelial cell line (Hep-2) and evaluate the protective role of Toll-like receptor (TLR) ligands in seasonal influenza A H1N1 (sH1N1) infections in vitro. We first investigated the expression of the TLRs and cytokines genes in resting and sH1N1 infected Hep-2 cells. Clear expressions of TLR3, TLR9, interleukin (IL)-6, tumour necrosis factor (TNF)-α and interferon (IFN)-β were detected...
882.

Naloxone Postconditioning Alleviates Rat Myocardial Ischemia Reperfusion Injury by Inhibiting JNK Activity

AnzhouXia, ZhiXue, WeiWang, TanZhang, TiantianWei, XingzhiSha, YixunDing, WeidongZhou 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.1 9 67-72 (6 pages)

AnzhouXia, ZhiXue, WeiWang, TanZhang, TiantianWei, XingzhiSha, YixunDing, WeidongZhou 저
...
- 3,000원
To investigate the alteration of c-Jun N-terminal kinase (JNK) activity after myocardial ischemia reperfusion injury (MIRI) and further explore the effect of naloxone postconditioning on MIRI. Forty male Sprague Dawley rats were randomly divided into five groups: sham operation (sham, n=8); ischemia reperfusion (IR, n=8); IR+naloxone 0.5 mg/kg (Nal L, n=8); IR+naloxone 1.0 mg/kg (Nal M, n=8); IR+naloxone 2.0 mg/kg (Nal H, n=8). Pathological changes of myocardial tissue were visualized by HE...
883.

Activation of G Proteins by Aluminum Fluoride Enhances RANKL- Mediated Osteoclastogenesis

BoryungPark, Yu-MiYang, Byung-JaiChoi, MinSeukKim, DongMinShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 8 427-433 (7 pages)

BoryungPark, Yu-MiYang, Byung-JaiChoi, MinSeukKim, DongMinShin 저
...
- 3,000원
Receptor activator of NF-ՊB ligand (RANKL)-induced osteoclastogenesis is accompanied by intra-cellular Ca2＋ mobilization in a form of oscillations, which plays essential roles by activating sequen-tially Ca2＋/calmodulin-dependent protein kinase, calcineurin and NFATc1, necessary in the osteoclast differentiation. However, it is not known whether Ca2＋ mobilization which is evoked in RANKL-in-dependent way induces to differentiate into osteoclasts. In present study, we investigated Ca2＋...
884.

TRPM7 Is Essential for RANKL-Induced Osteoclastogenesis

Yu-MiYang, Hwi-HoonJung, SungJunLee, Hyung-JunChoi, MinSeukKim, DongMinShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 10 65-71 (7 pages)

Yu-MiYang, Hwi-HoonJung, SungJunLee, Hyung-JunChoi, MinSeukKim, DongMinShin 저
...
- 3,000원
The transient receptor potential melastatin type 7 (TRPM7) channel is a widely expressed non- selective cation channel with fusion to the C-terminal alpha kinase domain and regarded as a key regulator of whole body Mg2+ homeostasis in mammals. However, the roles of TRPM7 during osteoclastogenesis in RAW264.7 cells and bone marrow-derived monocyte/macrophage precursor cells (BMMs) are not clear. In the present study, we investigate the roles of TRPM7 in osteoclastogenesis using methods of small...
885.

CD40 Co-stimulation Inhibits Sustained BCR-induced Ca2＋ Signaling in Response to Long-term Antigenic Stimulation of Immature B Cells

YenHoangNguyen, Ki-YoungLee, TaeJinKim, SungJoonKim, TongMookKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 9 179-187 (9 pages)

YenHoangNguyen, Ki-YoungLee, TaeJinKim, SungJoonKim, TongMookKang 저
...
- 3,000원
Regulation of B cell receptor (BCR)-induced Ca2＋ signaling by CD40 co-stimulation was compared in long-term BCR-stimulated immature (WEHI-231) and mature (Bal-17) B cells. In response to long-term pre-stimulation of immature WEHI-231 cells to Ձ-IgM antibody (0.5∼48 hr), the initial transient decrease in BCR-induced [Ca2＋]i was followed by spontaneous recovery to control level within 24 hr. The recovery of Ca2＋ signaling in WEHI-231 cells was not due to restoration of internalized...
886.

