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전체 선택해제
총 31건 검색
본문검색 결과만 보기
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CD40 Co-stimulation Inhibits Sustained BCR-induced Ca2＋ Signaling in Response to Long-term Antigenic Stimulation of Immature B Cells
YenHoangNguyen, Ki-YoungLee, TaeJinKim, SungJoonKim, TongMookKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 9 179-187 (9 pages)
antioxidant N-acetyl-L-cysteine (NAC) strongly inhibited CD40-mediated prevention of the recovery of Ca2＋ signaling. In contrast to immature WEHI-231 cells, identical long-term Ձ-IgM pre-stimulation of mature Bal-17 cells abolished the increase in BCR-induced [Ca2＋]i, regardless of CD40 co-stimulation. These results suggest that CD40-mediated signaling prevents antigen-induced cell cycle arrest and apoptosis of immature B cells through inhibition of sustained BCR-induced Ca2＋ signaling. -
CD40 Activation Protects Dendritic Cells from Anticancer Drug-Induced Apoptosis
Jae-YeonJunHong-GuJoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.5 2 255-259 (5 pages)
immunity. Chemotherapy induces severe side effects including immunosuppression in patients with cancer. Although immunosuppression has been studied, the effects of anticancer drugs on DCs are not fully determined. In this study, we demonstrated that CD40 activation strongly protected DCs from 5-fluorouracil (5-FU) or mitomycin C-induced apoptosis. DC- specific surface markers, including CD11c and major histocompatibility complex (MHC) class II, were used for identifying DCs. CD 40 activation wit... -
Up-Regulation of Interleukin-4 Receptor Expression by Interleukin-4 and CD40 Ligation via Tyrosine Kinase-Dependent Pathway
Kim. Hyun-Il, So. Eui-Young, Yoon. Suk-Ran, Han. Mi-Young, Lee. Choong-Eun 생화학분자생물학회 Journal of biochemistry and molecular biology 6 Pages
생화학분자생물학회 Journal of biochemistry and molecular biology 1998, Vol.31 No.1 83-88 (6 pages)
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Intracellular Signaling Pathways for Type II IgE Receptor (CD23) Induction by Interleukin - 4 and Anti - CD40 Antibody
Kim. Hyun-Il, Park. Hee-Jeoung, Lee. Choong-Eun 생화학분자생물학회 Journal of biochemistry and molecular biology 7 Pages
생화학분자생물학회 Journal of biochemistry and molecular biology 1997, Vol.30 No.6 431-437 (7 pages)
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Ligation of CD40 receptor in human B lymphocytes triggers the 5-lipoxygenase pathway to produce reactive oxygen species and activate p38 MAPK
Ha. Yun-Jung, Seul. Hee-Jung, Lee. Jong-Ran 생화학분자생물학회 Experimental & molecular medicine : EMM 10 Pages
생화학분자생물학회 Experimental & molecular medicine : EMM 2011, Vol.43 No.2 101-110 (10 pages)
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원발성 폐선암환자의 말초혈액에서 분리한 CD1c+ 골수성 수지상 세포에서의 CD40, CD86 및 HLA-DR의 발현
강문철, 강창현, 김영태, 김주현, Kang. Moon-Chul, Kang. Chang-Hyun, Kim. Young-Tae, Kim. Joo-Hyun 대한흉부외과학회 大韓胸部外科學會誌 7 Pages
대한흉부외과학회 大韓胸部外科學會誌 2010, Vol.43 No.5 499-505 (7 pages)
수 있었다. PACL군과 PSqCL군 간에는 CD40의 발현이 p-value=0.319, CD86의 발현이 p-value= 0.036과 HLA-DR의 발현이 p-value=0.085로 PACL군에서 공동표지자의 발현이 감소한 양상이나 통계적 유의성은 CD86의 발현 외에는 없었다. PSqCL군과 BLD군간에는 공동표지자의 발현에 통계적 차이는 없었다. PACL군과 비선암군간에는 CD40의 발현이 p-value=0.005, CD86의 발현이 p-value=0.013과 HLA-DR의 발현이 p-value=0.004로 PACL군에서 공동표지자의 발현이 감소한 것을 통계학적으로 확인할 수 있었다. 결론: CD1c+ 골수성 수지상... -
Platelets Induce Proliferation of Human Umbilical Vein Endothelial Cells via CD154-CD40 Pathway Independently of VEGF
Cho. Wha-Jung, Ko. Eun-Mi, Cheon. In-Su, Jeoung. Doo-Il, Kim. Young-Myeong, Choe. Jong-Seon 대한면역학회 Immune network : official journal of the Korean association of immunobiologists 7 Pages
대한면역학회 Immune network : official journal of the Korean association of immunobiologists 2008, Vol.8 No.3 75-81 (7 pages)
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Role for CD40 and CD40L Expression in Generating CD8 T Cell Response to Minor Histcompatibility Antigen, H60
Jung. Kyoung-Min, Choi. Eun-Young 대한면역학회 Immune network : official journal of the Korean association of immunobiologists 6 Pages
대한면역학회 Immune network : official journal of the Korean association of immunobiologists 2007, Vol.7 No.4 173-178 (6 pages)
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Association between CD40 promoter polymorphism (rs1800686, -508 C/T) and ischemic stroke with hypertension in a Korean population
Cho. Jin-Man, Choe. Bong-Keun, Zheng. Renhua, Chon. Jinmann, Yoo. Seung Don, Kim. Chong-Jin, Gwak. Geum-Hee, Yim. Sung-Vin 대한독성유전단백체학회 Molecular & cellular toxicology 6 Pages
대한독성유전단백체학회 Molecular & cellular toxicology 2012, Vol.8 No.3 257-262 (6 pages)
