간행물
- 대한수의학회 학술대회발표집(11)
- JOURNAL OF VETERINARY SCIENCE(8)
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(4)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(3)
- ARCHIVES OF PHARMACAL RESEARCH : A PUBLICATION OF THE PHARMACEUTICAL SOCIETY OF KOREA(2)
- 대한한방비만학회지(2)
- 대한생리학회지(1)
- 대한약리학잡지(1)
- 한국환경위생학회지(1)
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Study on Anti-estrogenic Activity of DEHP as an Endocrine Disruption Chemical
Kim. Eun-Joo 한국환경보건학회 한국환경위생학회지 9 Pages
한국환경보건학회 한국환경위생학회지 2003, Vol.29 No.2 7-15 (9 pages)
DEHP는 대표적인 플라스틱 가소제 가운데 하나로서, 광범위하게 사용되고 있으며, 내분비계 장애물질로 분류퇴고 있다. 실제로 하천, 해양, 토양 등 광범위한 환경에서 검출되고 있지만, 이 물질이 수서 생물에 미치는 내분비교란 영향과 기작에 대해서는 거의 알려진 바가 없다. 본 연구에서는 송사리로 불리우는 Oryzias latipes(Japanese medaka)와, 유생 시기에 저니성 무척추 동물로 존재하다가 성충이 되는 Chironomus riparius를 대상으로 DEHP가 내분비 장애물질로서 생식작용에 미치는 영향에 대하여 연구하였다. 먼저, Japanese... -
Anti-Estrogenic Activity of Lignans from Acanthopanax chiisanensis Root
Lee. Sanghyun, Yoo. Hye Hyun, Piao. Xiang Lan, Kim. Ju Sun, Kang. Sam Sik, Shin. Kuk Hyun 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 4 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2005, Vol.28 No.2 186-189 (4 pages)
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Requirement of Metabolic Activation for Estrogenic Activity of Pueraria mirifica
Y.S. Lee, J.S. Park, S.D. Cho, J.K. Son, W. Cherdshewasart and K.S. Kang 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 4호 4 273-277 (5 pages)
beta-estradiol (positive control) showed high estrogenic activity. Estrogenic activities were induced at 2.5 ng/ml to 25 microg/ml concentrations of PM in a dose-dependent manner on MCF-7 cells and the estrogenic effect of PM was blocked by tamoxifen treatment, a well-known anti-estrogen. PM also showed estrogenic effect on human hepatoma cell line, HepG2 cells, containing estrogen receptor and luciferase reporter gene. Taken together, PM in itself may have no estrogenicity in yeast system, but... -
2-(4-Hydroxyphenyl)-5-(3-Hydroxypropenyl)-7-Methoxybenzofuran, a Novel Ailanthoidol Derivative, Exerts Anti-Inflammatory Effect through Downregulation of Mitogen-Activated Protein Kinase in Lipopolysaccharide-Treated RAW 264.7 Cells
HyeonJinKim, Jong-GabJun, Jin-KyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.3 6 217-222 (6 pages)
a neolignan from Zanthoxylum ailanthoides and Salvia miltiorrhiza Bunge, inhibited inflammatory reactions by macrophages and protected mice from endotoxin shock. We examined the anti-inflammatory activity of six synthetic ailanthoidol derivatives (compounds 1-6). Among them, compound 4, 2-(4-hydroxyphenyl)-5-(3-hydroxypropenyl)-7-methoxybenzofuran, had the lowest IC50 value concerning nitric oxide (NO) release from lipopolysaccharide (LPS)-stimulated RAW264.7 cells. Compound 4 suppressed the... -
Identification of Estrogenic and Antiestrogenic Activities of Respirable Diesel Exhaust Particles by Bioassay-directed Fractionation
Oh. Seung-Min, Ryu. Byung-Taek, Chung. Kyu-Hyuck 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 8 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2008, Vol.31 No.1 75-82 (8 pages)
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Evaluation of the estrogenic effects of dietary perinatal Trifolium pratense
Emrah Yatkin, Suzan Daglioglu 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 2호 3 121-126 (6 pages)
This study was designed to investigate the potential estrogenic effects of perinatal dietary phytoestrogens on the rat uterus. Pregnant rats were divided to three groups provided the following diets: (1) rat chow, (2) rat chow with 7.5% Trifolium (T.) pratense, or (3) rat chow supplemented with 17β-estradiol (0.5 mg/kg). The dams in each group were kept on the same diet during pregnancy and lactation. Female offspring were euthanized on day 21 at which time body and organ weights were recorded... -
PDGF-C and PDGF α-Receptor in Mouse during Embryogenesis
In Shik Kim, Dong Choon Ahn, Byung Yong Park 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 319 508-509 (2 pages)