PKC-Independent Stimulation of Cardiac Na+/Ca2+ Exchanger by Staurosporine

TongMookKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.5 7 259-266 (8 pages)

TongMookKang 저
...
- 3,000원
[Ca2+]i transients by reverse mode of cardiac Na+/Ca2+ exchanger (NCX1) were recorded in fura-2 loaded BHK cells with stable expression of NCX1. Repeated stimulation of reverse NCX1 produced a long-lasting decrease of Ca2+ transients ('rundown'). Rundown of NCX1 was independent of membrane PIP2 depletion. Although the activation of protein kinase C (PKC) was observed during the Ca2+ transients, neither a selective PKC inhibitor (calphostin C) nor a PKC activator (PMA) changed the degrees of...
887.

Comparison of Interleukin-8 Levels in Long-Distance Runners and Healthy Sedentary Non-Athletic Control Subjects

Young-OhShin, Jun-SangBae, Ji-WonMin, Jeong-BeomLee, Jung-KyuKim, Young-JuSong, Hun-MoYang, Young-KiMin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.6 6 263-268 (6 pages)

Young-OhShin, Jun-SangBae, Ji-WonMin, Jeong-BeomLee, Jung-KyuKim, Young-JuSong, Hun-MoYang, Young-KiMin 저
...
- 3,000원
We have previously demonstrated that the level of leukocytes and neutrophils significantly increased immediately and 30 min after exercise. Interleukin-8 (IL-8) is an inflammatory cytokine that acts as a chemokine on neutrophils. In the present study, we evaluated the correlation between the number of neutrophils and leukocytes, and between the number of neutrophils and plasma IL-8 level. Long-distance trained runners (TRs, n = 10) and untrained sedentary control subjects (SEDs, n = 10) ran for...
888.

CD40 Activation Protects Dendritic Cells from Anticancer Drug-Induced Apoptosis

Jae-YeonJunHong-GuJoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.5 2 255-259 (5 pages)

Jae-YeonJunHong-GuJoo 저
...
- 1,500원
Dendritic cells (DCs) play a critical role in various immune responses involving CD4⁢ T cells and have been used to generate anti-tumor immunity. Chemotherapy induces severe side effects including immunosuppression in patients with cancer. Although immunosuppression has been studied, the effects of anticancer drugs on DCs are not fully determined. In this study, we demonstrated that CD40 activation strongly protected DCs from 5-fluorouracil (5-FU) or mitomycin C-induced apoptosis. DC-...
889.

Altered Expression of Aquaporins in Rat Submandibular Glands after Parasympathetic Denervation

JiYeonJung, KangOkByun, WonJaeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 8 97-101 (5 pages)

JiYeonJung, KangOkByun, WonJaeKim 저
...
- 1,500원
The salivary glands produce 1.5L of fluid per day. As in other exocrine organs, the general mechanism in the salivary glands is that water movement occurs secondary to osmotic driving forces created by active salt transport. Therefore, high water permeability in the salivary glands is expected to have a variety of aquaporin (AQP), a water channel. Although some AQPs have been known to be present in the salivary glands, roles of parasympathetic nerve in AQP expression have not yet been examined....
890.

Modulation of Pituitary Somatostatin Receptor Subtype (sst1-5) mRNA Levels by Growth Hormone (GH)-Releasing Hormone in Purified Somatotropes

SeungjoonPark, HeesoonPark, MinaLee, SookjinSohn, EunheeKim, JeechangJung, LawrenceA.Frohman, RhondaD.Kineman 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 5 79-84 (6 pages)

SeungjoonPark, HeesoonPark, MinaLee, SookjinSohn, EunheeKim, JeechangJung, LawrenceA.Frohman, RhondaD.Kineman 저
...
- 3,000원
We have previously reported that expression of the somatostatin receptor subtypes, sst1-5, is differentially regulated by growth hormone (GH)-releasing hormone (GHRH) and forskolin (FSK), in vitro. GHRH binds to membrane receptors selectively located on pituitary somatotropes, activates adenylyl cyclase (AC) and increases sst1 and sst2 and decreases sst5 mRNA levels, without significantly altering the expression of sst3 and sst4. In contrast FSK directly activates AC in all pituitary cell types...

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