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전체 선택해제
총 68건 검색
본문검색 결과만 보기
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Multiple Effects of a Novel Epothilone Analog on Cellular Processes and Signaling Pathways Regulated by Rac1 GTPase in the Human Breast Cancer Cells
HongZhang, FanAn, LiTang, RongguoQiu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 4 109-120 (12 pages)
such as wound-closure, migration and invasion, as well as adhesion. Our study further demonstrated that UTD2 suppressed Rac1 GTPase activation and reduced the activity of PAK1, which is a downstream effector of Rac1, while the activity of Cdc42 was not affected. Additionally, the phosphorylation of p38 and ERK were significantly inhibited, but the phosphorylation of JNK remained the same after UTD2 treatment. Moreover, UTD2 inhibited the activity and mRNA expression of MMP-2, which plays a key... -
The Small GTPase CsRAC1 Is Important for Fungal Development and Pepper Anthracnose in Colletotrichum scovillei
Noh-Hyun Lee, Teng Fu, Jong-Hwan Shin, Yong-Won Song, Dong-Cheol Jang, Kyoung Su Kim 한국식물병리학회 The Plant Pathology Journal 12 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 6호 10 607-618 (12 pages)
The pepper anthracnose fungus, Colletotrichum scovil- lei, causes severe losses of pepper fruit production in the tropical and temperate zones. RAC1 is a highly conserved small GTP-binding protein in the Rho GT- Pase family. This protein has been demonstrated to play a role in fungal development, and pathogenicity in several plant pathogenic fungi. However, the functional roles of RAC1 are not characterized in C. scovillei caus- ing anthracnose on pepper fruits. Here, we generated a deletion... -
A Small GTPase RHO2 Plays an Important Role in Pre-infection Development in the Rice Blast Pathogen Magnaporthe oryzae
Teng Fu, Joon-Oh Kim, Joon-Hee Han, Adiyantara Gumilang, Yong-Hwan Lee, Kyoung Su Kim 한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2018, 34권 6호 2 470-479 (10 pages)
is a global threat to rice production. Here we characterized RHO2 gene (MGG_02457) that belongs to the Rho GTPase family, using a deletion mutant. This mutant ΔMorho2 exhibited no defects in conidiation and germination but developed only 6% of appressoria in response to a hydrophobic surface when compared to the wild-type progenitor. This result indicates that MoRHO2 plays a role in appressorium development. Furthermore, exogenous cAMP treatment on the mutant led to appressoria that exhibited... -
Nucleolar GTPase NOG-1 Regulates Development, Fat Storage, and Longevity through Insulin/IGF Signaling in C. elegans
Kim. Young-Il, Bandyopadhyay. Jaya, Cho. Injeong, Lee. Juyeon, Park. Dae Ho, Cho. Jeong Hoon 한국분자세포생물학회 Molecules and cells 7 Pages
한국분자세포생물학회 Molecules and cells 2014, Vol.37 No.1 51-57 (7 pages)
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Rac GTPase의 조절 및 세포내 기능
강광일, 강호성 한국동물학회 한국동물학회 뉴스레터 8 Pages
한국동물학회 한국동물학회 뉴스레터 1998, Vol.15 No.1 12-19 (8 pages)
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Vascular Endothelial Cadherin-mediated Cell-cell Adhesion Regulated by a Small GTPase, Rap1
Fukuhra. Shigetomo, Sakurai. Atsuko, Yamagishi. Akiko, Sako. Keisuke, Mochizuki. Naoki 생화학분자생물학회 Journal of biochemistry and molecular biology 8 Pages
생화학분자생물학회 Journal of biochemistry and molecular biology 2006, Vol.39 No.2 132-139 (8 pages)
